As we head into Week 1 of the 2021 season, running back continues to be one of the toughest positions to manage in fantasy football. It’s a volatile position with players constantly getting injured, benched, or cut on a regular basis. Even as this article is being written the Saints cut backup RB Latavius Murray, and the Ravens signed Le’Veon Bell to their practice squad. By the time you read this Murray may have already found a new team to play for.

Another thing that makes the RB position difficult to manage is that bell cow running backs have become increasingly hard. Fewer teams primarily use one RB. Instead, several teams have moved to a running back by committee (RBBC) approach that takes advantage of an individual players strengths and matches them to specific game situations. However, if you’ve made a sizeable draft day investment in a bell cow back, rostering or at least familiarizing yourself with his handcuff can sometimes be very rewarding. If you’re looking for proof, just ask the fantasy football managers who rostered both Panthers RB’s (Christian McCaffrey and Mike Davis) last season. 

Some backup RB’s not only have a direct path to a starting job but are also capable of contributing their own standalone fantasy production. Browns RB Kareem Hunt is one such example. He’s Nick Chubb’s handcuff, but last season he averaged 13.7 points per game in PPR formats. Cowboys RB Tony Pollard, who is Ezekiel Elliott’s handcuff, averaged a more modest 7.5 FPPG in the same format, but he scored at least 10.2 points in four games last season, including a huge 31.2-point performance in Week 15 against the 49ers.

Other handcuffs who either have standalone fantasy value or are widely regarded as potential high-quality handcuffs are Vikings RB Alexander Mattison, Seahawks RB Rashaad Penny, and Giants RB Devontae Booker.

With the violent, high contact nature of the position, RB’s all too often break down and suffer injuries. That inadvertently provides opportunities for under the radar backup RB’s with an eventual direct path to a starting job. 

For instance, with the Saints cutting Murray, RB Tony Jones Jr. becomes Alvin Kamara’s backup. Kylin Hill isn’t about to leapfrog Packers RB’s Aaron Jones or A.J. Dillon, but he’s a dynamic pass catching back with good speed who can carve out a role for himself. Damien Williams is considered a solid handcuff to Bears RB David Montgomery, but Khalil Herbert has a career 6.1 college career YPC average and has impressed head coach Matt Nagy this preseason. The Bengals are intrigued with rookie Chris Evans ability to catch passes, (something he wasn’t asked to do much in college). Perhaps he’ll help replace some of the 40+ catches that Giovani Bernard took with him to Tampa Bay.

Lastly, keep in mind that 2021 will be the NFL’s first 17-game regular season. It’s going to be a long season so don’t expect your fantasy RB to play all 17 games. If he does consider yourself lucky, but if there’s any season in which you’ll need to have an in-depth knowledge of as many fantasy RB’s as possible, it’s this one. 

When it comes to some teams, anticipating how they’ll use their backfield is easy. We know that Dalvin Cook is going to get most of the carries for the Vikings and if he gets hurt, Alexander Mattison will take over. 

On the other hand, there are some teams (Patriots, Broncos, Bucs…) whose depth charts and future RB usage aren’t as obvious. When it comes to those teams, we’re all going to need to watch Week 1’s games and read Week 1’s box scores in order to figure out how to manage our fantasy lineups for the upcoming weeks. 

We’ve researched preseason stats, individual player skill sets, coaching tendencies and more in order to create a handcuff grid which reflects our vision of what each NFL team’s backfield will look like and how they’ll be utilized in Week 1.

We still have questions with regard to how some teams will manage their backfields to start the season and hope that most of them will be answered by the time Monday Night Football is over. Use the RB Handcuff Grid that accompanies this article, and even more importantly, trust your own research and follow your own instincts when setting up your lineups this week. Let’s all win our Week 1 matchups and at the same time, get a better understanding of how to manage our own fantasy backfields based on Week 1’s results.

