TWO more MLB home run picks cashed on the same night for us! That’s the second time in just 3 days to make it 5 total hits in just 4 days. So, let’s keep the good times rolling with our best MLB home run picks for today, which are built around the matchups where the numbers point toward power before any of the big names have thrown a pitch. There are also plenty of afternoon games before we even see Ohtani for MLB home run predictions!

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⚾ Top MLB Home Run Picks for Today

Wednesday's full card gives us plenty to dig through for our best MLB home run picks for today. Beyond the marquee names, the earlier pitching matchups are where the real plus-money lives. Swing by our MLB expert picks for the full slate breakdown. Here are the three names leading our top MLB home run predictions for 5/27:

 

 

🔥 Best Matchups for Home Runs Today, 5/27: Ballpark Factors & Weather Impact

The 1 PM ET opener in Toronto and a handful of early afternoon starts make our MLB weather report worth a look before locking in any best MLB home run picks today. Miles Mikolas in Cleveland, Walker Buehler in San Diego, and Connelly Early in Boston are among the pitching names worth flagging for HR/FB tendencies across the Wednesday card. Here is how our three featured best MLB home run picks for today break down:

Vinnie Pasquantino (+576)

The New York Yankees absolutely just teed off on the Kansas City Royals last night (Ben Rice was our only pick that DIDN’T hit), so you already know that lefty could be a prime target. Speaking of lefties, the Royals are starting Noah Cameron tonight with more ideal conditions for MLB home run picks in KC.

However, our pick is going to surprise you, but it’s as valuable as it gets. With Gerrit Cole back on the bump for the Bronx Bombers, the Royals' lineup may be faded by some, but not us. Cole had a great first outing, but it’s just that - only the first one. We’ve seen him even in midseason form have games giving up multiple dingers in the 1st inning alone.

While Bobby Witt, Jr. recently cashed for us, we’re on the KC lefty. He’s fantastic at avoiding swing-and-misses and contact with Cole can go a long way. So, we’re starting our best MLB home run picks for today with Vinnie Pasquantino to hit a HR (+576 at DraftKings).

Nick Kurtz (+325)

Next up is a favorite target of ours, which is the Sacramento ballpark. The home of the Athletics these days has been consistently great for homers, which we know has been beaten to death. With how much the Seattle lineup has struggled against lefties this year and the A’s starting Jeffrey Springs, we’re focused on the home team with our top MLB home run picks today.

They’ll be facing Logan Gilbert, who can be as hot-and-cold as it gets. In his four starts this month, he’s had games allowing 3 and 4 homers between solid starts, and he’s due for another one of those rough outings. You already know the deal here - it’s always a toss-up between Shea Langeliers and our target.

With the lefty vs. righty matchup, we have a slight lean to the southpaw (like Matt Olson cashing last night), so we’re adding to our best MLB home run picks for today with Nick Kurtz to hit a HR (+325 at FanDuel). 

Michael Busch (+505)

Ok, after a more popular target, we’re going to risk our hot streak with another valuable play rather than an easy way out. The Chicago Cubs' lineup needs to get back on track to get out of this slump, so why on Earth are we picking this spot to do it? Pittsburgh Pirates starter Bubba Chandler just racked up 11 K’s, yet we’re picking on him with our MLB home run picks.

He did just have that remarkable outing, but in the 3 starts prior, he had just 2, 3, and 4 strikeouts. Chandler throws heat, and when he doesn’t have elite control, his fastball gets absolutely blasted out of the park. It feels as though the Cubs' first baseman is the one trying to keep the team’s hopes alive right now, so he’s our target.

Again, it’s not going to be the one that a ton of fans love, but let’s take it while we’re feeling our MLB home run picks and lock in Michael Busch to hit a HR (+505 at Novig). 

🚀 Longshot Home Run Picks Today

With Ohtani on the mound late at Dodger Stadium, the plus-money on opposing hitters in that game deserves a look, given how much they will be doubted. Even still, here is where we see the most value for an MLB longshot home run pick:

Let’s not wait at all for a potential monster payout. Nationals vs. Guardians is one of the day’s first games, and we get to pick on Miles Mikolas and the awful Washington bullpen. He may not be known for power, but it’s a flyer for a reason - Bazzana is our best MLB longshot home run pick for today!
 

 

 

💲 Today’s Best MLB Home Run Parlay

Stack our featured targets or mix in a fresh name from Wednesday's card alongside one of our best MLB home run picks for today:

Three featured best MLB home run picks for today, a longshot, and a full Wednesday slate to enjoy before a lighter Thursday. No matter how you approach our angles above, let’s make it feel like a Friday night!