Fantasy Football Week 6 WR/CB Matchups 2026: WR vs. CB Matchup Report

Every Week 6 wide receiver matchup, built the way a real game plan works: each team's outside receivers against the specific cornerback who will be lined up across from them, plus the slot receiver against the nickel corner, not just a generic name-vs-name ranking. This report folds together current PFF coverage grades, season-to-date stat lines, this week's Vegas lines, and the latest verified injury and depth-chart news to sort every notable wide receiver into Safe, Moderate, and Risky tiers. Cincinnati, Detroit, Miami, and Minnesota are on bye, so you will find all 14 games on the Week 6 slate broken down three ways: left WR vs. right CB, right WR vs. left CB, and slot vs. nickel corner. Below you'll find the best matchups to target, the toughest draws to work around, and the full breakdown for every game.

Best Fantasy Football WR Matchups for Week 6

Toughest Fantasy Football WR Matchups for Week 6

Fantasy Football Week 6 WR/CB Matchup Report

Left Wide Receiver (LWR) vs. Right Cornerback (RCB)

Each team's outside receiver on the left side of the formation against the opponent's right cornerback.

Drake London (ATL)

vs. Malik Muhammad II (CHI)   •   Matchup: Safe

London is the engine of Atlanta's offense: 27 catches on 37 targets for 488 yards through five games, including 7 catches for 118 yards on 11 targets in the overtime loss to Baltimore. The only worry is the quarterback, since Michael Penix left that game with a rib injury, though he's practicing and Kevin Stefanski said he'll likely start. Muhammad's 48.5 coverage grade is one of the weaker marks at the position. Atlanta is a 2.5-point home underdog with a 50.5 total, a script that should keep the targets flowing. Start him with confidence, and the first touchdown has to be coming.

Rashod Bateman (BAL)

vs. Tyson Campbell (CLE)   •   Matchup: Moderate

Bateman is a steady WR3 in Baltimore's offense, with 16 catches on 21 targets for 233 yards and a touchdown, and he went for 5 catches and 62 yards on 6 targets in the overtime win over Atlanta. Lamar Jackson (ankle) has a realistic chance to return after Tyler Huntley held the offense together, and a healthy Jackson helps every Ravens receiver. Campbell's 64.6 coverage grade is a fair, middle-of-the-road test. Baltimore is a 5.5-point road favorite with a 42.5 total, which carries some risk of a run-heavy script. He's a solid flex with modest upside.

Keon Coleman (BUF)

vs. Hezekiah Masses (LV)   •   Matchup: Moderate

Coleman has produced in three straight games with DJ Moore sidelined or limited, and he sits at 15 catches on 18 targets for 224 yards and 2 touchdowns. Last week was quiet on paper: 1 official catch for 7 yards, but that one was a touchdown. Masses carries a 46.2 coverage grade, a very beatable matchup. Buffalo is a 5.5-point road favorite in a game with a 53.5 total, tied for the highest on the slate, though a lead could mean fewer throws late. He's a good flex, and his target share grows if Moore (shoulder) is out again.

Tetairoa McMillan (CAR)

vs. Quinyon Mitchell (PHI)   •   Matchup: Moderate

McMillan is a true No. 1 receiver, with 26 catches on 39 targets for 385 yards and 2 touchdowns in four games, and he had a career day against Detroit with 14 catches for 192 yards and 2 scores on 16 targets. Carolina is fresh off its bye, and Jalen Coker's return will pull a few looks away. Mitchell's 73.9 coverage grade is below his reputation as one of the league's best young corners, but he's still a real test. Carolina is a 1.5-point road favorite with a 40.5 total, a low number that tempers everything. He's a high-end WR2 who is hard to bench.

Rome Odunze (CHI)

vs. C.J. Henderson (ATL)   •   Matchup: Risky

Odunze has been a letdown: 17 catches on 29 targets for 273 yards and no touchdowns, and he caught just 3 of 9 targets for 40 yards in the blowout loss to Green Bay. Caleb Williams is pushing to return from his hamstring strain and practiced in full, but Chicago hasn't confirmed its starter. Henderson's 73.4 coverage grade makes this a tough draw. Chicago is a 2.5-point road favorite with a 50.5 total. He's a boom-or-bust flex until the efficiency shows up.

Denzel Boston (CLE)

vs. Nate Wiggins (BAL)   •   Matchup: Moderate

Boston is Cleveland's top receiver, with 16 catches on 29 targets for 330 yards and 3 touchdowns, and he caught a score on 3 catches for 46 yards in the loss to the Jets. With KC Concepcion in the concussion protocol, he should absorb even more targets alongside Jerry Jeudy and Isaiah Bond. Wiggins' 67.7 coverage grade is a legitimate test. Cleveland is a 5.5-point home underdog with a 42.5 total, which points to pass volume. He's a strong WR3 with WR2 upside.