TeamPrimary RBChange of Pace3rd Down BackHandcuffIR/PUP/Susp.Note
Arizona CardinalsJames ConnerJonathan Ward/Enos BenjaminChase EdmondsChase Edmonds  
Atlanta FalconsMike DavisCordarrelle Patterson/Wayne GallmanCordarrelle PattersonWayne Gallman  
Baltimore RavensTy'Son WilliamsLatavius Murray/Trenton CannonLatavius MurrayLatavius MurrayJ.K. Dobbins/Gus Edwards/Justice HillDevonta Freeman and Le'Veon Bell are on the Ravens practice squad. Of the two Freeman is closest to being game ready. The Ravens also signed Trenton Cannon this week. He may get an occasional carry and is considered more of a special teams contributor.
Buffalo BillsZack MossMatt BreidaDevin SingletaryDevin Singletary RB Taiwan Jones will contribute to the Bills' special teams unit.
Carolina PanthersChristian McCaffreyChuba HubbardRoyce FreemanChuba Hubbard  
Chicago BearsDavid MontgomeryKhalil HerbertDamien WilliamsDamien WilliamsTarik Cohen 
Cincinnati BengalsJoe MixonSamaje PerineChris EvansSamaje Perine  
Cleveland BrownsNick ChubbD'Ernest Johnson/Demetric FeltonKareem HuntKareem Hunt Demetric Felton versatility gives him an opportunity to contribute to the Browns' run and passing game as well as to their special teams unit.
Dallas CowboysEzekiel ElliottTony PollardCorey ClementTony PollardRico DowdleCorey Clement should also contribute to the Cowboys' special teams unit.
Denver BroncosMelvin GordonJavonte Williams/Nate McCrary Javonte WilliamsMike Boone 
Detroit LionsJamaal WilliamsJermar JeffersonD'Andre SwiftD'Andre Swift  
Green Bay PackersAaron JonesA.J. DillonKylin HillA.J. Dillon  
Houston TexansPhillip LindsayMark Ingram/Rex BurkheadDavid JohnsonDavid Johnson  
Indianapolis ColtsJonathan TaylorMarlon Mack/Jordan WilkinsNyheim HinesMarlon Mack  
Jacksonville JaguarsJames RobinsonCarlos HydeDare OgunbowaleCarlos HydeTravis Etienne Jr. 
Kansas City ChiefsClyde Edwards-HelaireDarrel WilliamsJerick McKinnonDarrel Williams  
Las Vegas RaidersJosh JacobsPeyton BarberKenyan DrakeKenyan DrakeJalen Richard 
Los Angeles ChargersAustin EkelerJustin Jackson/Larry Rountree IIIJoshua KelleyJustin Jackson  
Los Angeles RamsDarrell Henderson Jr.Sony Michel/Jake FunkSony MichelSony MichelCam Akers 
Miami DolphinsMyles GaskinSalvon AhmedMalcolm BrownMalcolm Brown/Salvon Ahmed  
Minnesota VikingsDalvin CookAlexander Mattison Alexander MattisonKene Nwangu 
New England PatriotsDamien HarrisRhamondre Stevenson/J.J. TaylorJames WhiteRhamondre Stevenson  
New Orleans SaintsAlvin KamaraTony Jones Jr./Dwayne Washington Tony Jones Jr./Dwayne Washington Dwayne Washington may also contribute to the Saints' special teams unit as well.
New York GiantsSaquon BarkleyDevontae Booker/Elijhaa Penny/Gary Brightwell Devontae Booker  
New York JetsTevin ColemanTy Johnson/Michael CarterLa'Mical PerineTy Johnson  
Philadelphia EaglesMiles SandersKenneth GainwellBoston ScottKenneth Gainwell  
Pittsburgh SteelersNajee HarrisBenny Snell Jr.Kalen BallageBenny Snell Jr.Anthony McFarland 
San Francisco 49ersRaheem MostertTrey Sermon/Elijah MitchellJaMycal HastyTrey SermonJeff Wilson Jr. 
Seattle SeahawksChris CarsonRashaad Penny/Alex Collins/Travis HomerDeeJay DallasRashaad Penny  
Tampa Bay BuccaneersLeonard FournetteRonald Jones II/Ke'Shawn VaughnGiovani BernardRonald Jones II  
Tennessee TitansDerrick HenryJeremy McNichols/Mekhi SargentJeremy McNicholsJeremy McNicholsDarrynton Evans 
Washington TeamAntonio GibsonJaret PattersonJ.D. McKissicJ.D. McKissic