Need the best PrizePicks NFL picks today to close out Week 3? The 2-0 Eagles travel to Soldier Field for a game that will feature Case Keenum making his first start of the season with Caleb Williams sidelined, after Tyson Bagent filled in during relief last week. Below, we cover our favorite PrizePicks NFL picks for this Week 3 finale, backed by player projections and the key matchups shaping each pick.

Eagles vs. Bears: Game Outlook & Key Matchups

Chicago may be down to Case Keenum at quarterback, but its backfield duo of D'Andre Swift and Kyle Monangai has been the story of its offense, while Philadelphia brings a red-hot receiver room that's given the Bears' secondary problems already this season. Let's break down the PrizePicks plays we like most for this matchup.

 

 

 

Best PrizePicks NFL Picks for MNF, Week 3

Kyle Monangai NFL PrizePicks Pick: Higher 39.5 Rushing Yards

Through two games, Monangai has rushed for 100 yards and a score on just 10 carries in the opener, then added 47 more on 10 carries in Week 2, good for 147 yards and 7.4 yards per carry on the season. He carries no injury designation into Monday night and remains firmly established as Chicago's 1B behind D'Andre Swift in a true two-man rotation. With Case Keenum likely starting at quarterback, look for the Bears to lean on the ground game the way they did in their last meeting with Philadelphia, when Chicago ran for 281 yards as a team. Clearing 39.5 rushing yards looks very doable for a back averaging better than 7 yards a carry.

Dontayvion Wicks NFL PrizePicks Pick: Higher 41.5 Receiving Yards

Since Philadelphia traded for him this offseason, Wicks has been a revelation, going for 73 and then 74 receiving yards in his first two games catching passes from Jalen Hurts. He already rates 16th in the league against man coverage per PFF, and Chicago plays man coverage at the highest rate of any defense in football, a matchup made for him. With DeVonta Smith soaking up extra attention and safety help, Wicks should keep drawing single coverage against a Bears secondary that's had trouble at outside corner all season. Clearing 41.5 yards for a third straight week looks very attainable.

PrizePicks NFL Player Projections for Eagles vs. Bears

Both of these plays lean on the same framework behind Fantasy Alarm's Weekly Player Projections, which generates a projected stat line for every player on the slate by weighing expected pass and rush volume, touchdown probability, and matchup context rather than just last week's box score. That's the same process that pointed us toward Monangai and Wicks as our top plays for this game, and it refreshes throughout the week as news, weather, and depth charts shift. Fantasy Alarm All Pro members get the full weekly breakdown for every player in every game, not just the two we're highlighting here. If you want the complete picture behind every PrizePicks pick we make, upgrading to All Pro is the fastest way to get it.

 

 

 

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