MLB Home Run Picks Today: Best Home Run Predictions for May 13th, 2026
Wednesday's full slate gives us plenty to work with for our best MLB home run picks and predictions for May 13th. There's no shortage of favorable matchups to dig into, and we've broken it all down from ballpark factors to pitcher vulnerabilities and everything in between to bring you our top MLB home run predictions for today.
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⚾ Top MLB Home Run Picks for Today
We never have a shortage of content to pair with our MLB home run picks, so make sure you're also checking out our MLB expert picks for more standard markets and game lines. As for our top MLB home run predictions for Wednesday, here are the three names we're breaking down:
🔥 Best Matchups for Home Runs Today, 5/13: Ballpark Factors & Weather Impact
As always, our MLB weather report is a must-check before locking in any MLB home run picks Wednesday - wind and conditions can make or break a longball. Beyond the weather, we're factoring in ballpark dimensions, pitcher HR/FB rates, handedness splits, and barrel data to make sure we're putting our best foot forward with every MLB home run prediction below.
JJ Bleday (+393)
Look, we put a ton of emphasis on Nationals vs. Reds last night, and while our guys didn’t cash, one of the ones in our best MLB home run parlay did, and there were still plenty of dingers in that game. That’s just another reason for checking out our breakdowns and not just the names! So, let’s get further into the first of our best MLB home run picks for today.
We’re going to stick with the home team and a guy who cashed a hits+runs+RBI pick for us last night. JJ Bleday is a lefty that gets to face Jake Irvin’s great HR/fly ball ratio (for hitters that is) and had his best at-bat in the bottom of the 9th inning last night. Washington’s bullpen remains awful, so we’ve got JJ Bleday to hit a HR (+393 at Novig) as the first of our MLB home run picks today.
Shea Langeliers (+290)
Let’s transition right to another location that we love to target - the home of the Sacramento River Cats. While it feels like we’re going back to the well again, it’s not for a lack of reasons. St. Louis starter Matthew Liberatore is great for MLB home run picks across the board, from average exit velocity to whiff percentage and everything in between.
That’s why we’re focused on the A’s lineup rather than the Cards. Specifically, we’re going with the “square” pick on their catcher with Liberatore being a lefty. Shea has been smashing southpaws this season to the tune of a .366 average and 1.054 OPS. That’s great news for us, hence why we’re adding to our best MLB home run picks for today with Shea Langeliers to hit a HR (+290 at BetMGM).
Oneil Cruz (+438)
A location that may surprise you is PNC Park, as it’s not as famous for homers as the home of the Pittsburgh Pirates opponents today, which would be the Colorado Rockies. Although we’re not at Coors Field, we do have Jose Quintana on the mound. He’s a lefty with a terrible strikeout rate, so why not pick on him with our best MLB home run picks for today?
To do so, we’re locking in Pittsburgh’s elite hitter versus lefties this season. That would be Oneil Cruz, and while we can discuss his defense at a later time, the fact remains that he’s hitting .327 against lefties this year, along with a .965 OPS. With yet another great matchup, we’re adding to our best MLB home run picks for today with Oneil Cruz to hit a HR (+439 at Novig).
🚀 Longshot Home Run Picks Today
We always go above and beyond with our MLB home run picks, and that means finding you some extra value beyond our top three targets. Check out the juicier odds below for Wednesday's longshot play:
We’re heading to Minnesota for Marlins vs. Twins with this one. Simeon Woods Richardson is on the mound for the home team, so who says no? This switch-hitter and leadoff man has four dingers, so let’s get one from the first pitch to cash our best MLB home run longshot pick for today!
💲 Today’s Best MLB Home Run Parlay
There's always more value to squeeze out of our MLB home run predictions, so here's how to combine them into Wednesday's best parlay:
Between our top three MLB home run picks and the longshot play, you've got a full set of names to root for across Wednesday's slate. Take advantage of our MLB home run predictions for May 13th, however you see fit!
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