Welcome to Fantasy Alarm's MLB DFS picks and daily fantasy playbook for Tuesday, October 6th. Our MLB DFS projections combine advanced pitching metrics, platoon splits, strikeout prop data, and ownership positioning to identify the sharpest plays on every slate. Whether you are targeting DFS Projections, running lineups through our DFS Optimizer, tracking ownership trends, or checking confirmed lineups, Fantasy Alarm has the tools to sharpen your edge. 

This MLB DFS playbook covers every key position on DraftKings and FanDuel with our best MLB DFS picks for today.

Slate: 2-Game Main | Lock Time: 6:00 pm ET, Tuesday, October 6th, 2026

Vegas Totals: MIL/SD (highest-projected game total) & LAD/ATL (second-highest projected game total)

Highest K-Projections: Chris Sale 7.5 O/U (+111), Yoshinobu Yamamoto 6.5 O/U (+117), Nick Pivetta 3.5 O/U (-158)

MLB Weather Today, 10/6

No weather concerns today.

Top Options For Strikeouts

K-prop lines and value ratings are incorporated below for DFS and prop context. These are the arms building the highest strikeout ceilings on the 10-game slate.

Our model identifies these arms as the highest-ceiling plays for Alt-K lines today:

Chris Sale: 30.9% K% (11.1 K/9)

Nick Pivetta: 30% K% (10.9 K/9)

Yoshinobu Yamamoto: 25.7% K% (8.9 K/9)

Dustin May: 23.2% K% (8.9 K/9)

Best Odds For A Win

The following MLB DFS picks offer a combination of favorable win odds, sustainable ERA and xFIP metrics, and soft opponent matchups. Each carries K-prop lines worth noting alongside their DFS value at reduced ownership relative to the top tier.

Los Angeles Dodgers Breakdown

When in need, call Yoshi. Yoshinobu Yamamoto heads to the mound for the Dodgers in Game 3 with the series tied 1-1. Yamamoto has a matchup against a Braves offense who posted a 98 wRC+ in the second half of the year. Atlanta struck out 22.3% of the time against righties over that span too. Yamamoto has some of the best odds on the slate of any of the four pitchers, arguably the best.

It's hard to love anything Dodgers related on the offensive side of the baseball with Chris Sale on the mound, but here are the Dodgers that are good against lefties this year;

Atlanta Braves Breakdown

The Braves took a risk not pitching Chris Sale in Game 2 and it worked and now, heading back to Atlanta, the Braves send Sale to the mound in a series tied at one. Sale faced the Dodgers twice this year with the latest meeting being a complete game shut out. He put up 22+ DKP in each outing. The Dodgers had the 6th-highest wRC+ in the second half vs. LHP while striking out at just 20% of the time.

Truly the only thing you can ding Yamamoto for is that he allowed 20 home runs this season. Now, that's across 28 starts, so it's not that many based on how many outings he had, but he can be susceptible to a bomb here and there. It's slightly better for right-handed bats because their flyball rate and home runs are slightly higher than lefties. That means Ronald Acuna is at the forefront of our minds. It's possible Austin Riley too.

Of course, if you're looking to be different, Michael Harris, Matt Olson, and Drake Baldwin all have massive upside from the left side.

Milwaukee Brewers Breakdown

Dustin May is making his first postseason start this year but I'm not sure how long he is for the game. He hasn't thrown more than 70 pitches since September 11th and hasn't topped three innings over that span. Obviously, down the stretch, the Brewers wanted to keep him healthy, but I'm unsure his limited workload will make him more likely to work deeply into this game. He's probably the fourth best option of the starters today.

If you look towards the Brewers offense today, things are interesting because Nick Pivetta has been quite lucky if you're looking under-the-hood. Over the last 30 days, lefties only have a .023 ISO but .207 xISO while righties have posted a .250 ISO and .227 xISO while posting a .434 wOBA and .416 xwOBA.

Here are the Brewers bats we're looking at;

San Diego Padres Breakdown

The numbers look really good for Nick Pivetta on the surface but they don't look the same under the hoof. He was pulled after 66 pitches in his first postseason start and with the Padres facing elimination, the hook could be really, really short. I worry about him against the third-rated offense against right-handed pitching since the All-Star break. They do, however, strike out 24.3% of the time vs. RHP. So that right there is the appeal for Pivetta because he has a 30% K-rate on the season.

The Padres offense could be the highest scoring unit of the day as they take on Dustin May. May, over the last 90 days (which was 1,000 pitch sample), has really not pitched well. Righties have hit him hard over that span (.180 ISO, .191 xISO, .355 wOBA, .354 xwOBA) and lefties have good expected numbers (.153 xISO, .353 xwOBA). 

All of that data leads me to Fernando Tatis, Manny Machado, and Ty France are priorities. Xander Bogaerts to a lesser degree too, but the righties are priority. I definitely like rounding out my stacks with Jackson Merrill and Dustin Harris – if he's hitting second.