Thanksgiving 2025 brings three outstanding games and some of the most mispriced PrizePicks lines you’ll see all season. With division races on the line, massive totals, and key injuries creating monster usage bumps, we’re attacking two plays that are basically printing.

Best PrizePicks NFL Pick'em for Thanksgiving Day

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Kareem Hunt PrizePicks Thanksgiving Day Pick: Anytime TD

Hunt has scored a rushing TD in four of his last five games and five of his last seven. Even with Pacheco returning this week, Hunt remains the short-yardage and goal-line hammer for the NFL’s best red-zone offense. Dallas has surrendered 13 rushing TDs this season (tied-6th most) and multiple rushing scores in four separate games. Kansas City is favored and should lean on the run late. Hunt’s touchdown equity is still elite.
 

 

 

Christian Watson PrizePicks Thanksgiving Day Pick: Higher than 24.5 Yards - Longest Receptions

Watson’s longest reception has hit the over 24.5 yards in three of the last five games. He’s getting deep shots every single week from Jordan Love, and Detroit has given up the 9th-most 20+ yard completions while ranking bottom-10 in explosive pass rate allowed. One deep ball, and this one is over.
 

 

 

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