Don’t look now, but it’s already time for the first Sunday Night Baseball game of the 2026 MLB season! These matchups have transitioned from ESPN to NBC and Peacock, and the first iteration of it features the #2 and #3 playoff seeds in the AL last season. So, let’s enjoy this series finale with our best Guardians vs. Mariners predictions for Sunday Night Baseball.

Along with top Guardians vs. Mariners picks for tonight, you’ll also see that we’ve hooked you up with a GUARANTEED 10x Novig Sportsbook promo code bonus!

🔥 Guardians vs. Mariners Predictions for MLB Sunday Night Baseball

With these AL squads splitting the first two games of their four-game series, we knew that this Sunday Night Baseball would be on that could decide the series winner. That may not seem like much just a few days into the season, but who knows, these Guardians vs. Mariners predictions could decide this year’s playoff seeding as well!

That said, entering the season, Seattle was favored to win the AL West, while Cleveland was only the third favorite to win the AL Central. Speaking of favorites, Bryan Woo & company one of the heaviest favorites of Saturday (which featured FIVE walk-offs), but it was Jose Ramirez and the come through for some MLB expert picks in extra innings!

Perhaps the home team could have used some JP Crawford production to get over the one-run loss, but he’s still going to be on the IL for tonight’s prime time game. We’ve got plenty of other guys to keep in mind to provide you with the best bet from our Guardians vs. Mariners predictions.

 

 

 

🏅 Guardians vs. Mariners Best Bet: Seattle Money Line (-132 at Novig)

With this being the fourth game of the series, it’s safe to say that we aren’t going to be seeing a battle of aces to close out the weekend. It’s Slade Cecconi and Emerson Hancock for Cleveland and Seattle, respectively, so we wouldn’t mind adding the over 7.5 runs to your Guardians vs. Mariners picks as well.

Cecconi is in his second season with The Land after starting two seasons in the desert with the Arizona Diamondbacks. He definitely showed signs of improvement after his time there, but is it enough? Not for our Guardians vs. Mariners predictions, and while we’re not going to consider Hancock elite either, Seattle should be more heavily favored at home.

That’s why you’ll want to use Novig’s commission-free lines (this is near -160 elsewhere), but more on that coming up. As for Hancock, while you won’t even see him listed in the rotation, the team gave him another taste at starting to close out last regular season, and he racked up seven K’s in just four innings.

Even if you don’t want to trust either starter, as much as we love Ramirez, Seattle still has the more complete lineup with Cal Raleigh, Julio Rodriguez, Josh Naylor and Randy Arozarena. It’s even a revenge game for Naylor to help us hit Seattle’s money line (-132 at Novig) as the best bet from our Guardians vs. Mariners predictions.

 

 

 

👀 How To Watch Guardians vs. Mariners MLB Sunday Night Baseball

We already let you know that these weekly featured matchups are no longer on ESPN, and you can see how to watch Guardians vs. Mariners MLB Sunday Night Baseball below:

  • Where: T-Mobile Park in Seattle, WA
  • When: 7:20 PM ET on 3/29
  • Watch on TV: NBC
  • Where to stream: Peacock

 

 

 

🔢 Guardians vs. Mariners Odds, Spreads, Total & Betting Lines

We said that you’ll want to use the latest Guardians vs. Mariners odds for Sunday Night Baseball at Novig Sportsbook, which you can see below:

 

 

 

⚾ Guardians vs. Mariners Injury Report & Starting Pitchers

These are two of the healthier teams in the MLB, but it’s always important to note any Guardians vs. Mariners injuries. Cleveland is pleased that the Tanner Bibee injury isn’t a serious one, and as for daily players, they’ve got who they need on the diamond and at the plate.

As for Guardians vs. Mariners injuries in Seattle, we already mentioned the most notable, which is JP Crawford. In terms of the rotation, Bryce Miller is starting the year on the IL, hence the Hancock start. Speaking of which, you can see the Guardians vs. Mariners starters for tonight below, and be sure to also bookmark our Fantasy Alarm MLB injury report! 

 

 

 

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