While the San Francisco 49ers and Los Angeles Rams were down in Australia for the season’s first Thursday Night Football game, the Los Angeles Chargers are holding down the fort at SoFi Stadium. They’re doing so by hosting the now Kyler Murray-less Arizona Cardinals, who are hoping that #3 overall pick Jeremiyah Love can be the spark that they need. As we get set to watch that play out, we’ve got our best Cardinals vs. Chargers predictions for Week 1.

We’ve also got more than just a best bet from our Cardinals vs. Chargers picks, which is a guaranteed Splash Sports promo code bonus!

🔥 Cardinals vs. Chargers Predictions for NFL Week 1, Sunday, 9/13

Whether you’re in on Jeremiyah Love being a worthy top-three pick or not, the fact remains that Arizona has the lowest win total this season at 3.5; the Cardinals vs. Chargers odds reflect that as well. LA opens as monster favorites, with their young RB, Omarion Hampton, being extremely popular among fantasy football pundits.

Similarly, we saw Ladd McConkey gain even more popularity last season, and that was even with Justin Herbert being banged up for a portion of it. So, saying that LA should win the game isn’t exactly groundbreaking in terms of Cardinals vs. Chargers predictions, but there is always value to be found.

At first glance, some passing props look great, some rushing props look even more enticing, and just across the board, a ton of LA markets jump off the page. So, rather than getting burned in a pick-your-poison scenario, we’re going to take advantage of a key number with the best bet from our Cardinals vs. Chargers predictions.

🏅 Cardinals vs. Chargers Expert Pick: Los Angeles -9.5 (Pair w/ Splash Sports Contests)

The key number we’re talking about is 10. It may not be as crucial as three or seven, but it’s not far from it. That’s why it’s important to find this line at 9.5 rather than where it opened, which was at 10.5 points. It’s not often that we’re willing to lay such a big number, but with our Cardinals vs. Chargers predictions for Week 1, we’re going to.

We just said that a ton of LA props look great, and that should lead to a smooth victory for the Chargers. If forced to go with a prop market instead, it has to be Omarion Hampton - Arizona allowed just a tick under 127 rushing yards per game last season. They also ranked in the bottom 10 in terms of passing yards allowed per game.

That’s why Justin Herbert is also set for a huge game and should cash some Cardinals vs. Chargers picks, as Arizona allowed 31 passing TDs last season. We’re going with an overall team approach because the LA defense was on the complete other end of the spectrum; they allowed the fifth-fewest passing yards per game and eighth-fewest rushing yards per game.

To expand on that, they allowed just 16 rushing TDs (third-fewest), so it’s difficult to see Love - who is less than 100% - show out in his NFL debut. Even TEs had the third-most points against Arizona last year, so since everyone can thrive, we have Los Angeles -9.5 (join Splash contests as well) as the best bet from our top Cardinals vs. Chargers predictions for Week 1.

 

 

 

👀 How To Watch Cardinals vs. Chargers NFL Week 1

Given a battle of NFC and AFC West teams, we’d expect it to be in the late afternoon window, and you can see how to watch Cardinals vs. Chargers NFL Week 1 here:

  • Where: SoFi Stadium in Inglewood, CA
  • When: 4:25 PM ET on 9/13
  • Watch on TV: CBS
  • Where to stream: YouTube TV, Fubo, Hulu + Live TV, Paramount+

🔢 Cardinals vs. Chargers Odds, Spreads, Total & Betting Lines

Justin Herbert and LA find themselves as the biggest favorite of the entire NFL Week 1 slate, and we’ve shared the latest Cardinals vs. Chargers odds for Sunday below:

 

 

 

🏉 Cardinals vs. Chargers Injury Report & Latest News

The best news of all for LA is that Joe Alt is healthy, but we know that they’re still not starting with the offensive line intact, given Tyler Biadasz on IR, and even Rashawn Slater is part of the Cardinals vs. Chargers injuries with a questionable tag. We also see Tre’ Harris and Keaton Mitchell with the same designation.

As for Cardinals vs. Chargers news and injuries in Arizona, it’s Jeremiyah Love’s ankle injury that is why we said he is less than 100%. They also have James Conner still recovering, which is why he’s on IR. Along with Will Johnson on defense, there are plenty of Cardinals vs. Chargers injuries that we’ll be keeping tabs on.

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