George Pickens (DAL)

vs. Brandon Cisse (GB)   •   Matchup: Safe

Pickens carried Dallas last week, catching 9 of 13 targets for 130 yards and a touchdown after CeeDee Lamb left with a quad bruise, and he's at 27 catches for 355 yards on the season. Even if Lamb plays, Pickens has shown he can be the engine of the passing game. Cisse's 59.8 coverage grade is middling, and Green Bay's secondary has been hit by illness. Dallas is a 1.5-point road underdog on Sunday night with a 53.5 total, a perfect shootout script. Start him as a WR1.

Courtland Sutton (DEN)

vs. Josh Jobe (SEA)   •   Matchup: Risky

Sutton has been dreadful for a player with this much opportunity: 11 catches on 25 targets for 104 yards, with 2 catches for 18 yards and a touchdown last week against the Chargers. With Pat Bryant now on injured reserve, targets should flow toward Jaylen Waddle first. Jobe's 50.8 coverage grade is a soft matchup, but the production simply isn't there. Denver is a 2.5-point home underdog on Thursday night with a 40.5 total, a low-scoring spot. He's a touchdown-or-bust flex.

Christian Watson (GB)

vs. Joey Porter (DAL)   •   Matchup: Safe

Watson is a top-three receiver this week for good reason: 26 catches on 40 targets for 474 yards and 6 touchdowns, including 6 catches for 143 yards and 2 scores in the rout of Chicago. Jordan Love has been sharp, and Watson and Matthew Golden have been his favorite targets. Dallas has a banged-up secondary, with both DaRon Bland and Joey Porter dealing with illness. Green Bay is a 1.5-point home favorite on Sunday night with a 53.5 total. Lock him in.

Nico Collins (HOU)

vs. Montaric Brown (JAX)   •   Matchup: Safe

Collins is healthy again and a top-five receiver this week, with 19 catches for 249 yards and 3 touchdowns in the three games he's played, including 5 for 56 on 7 targets in the win over Tennessee. Marvin Harrison joins the offense, but Collins remains the clear alpha for C.J. Stroud. Brown's 45.8 coverage grade is one of the weakest at the position. Houston is a 2.5-point road underdog in London with a 42.5 total, which favors passing. Start him without a second thought.

Laquon Treadwell (IND)

vs. Alontae Taylor (TEN)   •   Matchup: Risky

Treadwell has been on the field plenty with Alec Pierce on injured reserve, but the production has been thin: 11 catches on 19 targets for 157 yards, and just 2 for 34 on 8 targets against Pittsburgh. Keenan Allen and Josh Downs get the first looks, and Darius Slayton (knee) is also questionable. Taylor's 29.8 coverage grade is one of the lowest in the league, which is the only reason he's on the radar. Indianapolis is a 7-point home favorite with a 44.5 total. He's a deep-league dart only.

Brian Thomas (JAX)

vs. Kamari Lassiter (HOU)   •   Matchup: Risky

Thomas has been a non-factor in a Jacksonville offense that runs through Parker Washington, with 9 catches on 18 targets for 105 yards and a touchdown, and he didn't catch any of his 3 targets in the win over Philadelphia. Lassiter's 59.6 coverage grade is average, but Houston's pass defense is better than that number suggests. Jacksonville is a 2.5-point home favorite in London with a 42.5 total, and the first-place Jaguars (4-1) will lean on what's working. He's a bench candidate until the targets come back.

Marquez Valdes-Scantling (LAC)

vs. Mansoor Delane (KC)   •   Matchup: Risky

With Quentin Johnston (chest) ruled out, and Tre' Harris (hamstring) week-to-week, Marquez Valdes-Scantling is in line for a big snap share in a decimated Chargers receiver room. He has just 2 catches on 5 targets for 22 yards this season, so the production isn't there. Mansoor Delane's 85.0 coverage grade is among the best in the league. Los Angeles is an 8.5-point road underdog with a 42.5 total, which means throwing, but Ladd McConkey (foot) is also in doubt. He's a deep-league dart in a bad offense.

Davante Adams (LAR)

vs. Denzel Burke (ARI)   •   Matchup: Moderate

Adams has been a touchdown machine, with 27 catches on 45 targets for 441 yards and 4 touchdowns, including 5 catches for 51 yards and 2 scores last week, while Puka Nacua soaked up 24 targets. Burke's 55.0 coverage grade is a soft draw. The concern is the script: the Rams are 12.5-point home favorites with a 51.5 total, and a big lead means more handoffs late. Adams is a good WR2 with a real touchdown floor.

