The holiday College Football Week 13 continues and now it's time to dive into top CFB DFS picks for Saturday's main slate on DraftKings and FanDuel. This Saturday's CFB Week 13 main slate features plenty of top teams and matchups to build college football DFS lineups around. We have a big rivalry and the slates highest game total as Washington and Washington State face off for the Apple Cup plus other high scoring games like Texas A&M travelling to LSU and Houston facing off against Central Florida. We also have other top teams in action like Alabama, Tennessee, Oklahoma State, Utah, SMU and Arizona.  In this CFB DFS Playbook, we'll break down top college football DFS picks for Saturday's main slate on DraftKings and FanDuel for the early/afternoon games. Check out my playbook for the 7pm night slate breakdown. The FanDuel main slate includes some night games but check out these top picks when building CFB DFS lineups on both sites. All the CFB Week 13 odds listed below are via DraftKings Sportsbook at the time of this writing. Let's now get into the top CFB DFS picks for Saturday's college football Week 13 slate on November 25th.


College Football Week 13 Schedule

CFB DFS Saturday Main Slate DraftKings

12p ET Pittsburgh @ Duke (-6.0) 42.0 O/U

12p ET Kentucky @ Louisville (-8.0) 49.5 O/U

12p ET Ohio State @ Michigan (-3.5) 47.0 O/U

12p ET Houston @ Central Florida (-13.5) 60.5 O/U

12p ET Texas A&M @ LSU (-12.0) 66.0 O/U

12p ET Navy @ SMU (-19.5) 45.5 O/U

3p ET Colorado @ Utah (-20.5) 48.0 O/U

3:30p ET BYU @ Oklahoma State (-16.5) 56.0 O/U

3:30p ET Arizona (-10.5) @ Arizona State 49.5 O/U

3:30p ET Alabama (-13.5) @ Auburn 47.5 O/U

3:30p ET Vanderbilt @ Tennessee (-27.0) 57.5 O/U

4p ET Washington State @ Washington (-16.5) 66.0 O/U


College Football Week 13 CFB DFS Picks

Top CFB DFS Quarterbacks

Jayden Daniels- LSU vs. Texas A&M ($11.0K DK/13.0K FD)

Jayden Daniels’ Heisman Trophy candidacy could come down to Saturday afternoon and his final regular season start against Texas A&M and their eighth ranked defense in the nation. He is ultra expensive but could use another huge game to impress voters so put your seat belts on as we could see another video game number output. Daniels accounted for eight touchdowns and 509 total yards against Georgia State last week after passing for more than 350 yards and rushing for another 200 plus against Florida the week before. He now leads the nation in total offense with 417.4 yards per game and is just the second player in SEC history to throw for 3,500 yards and rush for 1,000 yards in a season (Texas A&M’s Johnny Manziel did it first in 2012. Jayden Daniels is by far the highest projected scoring player on Saturday’s main slate.

John Rhys Plumlee- Central Florida vs. Houston ($8.2K DK/10.2K FD)

John Rhys Plumlee is finally getting healthy after missing three weeks with a knee injury earlier in the season. This week may be the strongest he’s been since last year as he comes off a game against Texas tech where he ran for 84 yards and threw for 248 yards and a touchdown. JRP is averaging 24.8 DK points over his last five games plus is carrying the ball an average of 12 times per game for a 64.0 yard per game average on the ground. He gets a tasty matchup against a bad Houston defense that allows 255.5 yards in the air and 163.6 yards on the ground and is one of the top values at his position on both DraftKings and FanDuel.

Joe Milton III- Tennessee vs. Vanderbilt ($7.5K DK)

Joe Milton has had an up and down season for the Volunteers. He has played well in some games and looked terrible in others but it’s not all his fault. There have been problems in the running backs room, and he also has lacked some chemistry with his receivers. His arm and natural talent are undisputed as we saw in the Georgia and Texas A& M games and now gets what should be a cake matchup at home against a terrible Vanderbilt defense. Tennessee has the highest implied point total of the slate (42.25) due to Vanderbilt allowing 264.2 passing yards and 176 rushing yards per game and Joe Milton III should be involved in most of those scores.

