Welcome to college football Week 8 with a ton of interesting matchups, players to watch, and picks to make before Saturday's games kick off. Check out some of these CFB PrizePicks top plays and college football picks and enjoy all the action for Saturday's Week 8 slate. Tulane QB Michael Pratt headlines our CFB Week 8 picks as the Green Wave enter the AP Top 25 for the first time in nearly 25 years. If you're building CFB DFS lineups or making college football betting picks, mix in some of these player props to get full exposure. Be sure to check out our college football weekly projections to fine tune those CFB bets and props. Plus, don't forget to use the CFB DFS Playbook and watch the College Football DFS video preview while entering college football daily fantasy lineups. Let's dive in and look at my top CFB PrizePicks plays and picks for college football Week 8 on October 22nd.


College Football PrizePicks CFB Top Picks Week 8 Saturday

Michael Pratt, Tulane – OVER 270.5 Pass Yards

Tulane has entered college football's AP Top 25 for the first time in 24 years with a 6-1 record to begin the season. The Green Wave will try to prove the ranking right with this week's matchup against Memphis. For Tulane QB Michael Pratt, it's a very favorable matchup against a defense that's allowing 301.4 passing yards per game (127th nationally) and 39.1 pass attempts per game (123rd). Five of seven opposing QBs have gone over 270.5 passing yards against Memphis this season. The only ones that didn’t were Navy’s QB (in a triple-option offense) and Temple’s QB (in one of the worst offenses in college football). 

Meanwhile, Pratt has looked good in the past two games after sitting out Week 5 with an injury. He’s thrown for 326 and 329 yards with 34 and 35 attempts, respectively. Though Pratt has gone over this line just three times in six games played, two of those under's are understandable. One was on the road against Kansas State and the other was in a blowout win over UMass in Week 1. 

Sean Tucker, Syracuse – UNDER 87.5 Rush Yards

In last year’s meeting against Clemson, Tucker racked up 157 rushing yards as Syracuse nearly pulled off the upset. You can bet that the Tigers defense has been reminded of that stat line all week as it preps for this rematch. If Clemson wants to avoid the loss this time around, it has to shut down Tucker and the run game while forcing ‘Cuse to beat them through the air. Per usual, the Clemson rush defense is one of the best in college football, allowing only 84 rushing yards per game (fifth-best in FBS). No opposing running back has rushed for 80+ yards against the defense this season. 

Granted, the Tigers haven’t yet faced a back as good as Tucker, but the numbers speak for themselves. Yes, Tucker has gone over this mark in four of six games this year while being a workhorse for Syracuse. Still, he also hasn’t faced a defense as good as Clemson’s. Plus, he was held to only 42 yards against Purdue’s top-20 rush D. 

Dae Hunter, Liberty – OVER 70.5 Rush Yards

This is a bit random because the casual college football fan may not know who Dae Hunter is or even pay attention to Liberty outside of Malik Willis last season. Still, the numbers and trends are impossible to ignore here. Hunter has gone over 70.5 rushing yards in five straight games and he has at least 62 rushing yards in every contest this season. The Liberty lead back is also averaging 6.3 yards per carry in 2022. Yes, this is a slight step up in competition having to face BYU. However, the Cougars' rush defense is allowing 187.14 rushing yards per game (114th in FBS) and 4.47 ypc (97th) this year. Plus, five straight opposing lead backs have gone over 70.5 rushing yards against BYU. Liberty is a 7-point underdog this week, but Hunter should be plenty involved with this favorable matchup and a game total at 58 points.

Ja’Tavion Sanders, Texas – OVER 38.5 Receiving Yards

While Quinn Ewers, Bijan Robinson, and Xavier Worthy dominate the national headlines, Ja’Tavion Sanders has been a great secondary weapon in the Texas offense this season. The tight end has emerged as a big part of the Longhorns’ attack as opposing defenses key in on Robinson and Worthy. He’s also been a top red zone target for Ewers in the passing game lately. Sanders has 40, 78, 71, and 37 receiving yards over the past four games, making this line a tad too low. Now Texas gets a favorable matchup against a shaky Oklahoma State secondary that’s allowing 301 passing yards per game (126th in FBS). Plus, Ewers may lean on Sanders at times for easier completions in this road environment.  


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