Romeo Doubs (NE)

vs. Brandon Stephens (NYJ)   •   Matchup: Risky

Doubs was the least productive Patriots wideout last week, catching 1 of 3 official targets for 16 yards despite playing 83% of the snaps, and he's at 13 catches on 23 targets for 219 yards and 2 touchdowns. A.J. Brown's practice window opened Wednesday, and he's trying to play Sunday, though Ian Rapoport says it may be a bit early, and a Brown return would cut into Doubs' share. Stephens' 68.1 coverage grade is a legitimate test. New England is a 7.5-point home favorite with a 43.5 total, a script that carries some risk of a run-heavy afternoon. He's a flex with a shaky floor.

Chris Olave (NO)

vs. Greg Newsome II (NYG)   •   Matchup: Safe

Olave is the heart of the Saints' passing game, with 39 catches on 54 targets for 537 yards, and he caught 4 of 6 for 46 yards last week, including an intercepted target in the fourth quarter. He ran 91% of the snaps and is a top-eight receiver on most boards. Newsome's 61.7 coverage grade is fair, nothing to fear. New Orleans is a 1.5-point road favorite with a 45.5 total, a tight game. Start him with confidence.

Malik Nabers (NYG)

vs. Quincy Riley (NO)   •   Matchup: Safe

Nabers had an enormous Week 5, catching 11 of 20 targets for 121 yards and a touchdown in the overtime loss to Washington, a 36% share of the targets. He's at 29 catches on 46 targets for 329 yards and 2 scores on the season. Riley's 54.9 coverage grade is a soft draw. New York is a 1.5-point home underdog with a 45.5 total, which should keep the volume high. He's a locked-in WR1.

Adonai Mitchell (NYJ)

vs. Christian Gonzalez (NE)   •   Matchup: Risky

Mitchell has missed three straight games with a finger injury and is listed as questionable, so he needs to show he's practicing before you trust him. When healthy he has 9 catches on 15 targets for 123 yards, but Garrett Wilson has soaked up the volume in his absence. Gonzalez's 64.7 coverage grade understates a corner many view as one of the best in the league, and he's back at practice after missing two games with a shoulder injury. New York is a 7.5-point road underdog with a 43.5 total. He's a speculative add at best until he practices.

Dontayvion Wicks (PHI)

vs. Will Lee III (CAR)   •   Matchup: Moderate

Wicks has been Philadelphia's top healthy wideout, with 17 catches on 28 targets for 260 yards, including 5 for 63 on 8 targets in the London loss to Jacksonville. DeVonta Smith is hopeful to return from his hamstring injury, which would trim Wicks' share. Lee's 62.3 coverage grade is a fair matchup. Philadelphia is a 1.5-point home underdog with a 40.5 total. He's a flex, and a better one if Smith sits.

DK Metcalf (PIT)

vs. Jacob Parrish (TB)   •   Matchup: Moderate

Metcalf has 19 catches on 37 targets for 225 yards and a touchdown, and last week was a quiet 3 for 12 on 4 targets as Aaron Rodgers checked down (5 air yards per attempt after 9.2 earlier in the season). With Michael Pittman on injured reserve and Roman Wilson out, Metcalf should see a bigger share of a thin Steelers receiver room. Parrish's 66.2 coverage grade is a legitimate test. Pittsburgh is a 2.5-point road favorite with a 39.5 total, the lowest on the slate. He's a volume-driven WR3.

Jaxon Smith-Njigba (SEA)

vs. Riley Moss (DEN)   •   Matchup: Safe

Smith-Njigba leads the league in receiving with 583 yards and 7 touchdowns on 37 catches, including 5 for 102 yards and a score in last week's loss to San Francisco. He's dealing with an ankle injury and has been limited in practice, but he finished the game and isn't expected to miss time. Moss's 58.2 coverage grade is a fair test. Seattle is a 2.5-point road favorite on Thursday night with a 40.5 total. Start him, but check the final report.

Mike Evans (SF)

vs. Amik Robertson (WAS)   •   Matchup: Moderate

Evans stepped up in a big way against Seattle, catching 7 of 10 targets for 113 yards and a touchdown, and he's at 24 catches for 326 yards and 3 scores. With Deebo Samuel out multiple weeks with a hamstring injury, he's San Francisco's clear No. 1 target. Robertson's 74.2 coverage grade makes this a tough draw. San Francisco is a 7.5-point home favorite on Monday night with a 50.5 total, which could mean more handoffs late. He's a solid WR2.

Ted Hurst (TB)

vs. Jamel Dean (PIT)   •   Matchup: Risky

Hurst has been a part-timer, with 8 catches on 16 targets for 128 yards and a touchdown, and he didn't draw a single target in last week's win over Dallas. Baker Mayfield (thumb) remains uncertain, so undrafted rookie Jalon Daniels may start again. Dean's 72.9 coverage grade makes this a tough draw. Tampa is a 2.5-point home underdog with a 39.5 total, the lowest on the slate. Avoid him.