Other Top Quarterbacks:

Michael Penix, Washington ($10.4K DK/11.5K FD)- Penix Jr. is responsible for 33 touchdowns and 3,695 passing yards. He has thrown four or more touchdowns five times this season and thrown for over 300 yards in eight contests including three 400+ yard performances. 

Jalen Milroe, Alabama ($9.5K DK/11.2K FD)- Milroe comes into the Iron Bowl game completing 66.4% of his passes for 2,267 yards and 19 touchdowns with six interceptions. Only Jayden Daniels is averaging more yards per attempt than Milroe’s 10.6 this season.

Bryson Barnes, Utah ($7.1K DK)- Barnes has over 20 DK points in four of his last five games and has thrown eight touchdowns over his last three.

Jaylen Henderson, Texas A&M ($6.4K DK/8.4K FD)- In the last two weeks, Henderson has thrown for 410 yards and four touchdowns, coupled with 94 rushing yards and two scores on the ground. He should be playing catch up against a mediocre LSU defense all day. 

Jake Retzlaff, BYU ($5.9K DK/7.8K FD) The GPP low priced dart as Retzlaff had a fairly productive day against Oklahoma last week going 15-for-26 for 173 yards and two touchdowns. 


Top CFB DFS Running Backs

Ollie Gordon- Oklahoma State vs. BYU ($9.0K DK/11.5K FD)

Olie Gordon is in the midst of a monster season as the four time Big 12 Offensive Player of the Week leads the FBS in nearly every major rushing category, including rushing yards (1,414), rushing yards per game (128.5), 200-yard rushing games (2) and carries of at least 20 yards (18), 30 yards (14), 40 yards (7) and 70 yards (2). He is now the only FBS player in the past 10 years with 250 scrimmage yards in three straight games (Kansas, West Virginia and Cincinnati). His games against WVU and Cincinnati marked the most rushing yards for an OSU player in a two-game span (553) since Heisman-winner Barry Sanders posted 625 yards against Iowa and Texas Tech in 1988. Now he gets to face a BYU run defense that is allowing 177 yards on the ground. Do I need to say anymore? He won’t come cheap, but Ollie Brown is the top overall RB/WR on this main slate.

RJ Harvey- Central Florida vs. Houston ($7.2K DK/10.2K FD)

RJ Harvey is the Big 12's third-leading rusher with 1,160 yards and has become the first UCF back to surpass 1,000 rushing yards since Greg McCrae in 2018. He only had 78 yards in last week’s loss to Texas Tech, snapping a five-game streak with at least 100 yards. Eight of his 14 rushing touchdowns have come in the last three games. Starting with Darren McFadden back in 2006 and Ben Tate in 2009, UCF head coach Gus Malzahn has molded stud running back after stud running back and now Harvey joins the elite group. He ranks among the top 10 in the Big 12 Conference in every rushing category as he’s second in rushing touchdowns (14), third in yards per rush (6.11) and rushing yards (1,160), fourth in rushing yards per game (105.45) and fifth in rushing attempts (190). With Houston sputtering to the finish line expect UCF to put a bug number on the board today and Harvey should certainly get a piece of the pie.

Jaylen Wright- Tennessee vs. Vanderbilt ($5.2K DK)

Jaylen Wright is closing in on the 1,000-yard rushing mark as the Vols head into their season finale against Vanderbilt. Should he eclipse the mark, he’d be the first Tennessee running back to do so since Jalen Hurd ack in 2018.  Wright has had only one game this season where the opposing defense really shut him down and that was Missouri in Week 11 but other than that he’s been very good. He has six games with at least 100 yards rushing and last week ran for 90 yards on nine carries plus ran one in for a score. Wright has 938 yards, needing only 62 more to hit the 1,000-yard mark and Josh Heupel has been talking all week how important it is for this back to hit the big milestone. Jaylin Wright will find his way into many of my cash and GPP lineups today. 

LJ Johnson- SMU vs. NAVY ($4.8K DK)

LJ Johnson is a tough, downhill runner that plays mean and runs violently. He is everything SMU thought he would be coming from Texas A&M as he excels between the tackles and has the speed to get on the edge. It appears that Johnson has taken over as the RB1 for the Mustangs as he has over 20 carries and 100 yards in each of the last two games with a 106 yard/one touchdown game against North Texas and 115 yard/one touchdown game at Memphis. At $4.8K LJ Johnson is far too cheap for the workload he has been getting.

