Jahmyr Gibbs is considered the best RB in football by many fans, and Josh Allen is the best QB in the game. So, when we get to see them kick off the Week 2 slate in primetime fashion, what more could we ask for? Well, how about some NFL best bets for Thursday Night Football? Getting to make some NFL picks on Lions vs. Bills is as good as it gets, especially when it can help with your fantasy action at the same time.

In fact, we’ll also help more than just NFL predictions instantly become more valuable with today’s $1,000 Fanatics Sportsbook promo code bonus!

🔥 NFL Week 2 Thursday Night Football Best Bets, Expert Picks & Predictions, 9/17

While Jahmyr Gibbs helped the Lions get out to a rather commanding lead over the New Orleans Saints on Sunday, they were still forced into overtime. Speaking of which, we cashed our Chris Olave pick from that game, so in addition to the top pick from our NFL best bets for Thursday Night Football here, be sure to also check out our NFL expert picks.

As for the teams here, the Bills had a huge 36-31 victory over the Houston Texans in what was one of the games of the weekend. Staying right on brand, we saw Josh Allen both throw for two touchdown passes AND run for two touchdowns. Taking on Superman in such a quick turnaround makes a Detroit bounce back even more difficult.

That’s why we see Buffalo favored, and if you want an overall game-market approach, just check out our Lions vs. Bills predictions. As for another approach, we’ll keep our NFL best bets for Thursday Night Football rolling with a top pick below!

 

 

 

🏉 Lions vs. Bills Best Bet for NFL Week 2 Thursday Night Football: Detroit Team Total Over 23.5 (-110 at Fanatics)

Once you check out the predictions above, you’ll see what side of this matchup we’re on, and while breaking things down, you’ll also see that this is the highest total of the season thus far. Sure, it’s only Week 2, but the oddsmakers are expecting a shootout with a 53.5 over/under, and that is worth noting for our NFL best bets for Thursday Night Football.

We also expect both sides to do their fair share of scoring, and as you can see, we believe that this Buffalo defense can be exploited. While everyone is talking about how impressive it was to put up 36 points on the Texans defense - and it was - they also allowed 31 points to a Houston team that is built around that defense, not lighting up the scoreboard.

You’ll also see that beyond our NFL best bets for Thursday Night Football, touchdown props for this game have multiple guys with shorter than +100 odds to score; that again suggests plenty of scoring to be done. Furthermore, while these interconference teams don’t meet every year, the past two matchups finished 28-25 and 48-42.

So, overall, we’re expecting another close game with plenty of points, and the top pick from our NFL best bets for Thursday Night Football is Detroit’s team total over 23.5 (-110 at Fanatics). 

🔢 Best NFL Player Prop Bets & Picks Today for Thursday Night Football

We’ve noted star players right from the rip, so it’s only fitting that we share some other NFL picks to consider. Here are some popular Lions vs. Bills player props for TNF at Fanatics Sportsbook:

Anytime Touchdown:

Passing Yards (Over/Under):

  • Jared Goff: Over 265.5 (-120) vs. Under 265.5 (-105)
  • Josh Allen: Over 252.5 (-115) vs. Under 252.5 (-115)

Rushing Yards (Over/Under):

Receiving Yards (Over/Under):

 

 

 

📊 Fantasy Alarm NFL Best Bets Record 

One last thing before we hook you up with a $1,000 Fanatics promo code bonus to go with our NFL best bets for Thursday Night Football. Week 1 wasn’t perfect, but we’re still in a solid position to have as great of a season as last year!

  • Overall record: 19-16
  • Units: 0.26u
  • ROI: 0.74%

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