Terry McLaurin (WAS)

vs. Deommodore Lenoir (SF)   •   Matchup: Moderate

McLaurin has been Washington's top receiver in the games he's played, with 14 catches on 26 targets for 203 yards and a touchdown, including 4 catches for 62 yards last week. Stefon Diggs (hamstring) is questionable, which could add to his target share. Lenoir's 60.8 coverage grade is a fair matchup. Washington is a 7.5-point road underdog on Monday night with a 50.5 total, which should force the Commanders to throw. He's a solid WR2.

Right Wide Receiver (RWR) vs. Left Cornerback (LCB)

Each team's outside receiver on the right side of the formation against the opponent's left cornerback.

Michael Wilson (ARI)

vs. Jaylen Watson (LAR)   •   Matchup: Moderate

Wilson is Arizona's clear No. 1 now that Marvin Harrison has been traded to Houston, and he's at 29 catches on 51 targets for 288 yards and a touchdown. Last week was quiet: 4 catches for 30 yards on 7 targets, so the yardage hasn't matched the volume. Watson's 73.4 coverage grade makes this a real test. The Cardinals are 12.5-point road underdogs with a 51.5 total, which means plenty of pass attempts, but also a likely trailing script that rarely helps efficiency. He's a volume-based WR2.

Jahan Dotson (ATL)

vs. Jaylon Johnson (CHI)   •   Matchup: Moderate

Dotson is the clear No. 2 behind Drake London in Atlanta, with 8 catches on 18 targets for 149 yards and a touchdown, and he turned 4 targets into 2 catches for 54 yards in the overtime loss to Baltimore. Johnson's 38.8 coverage grade is one of the lowest in the league, a real down year for a corner who graded out as the league's best in 2023. Atlanta is a 2.5-point home underdog with a 50.5 total, a good setup for volume. He's a deep flex if Michael Penix (ribs) plays.

DJ Moore (BUF)

vs. Eric Stokes (LV)   •   Matchup: Moderate

Moore re-aggravated his AC joint sprain in Week 4 and sat out last week's game against the Rams, and he's listed as questionable again. When healthy, he's a quality WR3 with 12 catches on 20 targets for 178 yards and a touchdown across four games. Stokes' 37.9 coverage grade is among the worst at the position, so the matchup couldn't be better. Buffalo is a 5.5-point road favorite with a 53.5 total, tied for the highest on the slate. Start him if he practices fully, and expect Keon Coleman and Khalil Shakir to benefit if he doesn't.

Luther Burden (CHI)

vs. Mike Hughes (ATL)   •   Matchup: Safe

Burden has settled in as a legitimate weekly option, with 23 catches on 35 targets for 266 yards and a touchdown, including 4 catches for 47 yards on 6 targets in the loss to Green Bay. Caleb Williams (hamstring) is close to returning, which would help the whole offense. Hughes' 37.5 coverage grade is one of the weakest marks in the league. Chicago is a 2.5-point road favorite with a 50.5 total, a game that should be competitive and high-scoring. Start him as a WR3 with upside.

Jerry Jeudy (CLE)

vs. Marlon Humphrey (BAL)   •   Matchup: Risky

Jeudy has been a disappointment, with 8 catches on 15 targets for 81 yards and no touchdowns, including 3 for 19 on 7 targets in the loss to the Jets. With KC Concepcion in the concussion protocol, he could see more looks, but efficiency has been the issue all season. Humphrey's 73.2 coverage grade makes this a tough draw. Cleveland is a 5.5-point home underdog with a 42.5 total. He's a stash at best.

CeeDee Lamb (DAL)

vs. Keisean Nixon (GB)   •   Matchup: Safe

Lamb is a top-10 receiver on the Week 6 boards despite a bruised quad that held him to 2 catches for 9 yards on 5 targets in the loss to Tampa Bay. The injury isn't considered serious, and Stephen Jones said Lamb will be ready to go for Sunday night. He's at 39 catches on 51 targets for 507 yards and 4 touchdowns, and Nixon's 64.2 coverage grade is a fair matchup. Dallas is a 1.5-point road underdog with a 53.5 total, a perfect shootout script. Start him with confidence and check the final report.

Jaylen Waddle (DEN)

vs. Devon Witherspoon (SEA)   •   Matchup: Risky

Waddle has been a letdown, with 18 catches on 31 targets for 204 yards and a touchdown, and he managed 2 catches for 19 yards on 5 targets against the Chargers. With Pat Bryant on injured reserve, he should be Denver's primary target, but Witherspoon's 72.0 coverage grade understates one of the league's most feared corners. Denver is a 2.5-point home underdog on Thursday night with a 40.5 total, the lowest-scoring environment on the board. He's a risky WR3.

Matthew Golden (GB)

vs. DaRon Bland (DAL)   •   Matchup: Safe

Golden has been a quiet star, with 24 catches on 44 targets for 397 yards and 2 touchdowns, and he posted 6 catches for 123 yards on 7 targets in the win over Chicago. He's a top-14 receiver this week. Bland's 45.0 coverage grade is one of the weaker marks in the league, and he's been dealing with an illness. Green Bay is a 1.5-point home favorite on Sunday night with a 53.5 total. Start him as a strong WR2.

