It's a fireworks-ready AFC East tilt on Thursday Night Football as the Buffalo Bills host the Miami Dolphins at Highmark Stadium. Buffalo is gunning for 3-0, and Miami is fighting to avoid a 0-3 hole after a brutal start. Let's lock in some NFL TNF Player Prop Picks for tonight's matchup.

The Bills, as 12.5-point home favorites, should control the trenches with a run-first mentality led by James Cook. Meanwhile, Miami's explosive offense, powered by Tua Tagovailoa and Tyreek Hill, will test Buffalo's stout secondary in a classic divisional dogfight. 

We've zeroed in on the sharpest Dolphins vs. Bills player props, including Cook's rushing explosion, Joey Bosa's sack potential, and Cook's high-upside TD dart. These are the edges to target, let's cash 'em. Good luck with your own NFL TNF Player Prop Picks! 

 

 

 

Best NFL Thursday Night Football Player Prop Picks; Dolphins vs. Bills Player Props: James Cook Over 70.5 Rushing Yards

Miami's run defense got exposed last week, coughing up nearly 5.0 yards per carry to the Patriots and Rhamondre Stevenson. Week 1? Jonathan Taylor carved them up for 71 yards on the ground.

Now in Week 3, the Dolphins square off against Buffalo's run-heavy attack, staring down James Cook, who just torched the Jets for 132 yards on 21 carries in Week 2.

The Bills are 12.5-point home favorites, so expect them to dictate the pace early with the ground game, lean on it late to salt the win, and hand the rock to Cook in this heated divisional clash.

 

 

 

Dolphins vs. Bills Player Prop Bets: Joey Bosa 1+ Sack

We're grabbing plus-money value at +110 on Joey Bosa to notch a sack tonight, and while we typically hunt those safer 0.5 lines, this feels like a steal. 

Miami's O-line got shredded last week, surrendering five sacks to the Patriots in a home gut-punch, and they coughed up three more to the Colts in Week 1.

Bosa finally broke through with his first sack of the season against the Jets last week, and with a resume stacked with multiple 10+ sack campaigns, he's primed to erupt.

As 12.5-point home favorites, the Bills should force the Dolphins into obvious passing downs, dropping back often and teeing up Bosa for chaos.

 

 

 

Thursday Night Football Player Props: First Touchdown - James Cook

The anytime TD for Cook is sitting at -175, which is solid but meh. Why not swing for the fences on his first TD scorer line at +425 and turn a modest bet into a bankroll booster?

Cook's been a scoring fiend since last season, ripping off 16 rushing TDs and two receiving scores over 16 games. Fast-forward to 2025, and he's already punched in three rushing scores through the first two weeks.

Even with Josh Allen's cannon arm and rushing upside, Buffalo loves feeding Cook the rock in the red zone; he's their go-to hammer. As 12.5-point home favorites against a Dolphins D that's soft up front, expect Buffalo to grind it in early and often, giving Cook multiple cracks at paydirt. 

 

 

 

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