The 2026 college football season rolls on! Saturday’s matchup between the Indiana Hoosiers and Michigan Wolverines headlines CFB Week 8. That means it’s time to dive into #6 Indiana vs. Michigan predictions before kickoff. We’ll preview the game, break down the matchup, and dish out expert #6 Indiana vs. Michigan picks. Plus, get to know the latest #6 Indiana vs. Michigan odds ahead of Saturday’s showdown.
#6 Indiana vs. Michigan Predictions for CFB Week 8, Saturday 10/24
Before we get to our #6 Indiana vs. Michigan predictions, let’s set the stage for Saturday’s game. Indiana enters as 6.5-point road favorites with a 42.5 over/under on BetMGM Sportsbook. The Hoosiers are 6-1 heading into this matchup, while the Wolverines are 4-2.
Without further ado, let’s dive into our #6 Indiana vs. Michigan picks. There’s a certain betting angle worth locking in before Saturday’s matchup kicks off. Good luck!
#6 Indiana vs. Michigan Expert Pick: Indiana -6.5 (-135 on BetMGM Sportsbook)
Indiana will hope to bounce back after losing a close one to Ohio State last week. The Hoosiers are the team to back for our #6 Indiana vs. Michigan predictions. Let’s break down the matchup and the betting angle.
A letdown for Indiana after the Ohio State loss is definitely possible. Or, the Hoosiers will be more motivated to get back on track and earn a convincing road win over a quality opponent. Their playoff hopes are still very much alive in this expanded field era. Count on head coach Curt Cignetti to have his group ready for the rebound.
Indiana’s top-tier defense can hold Michigan in check. The Hoosiers rank 18th nationally in adjusted defensive EPA/Play and 17th in defensive success rate. They’re especially strong against the run, which spells trouble for the Wolverines.
Michigan has gotten underwhelming quarterback play from Bryce Underwood. So much so that backup Tommy Carr relieved him last week. Carr, though, also doesn’t offer much in the passing attack. The Wolverines prefer to lean on the run, which will be a problem against Indiana’s stalwart rush defense.
Meanwhile, Michigan’s own defense grades out well. However, the Wolverines also haven’t faced a quality offense yet this year. Matchups against Oklahoma, Iowa, Minnesota, and Penn State have all featured subpar offenses. Indiana will be a wake-up call for Michigan, as the Hoosiers can generate explosive plays both through the air and on the ground.
So, Indiana is the play. The Hoosiers are much more battle-tested and proven. They nearly beat Ohio State last week, if only wideout Nick Marsh landed inbounds on the last-second near-touchdown. Cignetti will have his team ready to win by at least a touchdown on the road here.
How To Watch #6 Indiana vs. Michigan CFB Week 8
- Date: Saturday, October 24, 2026
- Time: 12:00 PM ET
- Location: Michigan Stadium, Ann Arbor, Michigan
- TV: FOX
#6 Indiana vs. Michigan Odds, Spread, Total & Betting Lines
After #6 Indiana vs. Michigan predictions, let’s take a look at the betting lines for this college football matchup. Here are the latest #6 Indiana vs. Michigan odds from BetMGM Sportsbook ahead of Saturday’s showdown.
- Spread: Indiana -6.5 (-135) | Michigan +6.5 (+105)
- Moneyline: Indiana -295 | Michigan +240
- Over/Under: 42.5 (Over -110 | Under -108)
#6 Indiana vs. Michigan Injury Report & Latest News
Indiana Hoosiers:
- None
Michigan Wolverines:
- WR Kendrick Bell – Out
- TE Mason Bonner – Out
- WR Braydon Alford – Out
- RB Micah Ka’apana – Out
- DE Julius Holly – Out
- OL Ace Hamilton – Out
- OL Andrew Sprague – Out
- S Rod Moore – Questionable
- DE Dom Nichols – Questionable
- LB Aisea Moa – Questionable
- DT Enow Etta – Questionable
- OL Jake Guarnera – Questionable
- OL Brady Norton – Questionable
- OL Blake Frazier – Questionable
- OL Andrew Babalola – Probable
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