UFC 322 brings one of the most intriguing stylistic matchups of the year as striking phenom Jack Della Maddalena takes on the relentless wrestling pressure of Islam Makhachev. With championship implications on the line, this card offers several strong betting angles for both favorites and live underdogs.

Below are the best bets, fight-by-fight predictions, and a streamlined guide on how to bet these picks at DraftKings.

 

 

 

UFC 322 Predictions & Picks: Saturday, November 15th

Della Maddalena vs Makhachev (Main Event Pick)

Jack Della Maddalena’s boxing is among the sharpest in the division—tight combinations, elite shot selection, and dangerous counters. The key question: can he stop Makhachev’s chain wrestling and top control?

  • Best Bet: Makhachev by Submission +180

Makhachev should be able to takedown Della Maddalena, and Maddalena loves to turtle to try to get back to his feet, which exposes both his back for a rear naked choke, and his neck for a front choke.  When they are fresh, I don’t expect Della Maddalena to make a mistake, but once he gets tired, he could slip up, leading to the submission.

Erin Blanchfield vs Tracy Cortez

  • Best Bet: Blanchfield by submission +500

This is a rematch from years ago, when Blanchfield was only 19 years old, and she was almost able to lock up the submission back then.  Blanchfield is just now reaching her prime, and this is a great chance for her to make a statement, and the submission should present itself as both of these women like to take their fights to the ground.

Sean Brady vs Michael Morales

  • Best Bet: Brady by submission +400

This is another long-shot bet, but if Brady wins this fight, he has to hunt for the submission.  Morales is a quick, powerful striker, but he hasn’t faced someone who can wrestle like Brady.  Brady likely won’t get the submission early, so if you want to be extra greedy, you can bet that he gets the submission in R2/3.

 

 

 

How To Bet On My UFC Picks At DraftKings

Placing UFC bets at DraftKings is quick and easy:

  1. Download the DraftKings Sportsbook app or open it on desktop.
  2. Create an account (or log in).
  3. Find “UFC/MMA” under the sportsbook menu.
  4. Look for UFC 322 and click on each fight.
  5. Select your bet type: Moneyline, method of victory, round props, or same-game parlays.
  6. Enter your wager amount and confirm the bet slip.

 

 

 

How to Watch UFC 322 on ESPN, Della Maddalena vs Makhachev Saturday Night

  • Broadcast: ESPN / ESPN+ PPV
  • Date: Saturday, November 15
  • Main Card Start Time: 10 PM ET
  • Location: Madison Square Garden

Early prelims and prelims are usually streamed through ESPN+ before the PPV main card begins.

 

 

 

UFC 322 Odds & Score $300 Promo At DraftKings

New customers can access a Bet & Get-style promo where wagering a small qualifying bet unlocks up to $300 in bonus bets (promo availability varies by state).

How to get the offer:

  1. Sign up at DraftKings Sportsbook
  2. Make your first deposit.
  3. Place any eligible UFC bet.
  4. Receive your bonus bets, which can then be used on Della Maddalena–Makhachev props, round bets, or parlays.