Welcome back to another round of MLB Best Bets Today as the 2025 baseball season rolls on. 

Saturday’s baseball slate is another loaded one with 15 games on the MLB schedule. We have games going on all day and night with every team in action. As always, there are plenty of ways to go for our top MLB picks and predictions. Let’s focus on two games for our MLB best bets today before dishing out a few baseball player props and other picks to consider. 

Keep in mind, some of these odds or lines could move before first pitch. All bets below are for one unit unless otherwise noted. Without further ado, let’s dive into our MLB Best Bets Today.

 

 

 

MLB Picks, Predictions & Best Bets Today, 6/21

Our MLB Best Bets Today feature a pair of divisional matchups. First, the Houston Astros will look to get a road victory against the Los Angeles Angels. Then, the Philadelphia Phillies host the New York Mets after the NL East rivals battled it out on Friday night. Plus, don’t miss some top MLB player prop bets below. Check out these MLB predictions to make as you enjoy Saturday’s baseball action. 

 

 

 

Houston Astros vs. Los Angeles Angels Predictions: Saturday, June 21st

Let’s lead off our MLB best bets today with an AL West matchup. The Los Angeles Angels host the Houston Astros on Saturday night after the latter won yesterday’s series opener in extra innings. There’s value on the road squad to win again based on offensive splits and the starting pitchers. 

Brandon Walter has been impressive in the Houston rotation so far. He owns a 1.53 ERA and 0.91 WHIP through his first three starts. The left-hander was also lights-out in the minors this year before being called up, posting a 2.08 ERA in 11 appearances at Triple-A. 

Maybe Walter’s hot start is unsustainable, but he gets a favorable matchup tonight. The Angels have struggled against left-handed pitching all season with a .270 wOBA (28th in MLB), .212 batting average (28th), 28.1% K rate (30th), and 3.5% walk rate (30th). The offense also has subpar numbers vs. lefties over the past two weeks (.268 wOBA, 26.9% K rate, 2.8% walk rate).

Even on the road, Walter can stifle this Angels lineup. He boasts a 27.5% strikeout rate with a minimal 1.4% walk rate thus far. In the minors this year, he had a 27.5% K rate and a 3.9% walk rate. If he can continue to get swings-and-misses while limiting free passes, another solid outing is coming. 

On the other side, Jose Soriano starts for Los Angeles. He’s been up and down this season with a 3.54 ERA and 1.46 WHIP. Notably, Soriano has been notably worse at home with a 4.88 ERA and .346 wOBA allowed compared to a 2.78 ERA and .288 wOBA on the road. 

Yes, Soriano has been productive lately with a quality start in five of his last seven outings. Still, he profiles as an average or below-average starter. The Angels’ right-hander has a 19.0% K rate (28th percentile) and 10.8% walk rate (19th) with a lofty 46.5% hard-hit rate (14th). 

Meanwhile, the Astros are hitting well against right-handed pitching lately. Over the past week vs. righties, they have a .371 wOBA (5th in MLB), 143 wRC+ (3rd), and .308 BA (2nd). The Houston offense has also woken up lately, scoring 10+ runs four separate times in the past eight games. 

Let’s back the Astros to get the road win here. Houston is rolling lately with an 11-3 record in the last 14 games, winning by 2+ runs in seven of those 11 victories. 

 

 

 

New York Mets at Philadelphia Phillies Predictions: Saturday, June 21st

First place in the NL East is up for grabs between the New York Mets and Philadelphia Phillies this weekend. The division rivals started up their series last night as the Phillies took the opener, 10-2. Let’s see how to bet on Saturday’s showdown. 

Phillies starter Mick Abel has an impressive 2.21 ERA through his first four big-league starts. However, the rookie is likely due for negative regression moving forward. Abel’s 4.05 FIP and 4.75 xERA are notably higher as he’s benefited from a low .250 BABIP and an unsustainable 95.5% left-on-base rate. 

Plus, two of Abel’s starts so far have come against the lowly Pirates and Marlins offenses. He’s a talented prospect, but we can fade him in the right spots. Today profiles as that with the Mets in town. 

New York has a top-tier offense against right-handed pitching this season with a .331 wOBA (6th in MLB) and 115 wRC+ (3rd). Over the past two weeks vs. righties, the Mets boast a .360 wOBA (2nd) and 135 wRC+ (1st) in the split. The lineup should also wake up after being quieted by Zack Wheeler last night. 

Mets starter Griffin Canning started the season strong, but he’s come back down to Earth lately. He has a 6.75 ERA over his past five starts with a poor 17:16 K:BB ratio during this stretch. The struggles have hit the right-hander hard. He’s given up 10 runs over his last two starts combined. 

Now, Canning has to face a dangerous lineup on the road. The Phillies are a top-10 offense against right-handed pitching over the past week with a .349 wOBA, 128 wRC+, .799 OPS, and 10.3% walk rate. It doesn’t help that Canning has a 4.30 FIP on the road this year. 

The New York righty has some worrisome advanced metrics as well. His 47.2% hard-hit rate (11th percentile) and 10.9% walk rate (17th) are both career-worst marks. Plus, his 4.45 xERA is still a bit higher than his current 3.80 ERA. Another rough outing could be coming against Philadelphia here. 

Let’s take the over for the full game and first five innings. There were 12 total runs scored between these teams last night, and Saturday should see another high-scoring contest. An added factor is that both bullpens have been untrustworthy lately. 

 

 

 

Best MLB Player Prop Bets & Other Picks Today, 6/21

 

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