There is no better way to kick off a long-awaited NFL season than with a Super Bowl rematch. Even if you aren’t a fan of the New England Patriots or Seattle Seahawks at all, every football fan wants action tonight. That’s why we have our NFL best bets for Wednesday Night Football for you! The ways to make NFL picks these days are all but infinite, and they’re the perfect addition to all your fantasy action.

Speaking of countless ways to make NFL predictions, we’ll also show you how to make them more valuable with a monster $1,000 Fanatics Sportsbook promo code bonus!

🔥 NFL Week 1 Wednesday Night Football Best Bets, Expert Picks & Predictions, 9/9

While this is the first game of the entire season to make NFL best bets for Wednesday Night Football, you’re going to want to have our picks for each and every game, which is why now’s the time to bookmark our NFL expert picks! Of course, leading up to the first full Sunday slate, it’s all about the standalone action, starting with this Super Bowl rematch.

Making NFL best bets for Wednesday Night Football is going to rely heavily on a combination of last year’s numbers plus speculation, so let’s talk about the matchup overall to lead into what we’re targeting for our best bet.

 

 

 

🏉 Wednesday Night Football Prediction for Patriots vs. Seahawks

While Super Bowl LX was over half a year ago at this point, most fans still don’t have any issue remembering that it was Sam Darnold and Seattle that came out on top. They had led from the jump with four field goals before we finally enjoyed some thrill in the fourth quarter, so hopefully we’ll pick up where we left off with NFL best bets for Wednesday Night Football.

Speaking of which, you’ll want to pair our top pick here with our overall Patriots vs. Seahawks predictions here. We say that because some fans prefer overall game markets to player props and vice versa, and we want you to be covered from all angles. That said, with two stellar defenses, for those who don’t find rooting for unders fun, player prop options can be few and far between.

Thankfully, we’ve been taking the time between the preseason and this game to do the digging for you, and with that comes the official top pick from our NFL best bets for Wednesday Night Football!

🏉 Patriots vs. Seahawks Best Bet for NFL Week 1: Hunter Henry Over 32.5 Receiving Yards (-115 at Fanatics)

Again, New England and Seattle are led by their defenses, despite what we could point out regarding their offenses. So, let’s just knock that out of the way - Drake Maye was a top MVP candidate, Jaxon Smith-Njigba was the Offensive Player of the Year, AND the Pats now have A.J. Brown, yet we’re focused on a TE with our NFL best bets for Wednesday Night Football.

That’s because the Super Bowl grudge match for three and a half quarters was the culmination of what we saw all season from these defenses. New England allowed the ninth-fewest passing yards per game, ninth-fewest passing TDs overall, sixth-fewest rushing yards per game, and the fourth-fewest rushing TDs overall.

Similarly, Seattle allowed the 10th-fewest passing yards per game, sixth-fewest passing TDs overall, third-fewest rushing yards per game, and the second-fewest rushing TDs overall. That was a lot of rankings at once, but the spot where both teams were “only” mediocre, it was against the TE position, and it’s the Patriots' that has our attention for NFL best bets for Wednesday Night Football.

Hunter Henry averaged over 45 receiving yards per game, and that was reduced with a few outliers of single-digit performances. To start the season, he had 27 to 90 receiving yards in six of seven games (meme away), and to end it, he had between 35 and 115 receiving yards in six of seven games (keeping the meme alive)!

With Seattle allowing the sixth-most receiving yards to the TE position last year, we love focusing our NFL best bets for Wednesday Night Football on Hunter Henry over 32.5 receiving yards (-115 at Fanatics).

 

 

 

🔢 Best NFL Player Prop Bets & Picks Today for Wednesday Night Football

From overall NFL picks to our ultimate favorite spot, let’s expand on the fact that there is no shortage of ways to lock in more action. Here are some top Patriots vs. Seahawks player props for tonight at Fanatics Sportsbook:

Anytime Touchdown:

Passing Yards (Over/Under):

  • Drake Maye: Over 225.5 (-120) vs. Under 225.5 (-110)
  • Sam Darnold: Over 225.5 (-115) vs. Under 225.5 (-115)

Rushing Yards (Over/Under):

Receiving Yards (Over/Under):

📊 Fantasy Alarm NFL Best Bets Record 

A new season is just now getting underway, so until we can add our NFL best bets for Wednesday Night Football and more to it, here is our Fantasy Alarm NFL best bets record from the 2025-26 season…

  • Overall record: 427-390
  • Units: 102.72u
  • ROI: 11.72%

 

 

 

💲 How to Make NFL Best Bets for WNF at Fanatics & Claim Your $1,000 Bonus w/ Code ALARMFAN

If you’re ready to make our successful numbers above and all future NFL predictions more valuable, here’s how to score a colossal $1,000 Fanatics promo code bonus:

  1. Click here 👈🏼 to create a new Fanatics account
  2. Enter our exclusive Fanatics NFL promo code ALARMFAN
  3. Make a deposit of at least $10
  4. Place a wager of $1+ on any market with odds of -500 or longer on day one
  5. If the wager loses, receive up to $100 in FanCash within 72 hours
    1. Repeat every day for 10 consecutive days to earn up to $1,000 in total FanCash!

Of course, you can start making picks on any matchup, not just our NFL best bets for Wednesday Night Football. If that sounds good to you, just 🔗 use this link 🔗 so that no special Fanatics promo code will be needed!