What a spectacular way to wrap up our first Sunday of the 2025 NFL season – Buffalo Bills versus Baltimore Ravens on Sunday Night Football. And what an opportunity for us to build up our PrizePicks bankrolls with some NFL Pick Em plays.

These two AFC juggernauts have done battle plenty of times and with a pair of MVP quarterbacks in Josh Allen and Lamar Jackson we are expecting fireworks once again. Both have strong weapons and this game is expected to be another instant classic. Let’s dive in and see which NFL pick ‘em options are best for Sunday.

PrizePicks NFL DFS Picks for Sunday Night Football, 9/7: NFL DFS Projections

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Josh Allen PrizePicks NFL Pick: More than 0.5 Rush + Rec TDs

While every year we hear head coach Sean McDermott say he wants to limit Allen’s rushing attempts, the touchdown runs keep on coming. Offensive coordinator Joe Brady keeps the play-calling pretty conservative once he gets inside the green zone. He’ll either call for a handoff to James Cook or he’ll call a designed run for Allen. He doesn’t want the ball in the air that far into the opponent’s territory and risk not coming away with points. Allen will certainly oblige.

 

 

Derrick Henry PrizePicks NFL Pick: More than 0.5 Rush + Rec TDs

Henry punched it into the end zone in 14 of the 18 games he played last year and after resting up the entire preseason, we expect him to pick up right where he left off. There’s really no analysis needed here. Henry is an absolute beast and when the ball gets inside the 10-yard-line, the handoffs to Henry are the preference.

 

 

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