Arizona Diamondbacks

Dennis Santana

#59 Active
RP Arizona Diamondbacks 6'2" · 202 lbs Bats: R · Throws: R
Season SV
3
Season ERA
6.05
Season WHIP
1.01
Season K
48
Season HLD
5
Next Matchup @ COL Tue 3:10 PM ET · SP: Y. Flande

2026 Fantasy Baseball Player Profile

Dennis Santana’s 2025 season was a masterclass in efficiency that saw him rise from a mid-2024 waiver claim to the anchor of the Pirates' bullpen. After stabilizing his command, Santana blossomed into one of the most reliable relievers in the National League, posting a career-best 2.18 ERA and a stifling 0.87 WHIP over 70.1 innings. While he lacks the triple-digit velocity of some of his contemporaries, his 96th-percentile chase rate—fueled by a devastating slider that he threw 46% of the time—made him nearly unhittable. When the Pirates moved David Bednar to the Yankees at the 2025 trade deadline, Santana stepped seamlessly into the ninth inning, converting 11 of his final 13 save opportunities.

Entering 2026, Santana is the presumptive Opening Day closer, though he is operating in a much more crowded high-leverage mix. In January, he avoided arbitration by signing a one-year, $3.5 million contract, securing his spot as the veteran leader of the relief corps. So far in spring training, manager Don Kelly has been non-committal about a fixed role, opting to pair Santana with newly acquired left-hander Gregory Soto in a "righty-lefty punch" for the late innings. Santana made his spring debut on February 23 against the Yankees, throwing a scoreless frame and showing the same "filthy" slider-sinker combo that defined his breakout.

For fantasy managers, Santana is a polarizing save source with an ADP around 166.

