The NBA rolls into November 4th, 2025, with a loaded six-game slate headlined by Giannis Antetokounmpo, Paolo Banchero, Jalen Johnson, and Scottie Barnes. Here are our sharpest PrizePicks NBA Top Picks to crush these marquee matchups and kick off the 2025-26 season.

PrizePicks NBA Picks Today: Tuesday, 11/4; NBA DFS Projections

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Collin Sexton PrizePicks NBA Pick: More Than 6.5 Assists

With LaMelo Ball officially ruled out, Collin Sexton will once again operate as the team’s starting point guard. Sexton, last game, had a team-leading 14 potential assists, 12 actual assists, 54 passes made, and 72 passes received. All four of those categories were team-leading numbers. This spot against the Pelicans is the 29th-ranked defense in the league.

 

 

 

Nikola Vucevic PrizePicks NBA Pick: More Than 33.5 Points+Rebounds+Assists

This matchup for Nikola Vucevic is quite good. Joel Embiid is not as mobile as he was pre-knee injury, but he has been unable to guard people defensively. Vucevic, over the last five games, has 12 rebounds and 17.8 potential rebounds, 4.8 assists, and 6.4 potential assists as well. On the year, he’s averaged 19.3 PPG too, and without Coby White, he’ll continue to be the Bulls' nightly number two option offensively.
 

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