MLB PrizePicks Picks Today: Best Pitcher Strikeout Props for Tuesday April 7, 2026

Looking for the best PrizePicks MLB picks today? Our MLB PrizePicks predictions for Tuesday, April 7, 2026, feature two pitcher strikeout props worth targeting on tonight's slate. Cam Schlittler and Jacob Misiorowski both carry dominant early-season form backed by elite stuff, favorable matchup context, and strikeout rates that make the lines on the board look conservative. Here is the full breakdown of where both land and why.

What Are the Best PrizePicks MLB Picks Today?

Tonight's two best PrizePicks MLB pitcher strikeout props feature two of the most electric young arms in baseball in favorable matchups. Both lines carry clear situational edges based on current form, pitch quality, and opponent tendencies. Read below for the full breakdown on each pick.

Cam Schlittler Over 6.5 Strikeouts

Schlittler has been the best starting pitcher in baseball to open the 2026 season, and that is not hyperbole. Through his first two starts against San Francisco and Seattle, the 25-year-old right-hander has thrown 11.2 scoreless innings without issuing a single walk while racking up 15 strikeouts. He struck out eight in his debut against the Giants and seven against the Mariners, making him the first Yankee to begin a season with consecutive starts of at least five scoreless innings and seven strikeouts. His 0.00 ERA and improved cutter, which he added nearly five miles per hour to from 2025 while also improving its shape dramatically, have elevated an already impressive arsenal into something genuinely special.

Tonight, he makes his home debut at Yankee Stadium against the Athletics, the most strikeout-prone lineup in baseball against right-handed pitching to open the year. Oakland is punching out at a nearly 30 percent clip against right-handers, the highest rate in baseball, and that number creates a near-ideal environment for a pitcher like Schlittler, whose combination of a 98-plus four-seamer, improved cutter, and sharp secondary stuff generates whiffs at every level of the zone. Seven strikeouts in a home start at Yankee Stadium against the team striking out at the highest rate in the sport is not an ambitious ask for a pitcher on this kind of run. Back the over.

Jacob Misiorowski Over 6.5 Strikeouts

Misiorowski turned his Opening Day start into one of the most dominant pitching performances of the early 2026 season. The 23-year-old set a Brewers franchise record with 11 strikeouts in five innings against the White Sox on March 26, touching 101.1 mph and generating 19 whiffs on his four-seamer alone. In his second start, he added seven more strikeouts, giving him 18 across 11 innings with a 2.45 ERA and a strikeout rate that carried into 2026 at 33 percent. His slider averages 94.3 mph, a number that does not belong on a breaking ball for any pitcher at any level, and his fastball-slider combination generates elite swing-and-miss from both sides of the plate.

Tonight he faces the Red Sox at Fenway Park in what is being billed as one of the marquee pitching matchups of the evening, with Garrett Crochet on the other side. Boston ranks third in baseball in strikeout rate against right-handed pitching to open the season at 29 percent, making them one of the most favorable opponents a power righty could draw. Facing a lineup that is already whiffing at this rate removes nearly every obstacle to a big strikeout night. Seven punchouts against a lineup punching out at a 29 percent clip against righties is well within reach for a pitcher who has already posted 11 in a single outing this month. Give me the over.

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