Marvin Harrison (HOU)

vs. Travis Hunter (JAX)   •   Matchup: Risky

Harrison is in a new uniform after the Cardinals traded him to Houston for a second-round pick, but he still has just 5 catches on 13 targets for 85 yards and a touchdown this season. He reunites with college quarterback C.J. Stroud and is expected to make his debut, but Nico Collins is the alpha and Harrison will be learning on the fly. Hunter's 69.7 coverage grade is a real test. Houston is a 2.5-point road underdog in London with a 42.5 total. He's a stash with upside, not a start.

Keenan Allen (IND)

vs. Cor'Dale Flott (TEN)   •   Matchup: Moderate

Allen played last week after missing time with a groin injury, catching 5 of 9 targets for 45 yards, and he's at 18 catches on 29 targets for 145 yards and a touchdown. With Alec Pierce on injured reserve, he's a reliable target for Daniel Jones, though the ceiling is limited. Flott's 48.3 coverage grade is a soft matchup. Indianapolis is a 7-point home favorite with a 44.5 total, which carries some risk of a run-heavy script. He's a safe floor and a modest ceiling.

Jakobi Meyers (JAX)

vs. Derek Stingley (HOU)   •   Matchup: Moderate

Meyers has been efficient, with 15 catches on 18 targets for 202 yards and 2 touchdowns, though he was held to 2 catches for 37 yards on 3 targets in the win over Philadelphia. Stingley's 63.5 coverage grade is below his elite reputation, but he's still a top corner. Jacksonville is a 2.5-point home favorite in London with a 42.5 total, and the offense runs through Parker Washington first. He's a PPR flex with a safe floor.

Xavier Worthy (KC)

vs. Donte Jackson (LAC)   •   Matchup: Safe

Worthy comes off the bye as Kansas City's top receiver with Rashee Rice (hamstring) questionable and Tyquan Thornton out most of the season, and he's at 14 catches on 22 targets for 133 yards and a touchdown in four games. In his last game he caught 4 of 7 targets for 70 yards against the Raiders. Jackson's 54.7 coverage grade is a manageable matchup. Kansas City is an 8.5-point home favorite with a 42.5 total, which carries some risk of a run-heavy script. He's a strong WR3 with upside.

Puka Nacua (LAR)

vs. Max Melton (ARI)   •   Matchup: Safe

Nacua is back at full strength and in elite form: he caught 17 of 24 targets for 138 yards and a touchdown last week, and he's at 31 catches for 337 yards in three games. Melton's 66.3 coverage grade is a fair test for a receiver of this caliber. The Rams are 12.5-point home favorites with a 51.5 total, so a big lead could mean fewer late throws, but Nacua's volume is extraordinary. Start him every week.

Cody White (LV)

vs. Christian Benford (BUF)   •   Matchup: Risky

White has scored 3 touchdowns on just 7 catches and 14 targets, which is the definition of unsustainable, and he caught 2 for 44 yards last week. Jalen Nailor (concussion) expected to practice would eat into his snaps again. Benford's 51.6 coverage grade is fair. Las Vegas is a 5.5-point home underdog with a 53.5 total, so the offense will be throwing. He's a touchdown-or-nothing dart.

Efton Chism (NE)

vs. Azareye'h Thomas (NYJ)   •   Matchup: Risky

Chism has emerged as a useful secondary option, with 9 catches on 13 targets for 98 yards and a touchdown, including 5 catches for 57 yards on 6 targets last week. Mack Hollins is on injured reserve, but A.J. Brown's practice window opened Wednesday and he's pushing to play Sunday, which would push Chism down the pecking order. Thomas' 74.4 coverage grade is one of the tougher draws on the slate. New England is a 7.5-point home favorite with a 43.5 total. He's a deep-league flex.

Malachi Fields (NYG)

vs. Kool-Aid McKinstry (NO)   •   Matchup: Risky

Fields has been a part-timer, with 10 catches on 17 targets for 146 yards and a touchdown, and he caught just 2 passes for 20 yards in the overtime loss to Washington as Malik Nabers and Isaiah Likely dominated the targets. McKinstry's 51.7 coverage grade is a soft matchup, but the role is the problem. New York is a 1.5-point home underdog with a 45.5 total. He's a deep dart.

Garrett Wilson (NYJ)

vs. Carlton Davis III (NE)   •   Matchup: Moderate

Wilson is the engine of the Jets' offense, with 31 catches on 42 targets for 374 yards and 3 touchdowns, and he caught 7 of 11 targets for 104 yards and a 32-yard score in the win over Cleveland, a 34% share of the targets. Davis' 79.6 coverage grade is one of the best at the position, though he's dealing with a neck injury and wasn't slated to practice Wednesday. New York is a 7.5-point road underdog with a 43.5 total, which means pass volume. He's a strong WR2 despite the corner.

