The 2026 MLB season rolls with another full slate of games. Let’s dive into the MLB Best Bets Today for Saturday, April 11th. We have all-day baseball on tap and plenty of ways to go for our MLB picks. Enjoy these MLB predictions as you lock in your own bets ahead of today’s games. Note that all odds and betting lines are accurate as of this writing, but are always subject to change. 

MLB Picks, Predictions & Best Bets Today, 4/11

Our MLB best bets today begin with an interleague matchup between the Boston Red Sox and St. Louis Cardinals. Our MLB picks also feature Kodai Senga and the New York Mets, who host the Athletics on Saturday afternoon. Check out even more MLB predictions below, including some player props and other game picks. Good luck! 

 

 

 

Red Sox vs. Cardinals Prediction: Saturday, April 11th

Ranger Suarez was one of the biggest free-agent pitcher signings this offseason. Yet, the left-hander has been slow to get going for the Boston Red Sox. He has an 8.64 ERA and 1.92 WHIP through his first two starts, allowing four runs in both outings. Maybe Suarez turns it around soon, but a sneaky-tough matchup against the St. Louis Cardinals looms this weekend.

The Cardinals are hitting well against left-handed pitching thus far. They have a .359 wOBA (4th in MLB), .271 batting average (3rd), 16.9% strikeout rate (4th), and 11.3% walk rate (9th) in the split. St. Louis is also in the top 10 in runs scored this year. It’s still early, but it's also encouraging for the young lineup. 

Suarez could run into trouble on the road here. His early-season struggles also come after shaky numbers in the spring. Suarez posted an ugly 11.20 ERA across his five outings in the World Baseball Classic and Spring Training, including eight runs allowed in his last spring outing. The Boston southpaw has now begun the regular season with 13 hits allowed compared to just five strikeouts over his pair of starts. The lack of swings and misses can be an issue against St. Louis. 

While the Cards do put up some runs, so too can the Red Sox in this matchup. St. Louis starter Kyle Leahy has a 5.40 ERA and 1.80 WHIP across his two starts so far. The right-hander is making the transition to the starting rotation after spending last year in the bullpen. It’ll likely take some time before we can trust Leahy, if at all. 

The Cardinals’ righty had a shaky 4.58 ERA during Spring Training with mixed results. He had a pair of scoreless outings, but also gave up four runs apiece in two others. We saw those issues when Leahy allowed four runs on eight hits to the Mets in his first start of this season. It’s also a bit worrisome that he has the same number of walks as strikeouts (5). 

Admittedly, the Boston offense has underwhelmed this year. The lineup is also below average against right-handed pitching so far (.303 wOBA, 91 wRC+). Still, the arrow may be pointing up. The Red Sox are averaging 5.0 runs per game over the past four contests. A matchup against Leahy can help the offense wake up more. 

Let’s take the over for the full game. We should get some runs on both sides to factor into a higher-scoring contest. Plus, we have a pair of below-average bullpens involved. The St. Louis relievers have a 5.05 FIP this year (25th in MLB), while Boston’s pen has a 4.89 FIP (23rd). 

 

 

 

Athletics vs. Mets Prediction: Saturday, April 11th

It’s been an up-and-down start to the season for the New York Mets. They’re 7-7 over the first two weeks and the offense has mustered only three runs over the past three games. Even so, let’s back them on Saturday at home against the Athletics. The pitching matchup certainly favors the home squad. 

Kodai Senga gets the start for New York. The right-hander has been solid in his first two starts, with a 3.09 ERA and a 16:5 K:BB ratio across 11.2 innings. He posted a 1.86 ERA and 0.72 WHIP during Spring Training, and it seems he’s carried that success over into the regular season. 

Senga is an intriguing pitcher to back this year. He was shaky at the end of last season after returning from a month-long injury. The Mets’ starter looks healthy right now, though, and his stuff is still elite in the right matchups. Let’s not forget that Senga boasted a 1.47 ERA over his first 13 starts last year before the injury. 

Today’s matchup is a favorable one for Senga at home. The Athletics have just a .296 wOBA (25th in MLB) and 88 wRC+ (23rd) this year. The offense also has a league-worst 29.4% strikeout rate against right-handed pitching thus far. Senga can quiet the lineup, especially considering his career 2.80 ERA at home. 

Meanwhile, the Mets should plate some runs against A’s starter Jacob Lopez. The lefty has a 6.48 ERA and 2.28 WHIP over his first two outings. It’s a small sample size, but Lopez also had a subpar 4.08 ERA last year. He struggled to a 5.40 ERA and 5.00 FIP on the road as well. 

New York’s offense has been terrible recently. However, the Mets have hit left-handed pitching fairly well. In the split, they have a .328 wOBA (ninth in MLB) and 109 wRC+ (10th). The lineup has a get-right matchup here after recently being held down by the Diamondbacks. Let’s back New York to win and lead after five innings. 

 

 

 

Best MLB Player Prop Bets & Other Picks Today, 4/11