Get ready for an action-packed NFL Sunday on September 21 with PrizePicks, where you can craft your ultimate fantasy lineup using expert player projections. 

Whether you're eyeing high-scoring matchups or breakout performances, our curated picks highlight key projections for top performers across the league, think explosive pass yards, rushing totals, and receiving yards that could define your entry. 

To kick things off, don't miss this standout promo: Patrick Mahomes' passing yards projection is slashed to just 0.5, making it an unbeatable anchor for your lineup. 

Dive into our top selections below and build entries that maximize your fantasy edge.

PrizePicks NFL DFS Picks for Sunday NFL Week 3, 9/21: NFL DFS Projections

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Jaxon Smith-Njigba PrizePicks NFL Pick: More Than 73.5 Receiving Yards

JSN has been an absolute monster to begin the season for the Seahawks, totaling 227 yards over the first two games of the year in matchups against the 49ers and Steelers.  

In Week 3, the Seahawks are back home against a New Orleans Saints team that many figure to be the worst team in football this season.  

While the Seahawks are home favorites and likely will look to run the football for most of the fourth quarter as they close this one out, I’m still projecting JSN to get things going early for this Seattle offense.  

If you want to even look for a boosted payout, you can look at his 0.5 touchdown projection as well, as I think JSN finds the end zone for the first time this season this weekend.

 

 

 

Kyren Williams PrizePicks NFL Pick: Less Than 3.5 Yards First Carry

So, we'll know pretty quick as we look at the under 3.5 yards projection for Kyren Williams' first rushing attempt.  

Williams is only averaging 3.8 yards per carry on the year and now will face one of the best defensive fronts in the NFL in the Philadelphia Eagles.  

Running into the middle of the Eagles defensive line is rarely effective as long as Jalen Carter isn’t getting ejected, and we’ve seen the Eagles hold both Javonte Williams to 3.6 yards per carry, Isaiah Pacheco to 2.2 yards per carry, and Kareem Hunt to 3.9 yards per carry.  

Just feels like a pretty solid pick that Williams gets three or fewer yards on his first rushing attempt this weekend.

 

 

 

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