All Week 15 matchups Data: Fantasy Alarm · SportRadar

2026 NFL · Week 15 · Thursday Night Football

49ers at Chargers

Week 15 fantasy football matchup analysis: odds and implied totals, unit-vs-unit edges, position matchups, usage, practice reports and weather.

Away · 7–1

49ers

San Francisco

Spread

+2.5

Spread: +2.5
Implied pts: 22.5
Moneyline: +114
Win prob: 44.9%

Thu · Dec 17

8:15 PM ET

SoFi Stadium

Over / Under

47.5

Projected score · All-Pro

Home · 0–8

Chargers

Los Angeles

Spread

-2.5

Spread: -2.5
Implied pts: 25.0
Moneyline: -135
Win prob: 55.1%