Welcome to Fantasy Alarm's MLB DFS picks and daily fantasy playbook for Monday, June 22nd. Our MLB DFS projections combine advanced pitching metrics, platoon splits, strikeout prop data, and ownership positioning to identify the sharpest plays on every slate. Whether you are targeting DFS projections, running lineups through our DFS optimizer, tracking ownership trends, or checking confirmed lineups, Fantasy Alarm has the tools to sharpen your edge. 

Today's 9-game main slate has multiple different directions to go considering we have games in Coors Field and Great American Ball Park, plus multiple stud pitchers on the mound. This MLB DFS playbook covers every key position on DraftKings and FanDuel with our best MLB DFS picks for today.

Slate: 9-Game Main  |  Lock Time: 7:07 PM ET, Monday, June 22nd, 2026

Vegas Totals: BOS/COL (highest-projected game), MIL/CIN - LAD/MIN (tied for second-highest game), BAL/LAA (third-highest game)

Highest K-Projections: Dylan Cease 6.5 O/U (-138), Kyle Bradish 6.5 O/U (+110), Gavin Williams 5.5 O/U (-155), Hunter Brown 5.5 O/U (-113), Shota Imanaga 5.5 O/U (+115) 

MLB Weather Today, 6/22

CHC @ NYM - High chance of a delay with risk of postponement or suspended game very much in the range of outcomes.  

MIL @ CIN -  Low chance of a late start, but the game should play fine regardless. 

MLB DFS Lineup Picks: Starting Pitchers

MLB DFS Top Pitchers

Hunter Brown (HOU)

Analysis: Brown had a successful return to action last week after missing nearly three months with a shoulder strain. He used 92 pitches to record seven strikeouts in 5.2 innings of one-run ball against the Tigers in his first start off the IL. Tonight, he draws a tough matchup against an average Blue Jays offense that owns the lowest strikeout rate in baseball against righties. 

Dylan Cease (TOR)

Analysis: Cease has been one of baseball's top strikeout arms, with a 36.3% strkeout rate that ranks second in the league among pitchers with at least 50 innings pitched. An above-average 45.6% groundball rate and miniscule 5% barrel rate have helped him post a sterling 2.71 ERA through 13 starts. Tonight's matchup against the Astros grades out as neutral, as they own a 103 wRC+ and rank 13th in strikeouts when facing right-handed pitching. 

Gavin Williams (CLE)

Analysis: Williams has posted the highest strikeout, walk, and groundball rates of his career. He is allowing too much hard contact, which has led to some inconsistency, but he has as much upside as anyone on the slate. The White Sox are an average offense against righties (99 wRC+), and they have struck out at the third-highest rate in baseball. They also are projected to roll out seven lefties in their lineup (including switch-hitters), and Williams has struck out lefties at a higher clip than righties in his career.   

MLB DFS Value Pitchers

Kyle Bradish (BAL)

Analysis: Bradish is coming off a season-best 12 strikeouts against Seattle in his last start. He has dealt with some inconsistency this season, fueled by an 11.7% walk rate and 10.3% barrel rate, but he draws a high-upside matchup against an Angels team that has struck out at the highest rate in baseball.  

Shota Imanaga (CHC)

Analysis: Monitor the weather in this game, as there is a strong chance of a delay at some point. Tune into the live stream at 5:00 pm ET for updates on whether Imanaga remains in play. He draws a plus matchup against a Mets team that owns a below-average 92 wRC+ against lefties. Imanaga has flashed double-digit strikeout upside when his splitter is working and he's locating well. He has a massive home run problem when that is not the case.  

Grant Holmes (ATL)

Analysis: Holmes has been inconsistent this season, as he's experienced a decline in strikeout rate and an increase in hard-hit rate. The dip in strikeouts looks to be mostly fake, as his 12.6% swinging-strike rate is in line with last season's 13.0% rate when he posted a 25% strikeout rate. He has been especially unlucky with strikeouts to righties, where he's posted a 14.3% swinging-strike rate but only an 18.5% strikeout rate. Holmes has also struggled with lefty power this season, and the Padres only project to have three lefties in the lineup. 

Top Options For Strikeouts

K-prop lines and value ratings are incorporated below for DFS and prop context. These are the arms building the highest strikeout ceilings on the 9-game slate.

Our model identifies these arms as the highest-ceiling plays for Alt-K lines today:

Hunter Brown: 37.5% K% (13.2 K/9)

Dylan Cease: 36.3% K% (13.6 K/9)

Gavin Williams: 27.9% K% (10.1 K/9)

Kyle Bradish: 24.2% K% (9.4 K/9)

Shota Imanaga: 24.1% K% (8.7 K/9)

Best Odds For A Win

The following MLB DFS picks offer a combination of favorable win odds, sustainable ERA and xFIP metrics, and soft opponent matchups. Each carries K-prop lines worth noting alongside their DFS value at reduced ownership relative to the top tier.

MLB DFS Lineup Picks: Stacks & Hitters

MLB DFS Top Hitters

Coors Field Red Sox  

Willson Contreras (1B, BOS), Jarren Duran (OF, BOS) & Wilyer Abreu (OF, BOS) 

Analysis: Contreras has easily been Boston's best hitter and is having the best season of his career. He has posted a .227 ISO against righties this year. Duran has been abysmal in June and overall this season, but he posted a .211 ISO against righties last season. Abreu has been more consistent, but he's also struggling in June with a 91 wRC+. The matchup is the difference maker as they square off against Feltner in Coors Field. The righty has been lit up for a 5.05 ERA while allowing a 10.6% barrel rate, 44.7% hard-hit rate, and 1.5 HR/9. 