DFS Last 5

Game Log

2026 Regular Season
DATE OPPONENT DEC IP H R ER HR BB SO ERA WHIP PC RESULT
Sep 16 vs. Miami Marlins 2.0 0 0 0 0 0 0 4.64 1.30 16 L 4-3
Sep 13 vs. Texas Rangers 1.0 0 0 0 0 0 0 4.83 1.35 9 L 7-6
Sep 11 vs. Texas Rangers 2.0 2 0 0 0 1 2 4.93 1.38 25 W 1-9
Sep 8 @ Kansas City Royals 1.0 1 0 0 0 0 3 5.13 1.37 16 W 5-3
Sep 7 @ Kansas City Royals SV 0.2 0 0 0 0 0 1 5.24 1.38 11 W 5-4
Aug 29 @ San Francisco Giants 0.1 2 0 0 0 0 0 5.32 1.40 9 L 2-7
Aug 28 @ San Francisco Giants 1.0 0 1 0 0 1 1 5.36 1.37 24 W 10-6
Aug 25 vs. Chicago Cubs 1.1 0 0 0 0 0 1 5.48 1.38 19 W 4-5
Aug 22 vs. Cincinnati Reds 1.0 2 1 1 1 0 1 5.65 1.42 13 L 11-5
Aug 21 vs. Cincinnati Reds 1.1 0 0 0 0 0 2 5.57 1.40 20 W 0-9
Aug 17 @ Boston Red Sox 0.1 0 0 0 0 0 0 5.75 1.45 3 L 1-11
Jul 11 vs. Milwaukee Brewers HLD 1.0 0 0 0 0 0 1 5.80 1.46 19 W 2-3
Jul 9 vs. Atlanta Braves 1.0 3 4 4 1 2 1 5.95 1.50 25 L 10-5
Jul 8 vs. Atlanta Braves L 1.0 2 2 2 1 0 2 5.17 1.41 16 L 3-0
Jul 5 @ Washington Nationals 1.0 1 0 0 0 0 0 4.82 1.39 16 W 11-5
Jul 4 @ Washington Nationals 1.0 0 0 0 0 0 1 4.95 1.40 11 W 7-1
Jul 1 @ Philadelphia Phillies 1.0 2 2 2 1 0 2 5.09 1.44 15 L 6-10
Jun 28 vs. Cincinnati Reds 1.0 0 0 0 0 2 1 4.72 1.43 23 W 4-9
Jun 26 vs. Cincinnati Reds 1.1 0 0 0 0 0 2 4.86 1.41 14 L 6-4
Jun 23 vs. Seattle Mariners 1.0 0 0 0 0 1 1 5.06 1.47 18 L 3-2
Jun 21 @ Colorado Rockies 1.0 3 3 3 1 0 0 5.23 1.48 18 W 8-6
Jun 17 @ Las Vegas Athletics 1.0 0 0 0 0 0 2 4.50 1.43 11 W 12-4
Jun 15 @ Las Vegas Athletics 1.0 0 0 0 0 0 2 4.66 1.48 10 L 2-11
Jun 11 vs. Los Angeles Dodgers 1.0 0 0 0 0 0 0 4.82 1.54 16 L 8-6
Jun 9 vs. Los Angeles Dodgers 1.1 1 0 0 0 2 1 5.00 1.59 31 L 12-3
Jun 5 @ Atlanta Braves 1.0 0 0 0 0 0 1 5.26 1.56 7 L 3-6
Jun 2 @ Houston Astros 0.1 3 2 2 0 1 1 5.47 1.62 19 W 10-6
May 30 vs. Minnesota Twins HLD 0.2 0 0 0 0 0 2 4.81 1.48 7 W 9-10
May 27 vs. Chicago Cubs 1.1 0 0 0 0 2 1 4.94 1.52 22 L 10-4
May 26 vs. Chicago Cubs 1.0 1 0 0 0 1 1 5.24 1.52 18 W 1-12
May 22 @ Toronto Blue Jays 1.0 3 3 3 0 1 2 5.48 1.50 31 L 2-6
May 20 @ St. Louis Cardinals 1.0 0 0 0 0 0 1 4.43 1.38 11 W 7-0
May 17 vs. Philadelphia Phillies 1.0 1 1 1 1 0 2 4.66 1.45 12 L 6-0
May 15 vs. Philadelphia Phillies L 0.0 4 3 2 0 0 0 4.42 1.47 18 L 11-9
May 14 vs. Colorado Rockies 1.0 0 0 0 0 0 0 3.44 1.25 12 W 2-7
May 10 @ San Francisco Giants 0.2 2 0 0 0 0 0 3.63 1.33 19 L 6-7
May 7 @ Arizona Diamondbacks HLD 1.0 0 0 0 0 1 0 3.78 1.26 13 W 4-2
May 5 @ Arizona Diamondbacks 1.0 3 2 2 0 0 0 4.02 1.28 15 L 0-9
Apr 29 vs. St. Louis Cardinals 1.0 0 0 0 0 0 0 3.07 1.16 9 L 5-4
Apr 27 vs. St. Louis Cardinals L 0.2 4 4 4 2 2 0 3.29 1.24 27 L 4-2
Apr 25 @ Milwaukee Brewers 1.0 1 0 0 0 1 1 0.69 0.85 17 W 6-3
Apr 22 @ Texas Rangers 1.0 0 0 0 0 0 2 0.75 0.75 9 W 8-4
Apr 17 vs. Tampa Bay Rays 1.0 1 0 0 0 1 1 0.82 0.82 17 W 1-5
Apr 16 vs. Washington Nationals L 1.0 1 1 0 0 0 0 0.90 0.70 11 L 8-7
Apr 15 vs. Washington Nationals SV 1.0 0 0 0 0 0 0 1.00 0.67 21 W 0-2
Apr 11 @ Chicago Cubs BS 1.0 1 1 1 0 2 0 1.13 0.75 27 W 4-3
Apr 10 @ Chicago Cubs SV 1.0 0 0 0 0 0 2 0.00 0.43 13 W 2-0
Apr 4 vs. Baltimore Orioles W 1.0 0 0 0 0 0 1 0.00 0.50 13 W 2-3
Apr 3 vs. Baltimore Orioles HLD 1.0 0 0 0 0 0 1 0.00 0.60 10 W 4-5
Mar 31 @ Cincinnati Reds HLD 1.0 1 0 0 0 0 0 0.00 0.75 17 W 8-3
Mar 29 @ New York Mets W 1.0 0 0 0 0 0 1 0.00 0.67 13 W 4-3
Mar 28 @ New York Mets 1.0 0 0 0 0 1 0 0.00 1.00 18 L 2-4
Mar 26 @ New York Mets 1.0 0 0 0 0 1 1 0.00 1.00 18 L 7-11
Total2-452.1453027823484.641.30852

AVG, OBP, SLG, ERA and WHIP are season-to-date through each game, not that game alone — so the column reads as a trend and its last value is the season figure. They stay season-to-date when the log is filtered by opponent; the figure for the filtered games is the one in the Total row. The second game of a doubleheader is marked (2).

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