MLB Home Run Picks Today: Best HR Predictions for May 10th, 2026
After one streak of MLB home run picks ends, it never seems to take us more than a day (maybe two) to begin a new one. That’s what we had yesterday with Colson Montgomery going deep for us! Now Sunday, we’ve got all-day action on the diamond to enjoy, so there’s no time to waste locking in the best MLB home run predictions for today!
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⚾ Top MLB Home Run Picks for Today
It was a toss-up between Colson Montgomery and Miguel Vargas for us yesterday, and they both hit dingers (Vargas twice)! We say that to note that it’s always worth checking out the reasoning behind our best MLB home run picks today, and of course, our MLB expert picks!
- Austin Riley: +456 at Novig Sportsbook
- Gary Sanchez: +525 at bet365 Sportsbook
- Nathaniel Lowe: +520 at BetMGM Sportsbook
🔥 Best Matchups for Home Runs Today, 5/10: Ballpark Factors & Weather Impact
You’ve got the names, but why? As always, we’ll first refer you to our MLB weather report, as wind and rain absolutely play a role - we even had snow in Colorado recently! Beyond the uncontrollable are other factors to make the best MLB home run picks, such as lefty/righty splits, barrel/hard hit rates and more!
Austin Riley (+456)
We were tempted to take a hitter in the Braves vs. Dodgers game last night with lefty Blake Snell making his season debut, but as it turns out, we’re glad we didn’t. Atlanta did what we expected (five runs in the first two innings), but none came by the long ball. Well, as you can see, we have that changing to lead off our best MLB home run picks for today.
Atlanta doesn’t get Snell again, but they do get Justin Wrobleski - another lefty. We expected big things yesterday because the Braves smash lefties, so this is another smash spot for a homer. The only issue here is the pick-your-poison scenario. We’re going to trust the career-long success of the third baseman rather than the smaller sample sizes in this case.
Therefore, we’re leading off our best MLB home run picks for today with Austin Riley to hit a HR (+456 at Novig Sportsbook).
Gary Sanchez (+525)
The next name that we’ve got for you is one that is likely not on anyone else’s radar today, so we’re getting some solid odds here. It’s not quite longshot territory, but we’re backing Milwaukee’s DH in a bit of a revenge spot. It’s been a while since Gary Sanchez was with the Bronx Bombers, but that’s not the primary reason he’s part of our best MLB home run picks today.
He’s taking on Carlos Rodon making his season debut. In other words, the same situation as to why we picked on Snell last night. That’s because Rodon is also a lefty, which is where Sanchez has thrived this season. He’s hitting .400 against such pitching with a .760 slugging percentage, so we’ve got Gary Sanchez to hit a HR (+525 at bet365 Sportsbook) as part of our top MLB home run picks.
Nathaniel Lowe (+520)
How could we not wrap things up without the Great American Ball Park? Look, we’ll admit it’s been a weird series in Cincinnati this weekend with 10-0 and 3-1 games, but with Kai-Wei Teng opening for Houston and Andrew Abbott starting for Cincinnati, this is a matchup that absolutely has to be part of our best MLB home run picks for today.
Both teams have great matchups, but to lock in just one guy, we’re going to go with Nathaniel Lowe. Since we think plenty of guys have great opportunities (Sal Stewart, Yordan Alvarez, Christian Walker and more), why not get better value? After all, Lowe has hit all six of his homers vs. righties this season, such as Teng.
Along with Houston’s terrible bullpen, especially in terms of HRs, we’ll add to our best MLB home run picks for today with Nathaniel Lowe to hit a HR (+520 at BetMGM Sportsbook).
🚀 Longshot Home Run Picks Today
Those are our favorite three spots overall, but how about an even bigger payout? That’s what our best MLB home run longshot pick for today is here for, which is…
We’re headed to Camden Yards to fade the fading O’s, especially their bullpen. They’ve allowed 20 homers this season, and starter Chris Bassitt is already a solid matchup for this lefty. So, we’ve got the former New York Met as our best MLB home run longshot pick for today!
💲 Today’s Best MLB Home Run Parlay
As you’re about to see, we’ve pieced together names that are different from our first three targets, but are still part of the same matchups. So, here is our best MLB home run parlay for today:
Mix and match some of those guys with our original three or piece things together however you see fit. No matter your approach, make the most of our best MLB home run picks for today to close out your weekend with some huge payouts!
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