Welcome to Fantasy Alarm's MLB DFS picks and daily fantasy playbook for Sunday, September 27th, otherwise known as the LAST day of the MLB regular season. Our MLB DFS projections combine advanced pitching metrics, platoon splits, strikeout prop data, and ownership positioning to identify the sharpest plays on every slate. Whether you are targeting DFS Projections, running lineups through our DFS Optimizer, tracking ownership trends, or checking confirmed lineups, Fantasy Alarm has the tools to sharpen your edge. 

Today's slates have multiple different directions with some quality hitters in Elly De La Cruz, Yordan Alvarez, Jackson Chourio, and Miguel Vargas all digging into the box. This MLB DFS playbook covers every key position on DraftKings and FanDuel with our best MLB DFS picks for today.

Slate: 13-Games | Lock Time: 3:05 pm ET on DK, Sunday, September 27th, 2026

Vegas Totals: HOU/ATH (highest-projected game), CIN/TOR (second-highest game total), COL/CWS & CLE/KC (tied for third-highest game total)

Highest K-Projections: Logan Gilbert 7.5 O/U (+111), Jacob Misiorowski 6.5 O/U (-116), Zack Wheeler 6.5 O/U (+116), Jared Jones 5.5 O/U (-144), Max Scherzer 5.5 O/U (+115), Yusei Kikuchi 5.5 O/U (+118)

MLB Weather Today, 9/27

Mets vs Nationals - Rain in the forecast that they'll try playing through.

Orioles vs Yankees - Rain in the forecast that they'll try playing through.

Rays vs Phillies - Rain in the forecast that they'll try playing through.

MLB DFS Lineup Picks: Starting Pitchers

MLB DFS Top Pitchers

MLB DFS Value Pitchers

Top Options For Strikeouts

K-prop lines and value ratings are incorporated below for DFS and prop context. These are the arms building the highest strikeout ceilings on the 9-game slate.

Our model identifies these arms as the highest-ceiling plays for Alt-K lines today:

Jacob Misiorowski: 38.2% K% (13.1 K/9)

Zack Wheeler: 30.2% K% (10.9 K/9)

Jared Jones: 29.4% K% (10.9 K/9)

Logan Gilbert: 26.7% K% (9.7 K/9)

Parker Messick: 26.1% K% (9.4 K/9)

Best Odds For A Win

The following MLB DFS picks offer a combination of favorable win odds, sustainable ERA and xFIP metrics, and soft opponent matchups. Each carries K-prop lines worth noting alongside their DFS value at reduced ownership relative to the top tier.

MLB DFS Lineup Picks: Stacks & Hitters

MLB DFS Top Hitters

MLB DFS Value Hitters

MLB DFS Top Stacks

Primary Stack: Houston Astros vs Seth Johnson (ATH RHP)

Targets: Yordan Alvarez, Jeremy Pena, Isaac Paredes, Jose Altuve, Christian Walker, Lucas Spence

Primary Stack: Cincinnati Reds vs Max Scherzer (TOR RHP)

Targets: Elly De La Cruz, JJ Bleday, Hector Rodriguez, Carlos Jorge, Eugenio Suarez

Primary Stack: Cleveland Guardians vs Daniel Lynch (KC LHP)

Targets: Jo Adell, Angel Martinez, Brayan Rocchio, Jose Ramirez, Chase DeLauter

“Contrarian” Stack: Toronto Blue Jays vs Brandon Williamson (SDP RHP)

Targets: Kazuma Okamoto, Alejandro Kirk, George Springer, Vladimir Guerrero, Charles McAdoo

“Contrarian” Stack: Chicago White Sox vs Kyle Freeland (COL LHP)

Targets: Miguel Vargas, Chase Meidroth, Randal Grichuk, Brenton Doyle, Tommy Pham

MLB DFS Lineups: Core MLB DFS Hitters & Pitchers

The "Chalk" (Popular)

The "Pivot" (Low

Owned)

Wrobleski (SP, chalk)Jones (SP, lower owned)
Astros (Chalk)Reds (pivot stack)
Genao + Ramirez (chalk)De La Cruz + Carlos Jorge (lower owned)

 

 

 

 

 

 

 

The foundation for every MLB DFS lineup you build today. These are the core MLB DFS picks by position across DraftKings and FanDuel.

  1. Logan Gilbert (SP1)
  2. Jared Jones (SP2)
  3. Yordan Alvarez (Core Bat)
  4. Elly De La Cruz (Core Bat)
  5. Isaac Paredes (Core Bat)
  6. Carlos Jorge (Core Value Bat)
  7. Lucas Spence (Core Value Bat)

Player Pool

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Stacks

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