As already mentioned in today's MLB DFS Playbook, we have a pretty consistent across the three major sites (DraftKings, Yahoo, FanDuel). The Padres, led by the duo of Jurickson Profar and Manny Machado, are my top stack of the day, but I also like the Astros and Rangers as options. We appear to be relatively free of mlb weather concerns outside of one game, but keep an eye on the latest MLB weather report before making daily fantasy baseball lineups. Don't forget to check out the MLB lineups page before locking in MLB daily fantasy lineups. Plus, use the MLB daily projections, our MLB DFS Optimizer, and the rest of our MLB DFS lineup tools before setting your lineups. Now let's look at our MLB DFS top picks for Friday, September 23.