Mike Gillislee, NE- Gillislee has been inactive for the past few weeks with Rex Burkhead taking his spot however Burkhead suffered an injury in Week 15 that is expected to keep him out of the lineup for the next few weeks. Gillislee does not offer the pass catching abiltiy that Burkhead possess but he should take over as the short yardage and goal line carries which is a role he had earlier this season when Burkhead was on the shelf.
Peyton Barber, TB- Doug Martin was scratched in Week 15 due to a team rules violation and though he could very well be active in Week 16 against the Saints we have seen Barber average 71 rushing yards per game over the last three weeks while chipping in with a handful of receptions as well. Though the Saints defense has been much improved this season Barber still holds value.
Elijhaa Penny, ARI- The Cardinals placed Adrian Peterson on IR which lead to Kerwynn Williams as the lead back but he suffered an injury in Week 15 which has him questionable for the team's Week 16 matchup against the Giants. After the Williams injury the Cardinals turned to Penny and he totaled 45 yards on 10 carries. If he starts this week he will have a very favorable matchup and could be a decent flex play for those in need of a running back this week.
Martavis Bryant, PIT- Antonio Brown suffered an injury that will cost him the rest of the regular season and with that injury Bryant along with JuJu Smith-Schuster and Eli Rogers will all see increased value given the additional targets in the Steelers passing attack. Against New England Bryant caught four passes for 59 yards and a touchdown. He will look to carry that big play ability into Week 16 against a bad Texans defense.
Antonio Gates, LAC- The 37-year old Gates is expected to see a large role in the Chargers offense in Week 16 after starting tight end Hunter Henry was placed on IR due to an injury suffered in Week 15. Gates caught a touchdown pass in Week 15 to add to his already Hall of Fame resume. Philip Rivers does like targeting his tight ends and though he is certainly a big risk we could very well see Gates look to end his career on a high note over the final two weeks of the regular season.