Great American Brewers 

Jackson Chourio (OF), Brice Turang (2B), Christian Yelich (OF), Jake Bauers (1B/OF)

Analysis: The Brewers' top bats make for elite options given their prime matchup with Singer in one of baseball's best home run parks. Chourio, Turang, and Bauers all own an ISO of at least .247 against righties this season. Yelich is having a down season, but he posted a .230 ISO against righties just last year. Singer has allowed a 10.7% barrel rate and 2.3 HR/9 while striking out just 17.1% of batters. 

Pete Alonso (1B, BAL), Gunnar Henderson (SS, BAL), & Taylor Ward (OF, BAL)

Analysis: Alonso has been better against righties the last two seasons, but he owns a .258 ISO against lefties in his career. Henderson is all the way up at a .259 ISO against lefties this season, and Aldegheri has shown reverse splits in his very limited career. Ward is experiencing a power outage this season, but he's getting on base at the highest rate of his career. Maybe a trip out west against the team that drafted him and traded him away will spark something.  

MLB DFS Value Hitters

Mickey Gasper (C, BOS) & Caleb Durbin (3B, BOS)

Analysis: Value options hitting in the lineup of the team with the high implied run total on the slate. Gasper figures to draw the better spot in the order, but Durbin has been on fire since a major overhaul in his swing mechanics. Durbin is up to a 146 wRC+ and .291 ISO in June. If Anthony Seigler draws the leadoff spot in the order, he belongs on this list as well. 

Coby Mayo (3B, BAL) & Jeremiah Jackson (2B/OF, BAL)

Analysis: Mayo has been incredible against left-handed pitching this season, including a .415 ISO. Six of his nine home runs have come off lefties despite having 94 fewer plate appearances against them. Jackson's 2B eligibility makes him a useful value option with a prime matchup against a low-K lefty. Tyler O'Neill and Blaze Alexander can also be included in this discussion. 

Cooper Pratt (SS, MIL) & Garrett Mitchell (OF, MIL)

Analysis: Pratt is off to a strong start to his big league career, with seven hits and three stolen bases in his first six games. Mitchell has a 93rd-percentile average exit velocity and 96th-percentile bat speed that have translated to a .204 ISO against righties this season. These two Brewers draw an elite matchup in one of the best home run parks in baseball. 

MLB DFS Top Stacks

Primary Stack: Boston Red Sox vs Ryan Feltner (COL RHP)

Why: Boston has been one of the worst offenses in baseball against right-handed pitching, ranking dead last with an 85 wRC+. With that said, they own the highest implied team total on the slate by a healthy margin as they draw an elite matchup against Feltner in Coors Field. 

Primary Stack: Milwaukee Brewers vs Brady Singer (CIN RHP)

Why: Milwaukee's 112 wRC+ against right-handed pitching ranks third in baseball. They draw an elite matchup against Singer, who has allowed an ISO above .240 to both sides of the plate and 2.4 HR/9. He has also posted a strikeout rate of just 17.1%. 

Primary Stack: Baltimore Orioles vs Sam Aldegheri (LAA LHP)

Why: Baltimore has struggled against lefties this season, but Aldegheri doesn't offer much resistance on the other side of the matchup, and the Angels' bullpen has also been bad. Aldegheri has walked nearly as many batters as he has struck out, and he posted a 7.24 ERA across 49 innings in Triple-A this season.  

"Contrarian" Stack: Colorado Rockies vs Jake Bennett (BOS RHP)

Why: The Rockies are drawing little ownership despite having the second-highest implied team total on the slate. Bennett has been good at limiting power in his brief career thanks to a 54% groundball rate, but he now has to deal with Coors Field. 

"Contrarian" Stack: Los Angeles Dodgers vs Zebby Matthews (MIN RHP)

Why: The Dodgers are another stack flying under the radar (other than Ohtani) despite having an implied team total above five runs. Their 124 wRC+ against righties ranks first in baseball. Matthews has posted a 4.78 ERA, allowing an 11.3% barrel rate and 1.7 HR/9 this season. Additionally, the Minnesota bullpen has posted the worst ERA in all of baseball. 

MLB DFS Lineups: Core MLB DFS Hitters & Pitchers

The "Chalk" (Popular)

The "Pivot" (Low

Owned)

The Winning Logic
Kay (SP, chalk value)Holmes (SP, lower owned)Holmes has significantly more upside than Kay, as he has been unlucky with strikeouts this season and faces a lineup that aligns well with his strengths. 
Red Sox (Chalk)Brewers (pivot stack)The Red Sox have been one of the worst offenses in baseball this season, while the Brewers have been one of the best. Both are in elite matchups. 
Duran + Abreu (chalk)Chourio + Bauers (lower owned)The Brewers are at almost identical price points as the Red Sox, and their matchup is every bit as good. However, the Brewers project to be far less popular. 

 

 

 

 

 

 

The foundation for every MLB DFS lineup you build today. These are the core MLB DFS picks by position across DraftKings and FanDuel.

  1. Gavin Williams (SP1)
  2. Kyle Bradish (SP2)
  3. Willson Contreras (Core Bat)
  4. Jackson Chourio (Core Bat)
  5.  Brice Turang (Core Bat)
  6.  Coby Mayo (Core Value Bat)
  7. Cooper Pratt (Core Value Bat)

Player Pool

$ Tier {{pos.alias}}

Stacks

{{stack.team.name}} {{player.name}}
DraftKings {{player.fantasy.price.value[8]}}-
Fanduel {{player.fantasy.price.value[6]}}-