Few events in sports stir up the same level of excitement, rivalry, and cultural significance as Ohio State vs. Michigan. "The Game" is more than just a rivalry — it’s a generational divide, a year-round obsession, and that one special afternoon each year where even the stakes for a national title seem less important. And even though Ohio State heads into Week 14 undefeated and ranked first in the nation, that has never guaranteed an easy time in Ann Arbor.

Michigan has won the last four matchups in this rivalry, including last year’s surprising 13–10 victory that knocked the Buckeyes off their path towards a Big Ten championship. Now, Ohio State comes in as a double-digit favorite, healthier, with more depth, and once again seen as the superior team overall. This means our #1 Ohio St. vs. #15 Michigan picks think they roll, right?
 

 

 

#1 Ohio St. vs. #15 Michigan Predictions for College Football Week 14, Saturday, 11/29

Ohio State has been dominating their opponents this season with the best defense in the nation and one of the most effective offenses around. The Buckeyes rarely find themselves in tight spots late in the game, haven’t faced much challenge, and they hardly ever seem flustered or anxious. The Buckeyes come out on top because they’re simply more skilled, more dynamic, and handle situations better than almost every team they face. 

But here’s the catch: nearly none of their opponents are like Michigan. With the Wolverines playing at home, a young QB gaining confidence, and the betting market leaning towards +10.5? That’s where #1 Ohio St. vs. #15 Michigan predictions start to get really intriguing.

 

 

 

#1 Ohio St. vs. #15 Michigan Spread Pick: Wolverines +10.5 (-120 at FanDuel Sportsbook)

The current spread is Ohio State -10.5, and given that this rivalry is known for flipping the script on logic, momentum, and rankings, that line seems a bit high. Sure, the Buckeyes are undefeated and have the edge in talent. Yes, they boast the top scoring defense in college football. And yes, Julian Sayin has been running the offense with impressive precision behind a top-notch offensive line.

However, the notion that this will turn into yet another Buckeye blowout like we’ve seen throughout the season? That’s the part that doesn’t quite sit right. Michigan might not be flawless, but they’ve managed to stay undefeated at home, and that stadium really changes the game.

Even in seasons where Michigan seems outmatched on paper, the Big House helps level the playing field. And while Ohio State has stepped up their ground game and played solid defense, this is their first real four-quarter challenge in a tough environment.

Plus, all the pressure is on Ohio State. Ryan Day has a 1–4 record against Michigan. The Buckeyes haven’t taken down their rival since 2019. Every play, every crucial moment, every red-zone opportunity will feel more intense for the visiting team.

Offensively for UM, their play up front may not be as dominant as the Joe Moore Award-winning units from the Harbaugh era, but it’s still tough, disciplined, and designed to control the game clock.

True freshman Bryce Underwood is stepping up to the challenge, too, and his mobility adds a new element that Michigan missed last year. If he can steer clear of the major blunders that freshman QBs often make in rivalry games like this, he can help keep the Wolverines competitive.

This narrative feels all too familiar. Last year, bettors and analysts were all over Ohio State as well. They had the talent, the stats, and a solid defense. Michigan was also putrid up to that point. But the Wolverines somehow found a way to pull off a 13–10 victory.

Once again this year, the public is rallying behind the Buckeyes. And once more, Michigan is being overlooked because the matchup “should” favor Ohio State. But here’s the thing about rivalry games: The team getting double digits at home usually ends up being the smarter bet.

Ohio State is likely to win. But by 11+ points? In this rivalry? With Michigan getting better on offense, playing with confidence, and supported by one of the loudest home crowds in college football? “Not so fast, my friend,” as our #1 Ohio St. vs. #15 Michigan predictions echo Lee Corso.
 

 

 

How To Watch #1 Ohio St. vs. #15 Michigan College Football Week 14

  • Date: Saturday, November 29, 2025
  • Time: 12:00 PM ET
  • TV: FOX
  • Location: Michigan Stadium – Ann Arbor, MI

 

 

 

#1 Ohio St. vs. #15 Michigan Odds, Spreads, Total & Betting Lines

We’ve just released our #1 Ohio St. vs. #15 Michigan predictions. Now, let’s take a look at the latest #1 Ohio St. vs. #15 Michigan odds for this matchup from FanDuel Sportsbook:

  • Money Line (ML): Buckeyes -390 | Wolverines +310
  • Spread: Buckeyes -10.5 (-104) | Wolverines +10.5 (-118)
  • Over/Under (O/U): 43.5 (O: -115 | U: -105)

 

 

 

#1 Ohio St. vs. #15 Michigan Injury Report & Latest News

Ohio State Injury Report

  • M. Roy (DL) – Questionable, Undisclosed
  • J. Carter (DL) – Questionable, Undisclosed
  • A. Tounkara (DL) – Questionable, Undisclosed
  • L. George (DL) – Questionable, Undisclosed
  • C. Tate (WR) – Questionable, Undisclosed
  • M. Maggs (QB) – Questionable, Undisclosed
  • Q. Porter (WR) – Questionable, Undisclosed
  • M. Hartford (S) – Questionable, Undisclosed
  • D. Jones (WR) – Questionable, Undisclosed
  • J. Smith (WR) – Questionable, Undisclosed

Michigan Injury Report

  • M. Bredeson (TE) – Questionable, Foot
  • S. Morgan (WR) – Questionable, Undisclosed
  • E. Hausmann (LB) – Questionable, Undisclosed
  • J. Haynes (RB) – Questionable, Foot
  • E. Link (OG) – Questionable, Undisclosed
  • R. Moore (CB) – Questionable, Undisclosed
  • H. Hansen (TE) – Questionable, Undisclosed
  • J. Taylor (WR) – Questionable, Undisclosed
  • C. Charleston (WR) – Out, Undisclosed
  • D. Baxter (DL) – Out, Undisclosed
  • J. Hood (LB) – Out, Undisclosed
  • D. Johnson (RB) – Out, Undisclosed
  • I. Stewart (WR) – Out, Undisclosed
  • A. Babalola (OG) – Out, Knee

 

 

 

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