Wednesday's MLB slate has a little bit of everything - early afternoon action kicking off just after noon, a wave of evening games, and one of the most anticipated pitching appearances of the season with Shohei Ohtani taking the mound in San Diego. With several series on the verge of wrapping up, our best MLB home run picks for today are ready to cash in on it.

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⚾ Top MLB Home Run Picks for Today

Wednesday's 15-game slate gives us plenty to dig into for our best MLB home run picks for today. Of course, this article is all about the plus-money - check our MLB expert picks for additional markets as well. As for the long ball, here are the three names leading our top MLB home run predictions for 5/20:

 

 

🔥 Best Matchups for Home Runs Today, 5/20: Ballpark Factors & Weather Impact

With afternoon games on the menu, our MLB weather report is essential reading before locking in any MLB home run picks - midday conditions at several parks can shift significantly by first pitch. 

The pitching slate has some notable names worth flagging: Shohei Ohtani takes the ball in San Diego, Jack Leiter heads to Coors Field, and Kyle Harrison vs. Edward Cabrera in Chicago is a matchup worth circling for power on both sides. Let’s see if any of those made the cut for our best MLB home run picks today.

Mike Trout (+343)

Two of the best HR environments for today’s all-day slate are Philly and the Bronx, so if you want the “square” targets, both Aaron Judge and Kyle Schwarber are set up for success. After all, we’ve targeted them each of the past two days, so you KNOW they’re going yard today. That said, we’ve got more variety for our best MLB home run picks for today.

We’re starting with the other side of the country in LA. The Dodgers are on the road against the San Diego Padres, so that means we’re looking at the Athletics vs. Angels series. Frankly, both lineups have solid opportunities to be part of our MLB home run picks, but with Jack Kochanowicz being more of a groundball pitcher, we’re picking on Aaron Civale.

That means Mike Trout, but if you want more value, we also like Zach Neto here. But, just to start our best MLB home run picks for today, we’ll take Mike Trout to hit a HR (+343 at Novig).

Elly De La Cruz (+410)

Ok, we need to quickly spin things back from a late game to the very first game of the day. Both Andrew Abbott and Aaron Nola provide great opportunities, hence our mention of Kyle Schwarber above. However, there is yet another target we’re going to provide you with to add to our top MLB home run picks today.

It’s on the Cincinnati side of the matchup to exploit Aaron Nola’s 17.6 HR-to-fly-ball ratio. That’s great news for the very warm Philly afternoon weather and 10 mph winds. If you want to stick with a pure lefty, JJ Bleday is in play, but we’ll ride with the switch-hitter. De La Cruz has also been a .302 hitter vs. righties this season and has been Cinci’s best vs. curveballs.

That’s what Aaron Nola prefers to throw, so let’s add to our best MLB home run picks for today with Elly De La Cruz to hit a HR (+410 at FanDuel).

Mickey Moniak (+455)

So the Rangers just rolled the Rockies 10-0 last night and now get to face Kyle Freeland today. That means more Texas long balls could be on the menu with his HR/FB ratio, but at the same time, they aren’t exactly elite vs. lefties this season. So, we’re going to add to our top MLB home run picks today with the home team instead.

Thankfully for Colorado, Rangers starter Jack Leiter has a HR/FB ratio that is nearly as bad as Freeland’s. More good news for the Rockies is that he’s a righty, as they’ve been very prone to striking out against southpaws this season. Leiter sticks with the fastball, so we don’t need to think about anything fancy here.

Therefore, for the very first time this season, we’re double-dipping by adding to our best MLB home run picks for today with Mickey Moniak to hit a HR (+455 at Caesars).

🚀 Longshot Home Run Picks Today

Wednesday's slate has a few spots where just “normal” plus-money isn’t enough - particularly with Coors Field and a couple of hitter-friendly environments in play. Here's the longshot we're targeting for today's big potential payout:

We’ve circled back to LA for this pick. The same stands for Aaron Civale, and the second baseman actually has a very solid hard-hit rate. The sample size isn’t as significant as the likes of Mike Trout, but remember - it’s our MLB home run LONGSHOT pick for today!

 

 

 

💲 Today’s Best MLB Home Run Parlay

Stack our featured targets or mix in a name from Wednesday's deep card alongside one of our best MLB home run picks for today:

You’re now locked and loaded with several approaches to an all-day slate! Whether you use just one of our top MLB home run picks today or mix and match for a supreme, for-fun parlay, make the most of it all!