Looking for the best Underdog Fantasy MLB picks today? Our Underdog MLB Pick'em predictions for Tuesday, April 7, 2026, spotlight two pitcher strikeout props worth targeting on tonight's board. Cam Schlittler and Jacob Misiorowski both come with clear situational edges backed by dominant early-season form, elite stuff, and matchup data that points firmly in one direction. Here is the full case for where we land on both and why the numbers are set up the way they are.

What are the Best Underdog MLB Pick'em Picks Today?

Tonight's two best Underdog Fantasy MLB Pick'em plays are both pitcher strikeout props featuring two of the most electric arms in baseball, facing opponents that set up well for big punch-out totals. Read below for the complete analysis on each.

 

 

 

Cam Schlittler Higher (6.5 Strikeouts)

The argument for Schlittler is simple: he is pitching as well as anyone in baseball right now, and he is doing it against a lineup that cannot make consistent contact against quality stuff. Through his first two starts of 2026, he has thrown 11.2 scoreless innings with 15 strikeouts and zero walks, becoming the first Yankee to open a season with back-to-back starts of at least five scoreless innings and seven strikeouts. The velocity is sitting in the upper 90s on his four-seamer, and his cutter has taken a significant step forward, adding nearly five miles per hour and dramatically improving shape compared to last season. The result is a pitcher who can miss bats with multiple pitches to multiple parts of the zone.

The Athletics are the right opponent for a big strikeout night. Oakland is striking out against right-handed pitching at a nearly 30 percent rate, the highest mark in baseball, making this one of the cleanest matchups a strikeout-heavy starter could draw on the Tuesday slate. That kind of team-wide strikeout profile feeds a pitcher like Schlittler, who is already in the 80th percentile or better in strikeout rate, chase rate, and walk rate. Facing the team punching out at the highest rate in the sport, Schlittler's power arsenal makes seven strikeouts in a home start at Yankee Stadium a realistic baseline. Take Schlittler higher.

Jacob Misiorowski Higher (6.5 Strikeouts)

Misiorowski is a different animal than almost any pitcher in baseball right now. The 23-year-old Milwaukee ace topped 101 mph in his Opening Day start and generated 19 swings and misses on his four-seamer alone in that outing, finishing with 11 strikeouts across five innings against the White Sox. In his follow-up start, he added seven more, giving him 18 strikeouts across 11 innings with a 2.45 ERA. His slider sits at 94.3 mph, a legitimately extraordinary number for a breaking ball, and the combination of that offering with a triple-digit fastball gives him as high a strikeout ceiling as any starter in the National League.

Fenway Park is not a pitcher-friendly environment, but tonight's matchup against the Red Sox sets up extremely well for Misiorowski's strikeout total. Boston ranks third in baseball in strikeout rate against right-handed pitching to open the season at 29 percent, meaning this lineup is already getting punched out at one of the highest rates in the sport. Longer counts against a pitcher generating this many swings and misses ultimately produce more opportunities for strikeouts, not fewer, and facing a lineup checking in at 29 percent against right-handed pitching removes the biggest variable from this play. Take Misiorowski higher and ride the hottest young arm in the National League.

 

 

 

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