DeVonta Smith (PHI)

vs. Akayleb Evans (CAR)   •   Matchup: Moderate

Smith missed the last two games with a hamstring injury, and Nick Sirianni says he's hopeful to have him back this week, so check the practice reports. Before the injury, he had 19 catches on 27 targets for 235 yards and a touchdown, and Jalen Hurts' completion rate is 65.5% with him on the field compared to 48.6% without. Evans' 43.0 coverage grade is a soft matchup. Philadelphia is a 1.5-point home underdog with a 40.5 total. If he's cleared, he's a WR2.

Germie Bernard (PIT)

vs. Zyon McCollum (TB)   •   Matchup: Moderate

Bernard stepped into a starting role last week with Michael Pittman on injured reserve and Roman Wilson hurt, running a route on 78% of dropbacks and catching 6 of 9 targets for 80 yards. He now has 13 catches on 20 targets for 140 yards on the season and a starting job. McCollum's 59.2 coverage grade is a fair matchup. Pittsburgh is a 2.5-point road favorite with a 39.5 total, the lowest on the slate. He's a flex with room to grow.

Rashid Shaheed (SEA)

vs. Pat Surtain II (DEN)   •   Matchup: Moderate

Shaheed has 9 catches on 19 targets for 96 yards, and he managed 2 for 23 on 4 targets in the loss to San Francisco. Pat Surtain II (ankle) missed last week's game, hasn't practiced this week, and is expected to sit, so this matchup should be softer than his reputation suggests. Seattle is a 2.5-point road favorite on Thursday night with a 40.5 total. He's a big-play dart with a decent matchup.

Emeka Egbuka (TB)

vs. Asante Samuel Jr. (PIT)   •   Matchup: Moderate

Egbuka has 21 catches on 33 targets for 192 yards and a touchdown, and he caught 6 of 9 targets for 38 yards in last week's win over Dallas with rookie Jalon Daniels at quarterback. Baker Mayfield (thumb) remains uncertain. Samuel's 51.4 coverage grade is a soft matchup. Tampa is a 2.5-point home underdog with a 39.5 total, a low-scoring game. He's a WR3 who has to be trusted on volume alone.

Carnell Tate (TEN)

vs. Charvarius Ward (IND)   •   Matchup: Moderate

Tate has been the target leader in Tennessee's offense, with 23 catches on 37 targets for 274 yards, but he caught just 1 of 5 targets for 6 yards in the 26-3 loss to Houston. Ward's 58.9 coverage grade is a fair matchup. Tennessee is a 7-point road underdog with a 44.5 total, which means pass volume, but the offense has been struggling. He's a flex with a bounce-back opportunity.

Slot Receiver vs. Nickel Corner

Each team's primary slot receiver against the opponent's nickel corner.

Kendrick Bourne (ARI)

vs. Josh Wallace (LAR)   •   Matchup: Moderate

Bourne has been a sneaky PPR piece for Arizona, with 17 catches on 22 targets for 178 yards, and he caught 5 of 8 targets for 70 yards last week. With Marvin Harrison traded to Houston, the receiver room is thinner, and Bourne and Michael Wilson are the main options for Jacoby Brissett. Wallace's 61.3 coverage grade is a fair matchup. Arizona is a 12.5-point road underdog with a 51.5 total, so the Cardinals should be throwing a lot. He's a deep PPR flex.

Zay Flowers (BAL)

vs. Myles Harden (CLE)   •   Matchup: Safe

Flowers is a top-tier receiver with 26 catches on 31 targets for 405 yards and 2 touchdowns in four games, and he caught 8 of 9 targets for 53 yards last week with Tyler Huntley at quarterback. Lamar Jackson (ankle) has a realistic chance to return, which would help his ceiling, and Flowers has been a must-start either way. Harden's 55.3 coverage grade is a fair matchup. Baltimore is a 5.5-point road favorite with a 42.5 total. Start him with confidence.

Khalil Shakir (BUF)

vs. Taron Johnson (LV)   •   Matchup: Moderate

Shakir has been a steady slot piece, with 18 catches on 26 targets for 256 yards, including 3 catches for 80 yards on 3 targets against the Rams. His role grows if DJ Moore (shoulder) misses another game. Johnson's 58.2 coverage grade is a fair matchup. Buffalo is a 5.5-point road favorite with a 53.5 total, tied for the highest on the slate. He's a solid PPR WR3.

