Get ready for an exciting Monday Night Football showdown in Week 6 as we dive into the best player prop picks for the games on October 13, 2025! 

With thrilling matchups and star players ready to shine under the primetime lights, our expertly curated prop bets highlight top performers, key stats, and favorable odds to help you make informed decisions for your betting card. 

Whether you're a seasoned bettor or just looking to add some extra excitement to the game, these picks are designed to maximize your enjoyment and potential payouts. 

Let’s break down the top player prop bets for this week’s MNF action!
 

 

Best NFL Monday Night Football Player Prop Picks: Kyle Pitts Over 41.5 Receiving Yards

The Bills' defense struggles significantly without Matt Milano, particularly in covering opposing tight ends.

With Milano sidelined, Kyle Pitts becomes a focal point. 

Coming off a 70-yard game against the Commanders and exceeding this total in Week 1 against the Buccaneers, Pitts has a season-low of 37 receiving yards. Tonight, with the Falcons at home after a bye, 41.5 yards is well within reach.

 

Bills vs Falcons Player Props: Josh Allen Over 35.5 Rushing Yards

Allen is known for his ability to make big plays on the ground, especially when he finds running lanes due to defensive coverage focusing on the pass and no receivers are open.

He's exceeded 35.5 rushing yards in three of his last four games, consistently getting 6-8 carries per game.

With the Bills facing the Falcons, who are coming off a bye week, Allen seems like a strong candidate to go over 35.5 rushing yards tonight on the road.

 

 

Bears vs Commanders Player Prop Bets: Rome Odunze Over 66.5 Receiving Yards

Odunze has emerged as the Bears' leading receiver this season, steadily developing a strong connection with QB Caleb Williams within the new Ben Johnson offensive scheme.

Coming off a bye week, the Bears are well-positioned for success against a vulnerable Washington Commanders secondary.

Odunze has consistently delivered for us this season.

 

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