Week 4 of the NFL season is upon us and here is a look at some key AFC players for the weekend.Champ Bailey had two interceptions the last time he faced off with his nemesis, the Raiders.Reggie Bush is injured (knee) but over his past seven games he is averaging a whopping 111 rushing yards per contest. The only time he faced the Cardinals in his career was the playoffs in 2010 when he was a member of the Saints. He produced 108 yards from scrimmage in that game (84 rushing).Jamaal Charles ran for 233 yards last week, the second games of his career of 230 yards rushing (only all-time great Jim Brown has more with three such outings). Charles faces a Chargers club that he has beaten for an average of 5.9 yards a career through 46 attempts.Andy Dalton has killed it the past two weeks throwing for 646 yards and two scores. He faces a Jaguars team that has allowed 258 yards passing a game this season though they have permitted just two passing scores in three games. The past six September games that Ryan Fitzpatrick has started have resulted in 17 touchdown passes. In five career matchups he's thrown for seven scores but an abysmal 12 interceptions.Joe Flacco has led the Ravens to a 12-0 record at home in their last 12 contests, and for his career he's 8-0 against the Browns with a 94.4 QB Rating. Unfortunately his success has been mighty limited against the Patriots has he has thrown for seven scores and 12 interception in five career matchups with the Pats.Arian Foster has run for 143 and 115 yards the last two times he has faced the Titans. Ben Tate hasn't fared to poorly either as he has run for 201 yards, at an average clip of 6.5 yards a carry, in two contest.A.J. Green caught five balls for 90 yards an a score his his contests versus the Jaguars last year.Jermaine Gresham started out the year slowly catching seven balls for 67 yards the first two weeks of the season. Last week he woke up against the Redskins catching five balls for 64 yards an a score. This week he takes on a Jaguars club that has been pretty solid against the tight end allowing the 12th fewest points to the position and no scores this season. When Shonn Greene runs for 100-yards, the Jets never lose (they are 4-0). Too bad he is a near lock not to get there against a Niners defense that is allowing 91 yards a game on the ground.Rob Gronkowski had a terrible statistical outing in Week 3 with two receptions for 21 yards as he was asked to block against the Ravens. Don't look for him to be held down again. After all, Gronk has 100 yards and two touchdowns in each of his last two contests against the Bills. He also has seven scores in four games against the Bills.Andre Johnson has scored nine times against the Titans, his highest total against any opponent. He's also caught 87 balls for 1,144 yards in 16 career matchups.Chris Johnson has appeared in eight games against the Texans in his career averaging 87.6 yards a contest. This season the Texans are allowing a mere 67.7 yards per game on the ground while Johnson has run for 45 yards on 33 carries for the season. Ghastly.Stevie Johnson has scored a touchdown in each of his last four games. He's also scored three times in his last four contests versus the Patriots.Santonio Holmes went for a career best nine receptions last week as he also gained 147 yards. For his career he's caught 80 balls for 1,399 yards against NFC clubs in 20 contests.Justin Houston of the Chiefs had three sacks last week given him a total of 9.5 sacks in his last eight forays onto the gridiron.  Maurice Jones-Drew hasn't exactly killed it in his career against the Bengals with a total of just 118 yards on 29 rushing attempts in two previous matchups. He's still scored two times though so there is obviously no need to worry.Ryan Mathews has found the end zone three times in his last three games against the Chiefs. Teammate Antonio Gates has scored 12 times in his career against the team from Kansas City, his highest total against any opponent in his prolific career.Darren McFadden has run for 637 yards against the Broncos, his largest total against any team. He's also run for at least 119 yards in the last three meetings with two of the outings going for 150 and 165 yards.Willis McGahee ran all over the Raiders the last time he faced them going for 163 yards and two touchdowns. For his career he has six rushing scores in four matchups with the Silver and Black. Hopefully he will be able to see close to a full workload this week even with his sore ribs.Dennis Pitta has 30 targets on the year, one behind Jimmy Graham for the most in football for a tight end. The Browns have been pretty tough this year against tight ends as the 10th most stingy defense against the position.Trent Richardson is one of three players in the NFL that has two rushing scores and one receiving (the others are Arian Foster and C.J. Spiller). Richardson has a tough matchup though this week against a Ravens club that has surprisingly allowed four scores to the running back position this year.Ray Rice dominates everyone, and the Browns are no exception to that rule. In his last five battles with the club from Cleveland he's averaged 110.4 yards rushing per contest.Matt Schaub is coming off a 290 yard, four score game and this week he gets to face the worst AFC defense in terms of fantasy points allowed to the quarterback in the Tennessee Titans. The Titans have allowed a whopping eight TD passes in three games. Last week the Titans were the first team in NFL history to have five touchdowns travel at least 60 yards. Not one of them came from former game breaker Chris Johnson. The score were by Tommie Campbell, Harek Cook, Darius Reynaud, Nate Washington and Alterraun Verner.J.J. Watt has recorded at least 1.5 sacks in each of his three games for the Texans this season. Linemate Antonio Smith recorded two sacks the last time the Titans faced the Texans.Eric Weddle has picked off three passes the last two times he's gone up against the Chiefs. Matt Cassel better be on his best behavior. The last time that Wes Welker faced the Bills he had the best game of his career with 16 receptions, 217 yards and two touchdown.Danny Woodhead had double the snap count than Steven Ridley in Week 3. Will that continue in Week 4 since Woodhead has averaged seven yards per carry in his 23 attempts against the Bills in his career?  Ray Flowers can be heard daily on Sirius/XM Radio on The Fantasy Drive on Sirius 210 and XM 87, Monday through Thursday at 7 PM EDT and Friday's at 9 PM EDT. Ray's analysis can be found at BaseballGuys.com and his minute to minute musings can be located at the BaseballGuys' Twitter account.