Jalen Coker (CAR)

vs. Cooper DeJean (PHI)   •   Matchup: Moderate

Coker is expected to return from his quad injury after missing Week 4 and the bye, and he has 18 catches on 22 targets for 222 yards and 2 touchdowns in three games. He was the leading receiver before Tetairoa McMillan's big day in his absence. DeJean is one of the best young slot corners in the league, which makes this a real test. Carolina is a 1.5-point road favorite with a 40.5 total, the second-lowest on the slate. He's a good flex if he's cleared.

Kalif Raymond (CHI)

vs. Billy Bowman Jr. (ATL)   •   Matchup: Moderate

Raymond has been a PPR surprise with 24 catches on 27 targets for 226 yards and a touchdown, but last week he caught just 3 passes for 6 yards on 4 targets in the loss to Green Bay. Caleb Williams (hamstring) is close to returning, which would help the whole offense. Bowman's 58.8 coverage grade is a fair matchup. Chicago is a 2.5-point road favorite with a 50.5 total. He's a floor-based flex.

Isaiah Bond (CLE)

vs. Kyle Hamilton (BAL)   •   Matchup: Risky

With KC Concepcion (concussion) expected to miss time, rookie Isaiah Bond could step into a larger role after catching 3 of 7 targets for 74 yards last week. He has only 5 catches on 9 targets for 86 yards on the season, so this is a speculative add. Kyle Hamilton is one of the league's most versatile defenders, which makes this a hard matchup. Cleveland is a 5.5-point home underdog with a 42.5 total. He's a deep-league dart.

Ryan Flournoy (DAL)

vs. Javon Bullard (GB)   •   Matchup: Moderate

Flournoy is a handcuff to watch: he posted a season-high 90 yards on 3 catches (4 targets) last week when CeeDee Lamb missed snaps with a quad bruise, and he has at least four targets in every game. He's at 16 catches on 27 targets for 194 yards on the season. Dallas is a 1.5-point road underdog on Sunday night with a 53.5 total, a perfect shootout script. He's a stash, and a spot start if Lamb is limited.

Xavier Hutchinson (HOU)

vs. Jourdan Lewis (JAX)   •   Matchup: Moderate

Hutchinson has settled into a part-time role with 16 catches on 31 targets for 231 yards, and he caught 4 of 5 targets for 65 yards in the win over Tennessee. Marvin Harrison's arrival could cut into his snaps. Lewis' coverage grade of 59.4 is fair. Houston is a 2.5-point road underdog in London with a 42.5 total. He's a deep PPR flex.

Josh Downs (IND)

vs. Marcus Harris (TEN)   •   Matchup: Moderate

Downs has been Indianapolis' most reliable receiver, with 20 catches on 34 targets for 249 yards, though he caught just 3 of 6 for 47 in the loss to Pittsburgh. Alec Pierce is on injured reserve and Darius Slayton (knee) is questionable, so Downs should see steady volume. Harris' 67.8 coverage grade is a legitimate test. Indianapolis is a 7-point home favorite with a 44.5 total. He's a solid WR3.

Parker Washington (JAX)

vs. Jalen Pitre (HOU)   •   Matchup: Safe

Washington is one of the stars of the week, a top-three receiver on some boards after catching 6 of 9 targets for 124 yards and 2 touchdowns in London, and he leads Jacksonville with 22 catches for 352 yards and 4 scores. He's the clear alpha in this offense. Pitre is a veteran slot defender who can be beaten with route running. Jacksonville is a 2.5-point home favorite in London with a 42.5 total. Start him.

Rashee Rice (KC)

vs. Tarheeb Still (LAC)   •   Matchup: Moderate

Rice is off the bye with a hamstring injury that Ian Rapoport called relatively minor, and the week off should help. He's at 13 catches on 17 targets for 190 yards and a touchdown in four games, but he played just 6 snaps before leaving in Week 4. Still's 77.5 coverage grade is one of the best at the position. Kansas City is an 8.5-point home favorite with a 42.5 total. Check his practice status, then start him if he's cleared.

Ladd McConkey (LAC)

vs. L'Jarius Sneed (KC)   •   Matchup: Moderate

McConkey was active last week but didn't play a snap with his foot injury, and he's listed as questionable again. When healthy he's the engine of this offense (12 catches on 17 targets for 183 yards and a touchdown), but Justin Herbert threw for just 121 yards without him. Sneed's 28.6 coverage grade is one of the lowest in the league, a dream matchup if he plays. Los Angeles is an 8.5-point road underdog with a 42.5 total. Check practice reports before locking him in.

Konata Mumpfield (LAR)

vs. Garrett Williams (ARI)   •   Matchup: Risky

Mumpfield has been a minor piece in a crowded Rams passing game, with 6 catches on 14 targets for 112 yards and a touchdown, and he didn't draw a target last week. Nacua's 24 targets show where the volume goes. The Rams are 12.5-point home favorites with a 51.5 total, and a big lead means even fewer throws. He's not worth a roster spot.

