NFL Week 12 betting got off to a real nice start for us with the Thanksgiving Day slate and after ignoring the New York Jets/Miami Dolphins game on Black Friday, we're ready to get back to our football bets this week. Hopefully, by the time you've opened this article, you've studies the NFL Injury Report and checked out all the Fantasy Alarm content pertinent to laying some action on games this weekend. It's very important that you stay completely up to date on all the latest NFL news so you don't miss anything and end up making the wrong bets. I literally just had a conversation with someone who was asking about Puka Nacua prop bets and had no idea that Cooper Kupp was expected back this week. I'm not sure I understand why you would put your hard-earned dollars on the line without doing the proper research. I do it before I post my picks here, but I'm also not making picks for every single game, so do yourself a favor and keep up to date with everything. You'll be a better bettor in the end. 



NFL Week 12 Best Bets

Carolina Panthers vs Tennessee Titans

It's a battle of bottom-feeders here as the one-win Panthers head into Tennessee to take on the 3-7 Titans. Yes, it can be a dangerous proposition to bet on bad teams, but this is more about me betting on Mike Vrabel than it is on the actual players. Vrabel has been an outstanding coach and typically gets the most out of his players. He's had some quarterback issues and injuries on both sides of the ball, but I'm looking at him in a home game he does not want to lose. You can say that about any coach, but Vrabel is one of those “no one comes into our house and pushes us around” guys and that should play this week. It also helps that the Titans are 3-1 at home this season and 3-1 against the spread in those games. I think he gets his team back to the basics and we see a heavy run scheme with a lean on those players who have performed well for him in the past, i.e. Derrick Henry.

Pick: Titans -3.5 (-110)

New England Patriots vs New York Giants

Remember last week when we were laughing at the low game totl for the Cleveland Browns/Pittsburgh Steelers game and how we were still so bullish on the under? Yeah, we're all about that again here. Bill Belichick knows all of Brian Daboll's tendencies and there is just no way his scheme doesn't tear apart Tommy DeVito. He'll also focus on stopping Saquon Barkley. As for the Patriots offense, we still don't know if it's Mac Jones or Bailey Zappe under center. Not that it really matters as we expect them to have difficulty scoring no matter who plays. 

Pick: Patriots/Giants under 34 (-110)

Los Angeles Rams vs Arizona Cardinals

We've got an innovative coach in Sean McVay and a healthy Matthew Stafford with all of his weapons at his disposal, including the return of Kyren Williams. Cooper Kupp (ankle) is expected to play and Puka Nacua was removed from the injury report. The Cardinals defense is absolutely atrocious and even though head coach Jonathan Gannon is a bit of a defensive wizard, he just doesn't have the personnel to shut down this Rams offense. On the other side, Kyler Murray looks rock-solid in his return and while they're a little banged-up in the receiving corps, Murray will still have Trey McBride, Greg Dortch and Marquise Brown to target. Not to mention James Conner to fall back on. I originally bet the over when it was at 44.5 and it's now gone up to 45.5. I'm still good betting that over.

Pick: Rams/Cardinals over 45.5 (-110)

Buffalo Bills vs Philadelphia Eagles

We've got a potential Super Bowl match-up here between the Bills and Eagles and while I usually just like to watch games like this and not worry about betting it, I've decided to throw a unit down and have some skin in the game. I have a feeling most will look to the Eagles after logging a road win against the Chiefs, but if you actually watched that game you probably know that they should have lost. Patrick Mahomes was en route to bringing them back and if it wasn't for a series of drops, the Chiefs would have won. I'm not a fan of this Eagles secondary and now that Joe Brady is the one calling the offensive shots for Buffalo, I am much more bullish on their passing attack. Buffalo is not in as bad of shape as some might think and I love getting points here.

Pick: Buffalo Bills +3 (-110)

Favorite NFL Week 12 Player Props:

**all lines & odds courtesy of BetMGM