To close out the 2025 NBA Cup Quarterfinals, all eyes will be on a star-studded affair where the lights always shine brightest. We’ve got LeBron James and the Los Angeles Lakers hosting the Victor Wembanyama-less San Antonio Spurs. We’re here to break down more than just who will be on the court to provide you with the best Spurs vs. Lakers predictions tonight.

To make things even more valuable, not just Spurs vs. Lakers picks, there will be a guaranteed Onyx Odds promo code bonus - legal in over 40 states!

Spurs vs. Lakers Predictions for NBA Cup on Prime, 12/10

Since being the #1 overall pick in the 2023 NBA Draft as the best prospect since LeBron James, Victor Wembanyama’s matchups with the King have been highly sought after. However, they don’t seem to happen more often than not, and even for Spurs vs. Lakers predictions tonight, we have to answer, is Wemby playing tonight?

He wasn’t back in the Spurs' most recent game; he’ll be out tonight, and in that win over the New Orleans Pelicans, it was instead rookie center on the other team, Derik Queen, that had a triple-double. Meanwhile, the Lakers have been off since Sunday, which was a victory over the Philadelphia 76ers. 

Those results mean that these two teams are just one game apart in the standings, but LA was able to see the return of Luka Doncic after missing a couple of games for the birth of his second child. He had a triple-double himself, while LeBron James had 29 points as well. In fact, those two notes are the perfect transition into the best bet from our Spurs vs. Lakers predictions.
 

 

 

Spurs vs. Lakers Best Bet: Los Angeles Team Total Over 118.5 Points (-110 at Onyx Odds)

Again, we already know that Victor Wembanyama is NOT playing tonight, which only boosts our confidence in this pick. Even if he does make his return, which we doubt, we still don’t expect his blocking ability to squander this pick. We can also just look at the recent games for the Spurs to support us.

Sure, they beat the Pelicans (who are 3-22!), but they allowed 132 points in the process! If New Orleans can do that, then our Spurs vs. Lakers predictions speak for themselves. Similarly, if their rookie center can record a triple-double (the first rookie ever to do so with 30+ points), then who knows what Luka Doncic can do.

Furthermore, San Antonio hasn’t allowed fewer than 112 points in six straight games, and in that span, they’ve allowed 136, 125, 130, and 132 points in four of them. LA hasn’t been quite as consistent as that in terms of scoring, but they have scored 133 and 123 in two of their last five games, and two of the others were without Luka Doncic.

With him and LeBron James (not to mention Austin Reaves) taking on a Wemby-less San Antonio squad, we love the best bet from our Spurs vs. Lakers predictions on the Los Angeles team total over 118.5 points (-110 at Onyx Odds).
 

 

 

How To Watch Spurs vs. Lakers Tonight

We’ve said from the start that this is the finale of the 2025 NBA Cup Quarterfinals, and here’s how to watch Spurs vs. Lakers tonight:  

  • Where: Crypto.com Arena in Los Angeles, CA
  • When: 10 PM ET on 12/10
  • Where to stream: Prime Video EXCLUSIVELY
     
 

 

Spurs vs. Lakers Odds, Spreads, Total & Betting Lines

Given the Wemby absence and being at home, we fully expected to see LA favored in the latest Spurs vs. Lakers odds for tonight at Onyx Odds:

 

 

Spurs vs. Lakers Injury Report & Latest News

One of the biggest injuries in the entire NBA, not just Spurs vs. Lakers injuries, is that of Victor Wembanyama, who again has already been ruled out. Also in San Antonio, Jordan McLaughlin is questionable with a hamstring injury.

As for Spurs vs. Lakers injury updates in LA, only Maxi Kleber is listed as questionable with a back injury. As always, keep tabs on more than just those guys with the Fantasy Alarm NBA injury report!
 

 

 

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