Tre Tucker (LV)

vs. Dee Alford (BUF)   •   Matchup: Safe

Tucker is Las Vegas' top receiver, with 19 catches on 28 targets for 274 yards and a touchdown, and he caught 4 of 5 for 41 yards last week. Jalen Nailor (concussion) is expected to practice, but the target share runs through Tucker. Alford's 41.8 coverage grade is a soft matchup. Las Vegas is a 5.5-point home underdog with a 53.5 total, a shootout script. He's a strong WR3.

DeMario Douglas (NE)

vs. Jarvis Brownlee Jr. (NYJ)   •   Matchup: Moderate

Douglas scored twice last week, catching 4 of 5 targets for 65 yards and 2 touchdowns, and he's at 13 catches on 22 targets for 147 yards and 2 scores. A.J. Brown (ankle) opened his practice window Wednesday and is trying to return, which would cut into the targets. Brownlee's 63.9 coverage grade is a fair matchup. New England is a 7.5-point home favorite with a 43.5 total. He's a touchdown-dependent flex.

Devaughn Vele (NO)

vs. Dru Phillips (NYG)   •   Matchup: Moderate

Vele has been a real PPR piece for the Saints, with 25 catches on 37 targets for 252 yards and 2 touchdowns, and he caught 4 of 6 for 26 yards last week. He's locked into the No. 2 role behind Chris Olave. Phillips' 64.7 coverage grade is a fair test. New Orleans is a 1.5-point road favorite with a 45.5 total. He's a safe WR3.

Isaiah Williams (NYJ)

vs. Marcus Jones (NE)   •   Matchup: Risky

Williams has been a part-timer, with 11 catches on 14 targets for 151 yards and a touchdown, but he saw just 2 targets last week as Garrett Wilson ate up the volume. Adonai Mitchell's possible return would push him down further. Jones' 61.4 coverage grade is a fair matchup, but the role is the issue. New York is a 7.5-point road underdog with a 43.5 total. He's a deep dart.

Makai Lemon (PHI)

vs. Tre'von Moehrig (CAR)   •   Matchup: Risky

Lemon has been a disappointment for a first-round pick, with 15 catches on 22 targets for 108 yards and no touchdowns, including 5 catches for 43 yards on 7 targets last week. With DeVonta Smith likely to return, his targets shrink. Moehrig is a physical safety playing in the slot, which makes this a tough draw. Philadelphia is a 1.5-point home underdog with a 40.5 total. He's a bench candidate.

Cooper Kupp (SEA)

vs. Ja'Quan McMillian (DEN)   •   Matchup: Risky

Kupp has been a complementary piece, with 11 catches on 15 targets for 129 yards and a touchdown, and he caught 2 for 15 on 3 targets against San Francisco as Jaxon Smith-Njigba dominated the offense. McMillian's 61.1 coverage grade is a fair matchup. Seattle is a 2.5-point road favorite on Thursday night with a 40.5 total, a low-scoring spot. He's a boom-or-bust flex.

Jordan Watkins (SF)

vs. Nick Cross (WAS)   •   Matchup: Risky

With Deebo Samuel (hamstring) expected to miss multiple weeks, Jordan Watkins is one of the candidates to step into San Francisco's WR2 role next to Mike Evans, along with Brandin Cooks and Jacob Cowing. He has just 2 catches on 2 targets for 60 yards in three games, so this is a speculative add. San Francisco is a 7.5-point home favorite on Monday night with a 50.5 total, which carries some risk of a run-heavy script. He's a deep-league dart.

Chris Godwin (TB)

vs. Jalen Ramsey (PIT)   •   Matchup: Moderate

Godwin has 19 catches on 21 targets for 179 yards and no touchdowns, a PPR floor profile that has held up even with rookie Jalon Daniels at quarterback (3 catches for 37 yards last week). Baker Mayfield's thumb injury remains uncertain. Jalen Ramsey is a veteran slot defender who is tough to beat. Tampa is a 2.5-point home underdog with a 39.5 total, the lowest on the slate. He's a PPR flex.

Wan'Dale Robinson (TEN)

vs. Justin Walley (IND)   •   Matchup: Safe

Robinson caught 6 of 7 targets for 53 yards in the 26-3 loss to Houston, and he's at 22 catches on 30 targets for 176 yards and 2 touchdowns. Walley's 50.9 coverage grade is a soft matchup. Tennessee is a 7-point road underdog with a 44.5 total, which means he should see volume again. He's a safe PPR WR3.

Stefon Diggs (WAS)

vs. Upton Stout (SF)   •   Matchup: Moderate

Diggs missed last week's overtime win over the Giants with a hamstring injury and is listed as questionable, but he has 18 catches on 31 targets for 170 yards and 3 touchdowns in four games. Upton Stout's 47.5 coverage grade is a soft matchup. Washington is a 7.5-point road underdog on Monday night with a 50.5 total, which should force the Commanders to throw. Check his practice status and start him if he's cleared.