MLB Best Bets Today, 9/5: Picks, Predictions & Player Props - Wednesday
Welcome to tonight’s MLB best bets for this slate of MLB action here at Fantasy Alarm on this Friday, September 7th, 2025! Welcome to the weekend, everyone. I hope you all got along just fine. Our reward to end the week is a full slate of baseball to keep an eye on, even if you are planning to watch some NFL Friday night action too! Below are my favorite bets for tonight’s action. Good luck, and let’s take home some green.Â
In this MLB Best Bets Today article, you will find a wide array of choices from some Money Lines to game totals and, on occasion, some player props! Check out the rationale, and if you agree with me, make sure to tail and good luck!
Now, let's dive into my expert MLB Best Bets today!
- Season Record: 260-180-10
- Bankroll: +41.1 units
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MLB Picks, Predictions & Best Bets Today, 9/5
Dodgers vs. Orioles Predictions
The Dodgers remain on the eastern side of the country this weekend and will try to pick themselves up after a sweep at the hands of the Pirates as they start a new series with the Orioles. There are a couple of different wagers I love in this game, so let’s dive into the matchup.Â
Tyler Glasnow will start for the Dodgers on the bump, and he had a great August, as through 5 starts he held down a 3.45 ERA and allowed just 19 hits on 28.2 innings pitched. He also racked up 32 strikeouts during that time, and that’s where the first wager comes in. The Orioles' lineup over the past month of games has a K-rate of 24.6% the 3rd highest mark in MLB, and it doesn’t appear that’s going to end anytime soon, with a team wOBA of .315, which is bottom half of the league. With Glasnow throwing heat, he should mow down the Birds’ batters tonight so I like him to go over his 6.5 strikeout prop tonight.Â
In addition to backing Glasnow, I like the spot for the Dodgers bats tonight, too, as Dean Kremer continues to be painful to watch. He has a 5.59 ERA in the past month and has surrendered 32 hits in the last 29 innings pitched. He’s weaker against lefties too allowing a .288 average in the month of August against them. That’s enough to go on to bet Shohei Ohtani to get going tonight as he’s hitting .304 with a .950 OPS over the past week. I like him to go over his hits/runs/RBIs tonight, hitting leadoff for this offense.Â
- Pick: Tyler Glasnow (LAD) Over 6.5 Strikeouts (-150 on DraftKings)
- Pick: Shohei Ohtani (LAD) Over 2.5 Hits/Runs/RBIs (-120 on DraftKings)
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Padres vs. Rockies Predictions
How does a team that is struggling offensively snap out of a slump? With a trip to Coors Field to take on the Rockies! The numbers for the Padres have been low recently with ISO and BABIP, but I like their spot tonight against Kyle Freeland!
Freeland has a 5.33 ERA over the past 6 starts and has allowed 35 hits on 27 innings pitched during that span. The Padres ought to make this matchup their own, given how most of the lineup hits against left-handed pitching and the fact that at home, the Rockies' southpaws allow a batting average of .355!Â
The Padres also have Nick Pivetta pitching for them tonight, and he’s been nails with a 2.95 ERA over his last 6 starts that have spanned 36.2 innings! Due to this, I will be taking the Padres on the Run Line as they continue to push the Dodgers in the National League West for the division crown!Â
- Pick: Padres Run Line -1.5 (-140 on DraftKings)
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Best MLB Prop Bets & Other Picks Today, 9/5
- Pick: Chris Sale (ATL) Over 7.5 Strikeouts (-140 on DraftKings)
- Pick: Guardians Money Line (+125 on DraftKings)
- Pick: Mets & Reds Over 9 Runs (-120 on DraftKings)
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