Rodney Hammond Jr.- Pittsburgh @ Duke ($4.5K DK)

If you follow my weekly Fantasy Alarm Playbook for the Saturday 7pm games, you know that I think Rodney Hammond Jr is a talented runner that has all the potential in the world. For most of the season Pitt’s running attack has been lacking as they have the lowest mark in the ACC in carries, rush yards and rushing touchdowns, averaging just 3.7 yards per attempt on the ground. This really hasn’t been the complete fault of the Panther runners because rushing success will be non-existent if there is no blocking upfront. Hammond Jr is a difference maker though and if gets action he will succeed. Even last week against Boston College, in a career best performance, Hammond didn’t receive a single carry until the second quarter. He had just 20 yards at the halftime break but finished with a career-high 145 yards, which included the game-winning 66-yard touchdown in the fourth quarter. He was dominating in his 15 carries, and this was the Hammond Jr we have been waiting to see all season.  Pittsburgh is a much better football team when they are running the ball effectively and now, they face a Duke run defense is mediocre at best. They are allowing 157 yards per game on the ground and 17.0 DK points to opposing RB1s. Hammond Jr is the wild card play of the day. 

Other Top Running Backs:

Blake Corum, Michigan ($8.4K DK/8.8K FD)- Corum, 888 rushing yards, is the nation's top scorer (120 points) with an NCAA-best 20 rushing touchdowns. He is always a top GPP play due to low ownership since his price tag is normally $8K plus. 

TreVeyon Henderson, Ohio State ($7.3K DK/8.4K FD)- Henderson has been straight fire since his return from injury, waking up the Buckeyes’ ground game and serving as a pass-catching asset out of the backfield. Over four games, he’s totaled 664 yards from scrimmage. 

Dillon Johnson, Washington ($7.0K DK/9.2K FD)- Johnson is the Husky’s leading rusher with 879 yards and 11 touchdowns on 152 carries. He is dealing with a foot injury- so pay attention to Discord on Saturday for up-to-date news.

Jonah Coleman, Arizona ($5.3K DK/7.7K FD)- Over the last 6 games, Coleman has 614 rushing yards and is averaging an eye popping 7.14 yards per carry. He gets a much easier matchup this week against Arizona State than he has been used to over the last few games. 

Aidan Robbins, BYU ($4.1K DK/5.7K FD)- Robbins carried the ball 22 times last week, running for 182 yards versus Oklahoma. He now has 16-plus carries in three of BYU’s last four games and is averaging 83.3 rushing yards over the same time span.

Tybo Rogers, Washington ($3.1K DK/5.0K DK)- This is a news related play as Dillon Johnson is questionable. If Johnson sits it would be no surprise if the Huskies turned the ball over to Rogers as the coaching staff has used him in nine games as he is considered UW’s fastest and shiftiest back. 


Top CFB DFS Wide Receivers

Malik Nabers & Brian Thomas Jr.- LSU vs. Texas A&M ($9.6K & $8.0K DK/10.8K FD & $9.7K FD)

LSU is the only team in the nation with two players named to the list of Biletnikoff semifinalists. Malik Nabers and Brian Thomas Jr. are the top combination of wide receivers in the nation as they have combined for 135 receptions for 2,445 yards and 26 touchdowns. It’s only the third time in school history LSU has had a pair of 1,000-yard receivers in the same season as they join Jarvis Landy and Odell Beckham Jr. in 2013 and Ja’Marr Chase and Justin Jefferson in 2019 in accomplishing the feat.

Nabers leads the nation in receiving yards with 1,424 and his 12 touchdowns rank fourth nationally. His 80 receptions lead the SEC and ranks No. 5 nationally and he has eight games with at least 100 receiving yards. Thomas has caught a TD pass in eight games and leads the nation with 14 touchdowns. He has 55 receptions for 1,021 yards so far this season. The have both topped the 100-yard mark in two straight games heading into the Texas A&M regular season-finale and we could very see it happen again. These are GPP-type salaries but if making multiple lineups I would make sure to get a few in with each receiver and their quarterback Jayden Daniels.

Tetairoa McMillan- Arizona vs. Arizona State ($7.0K DK/9.0K FD)

Tetairoa McMillan has quietly become one of the best receivers in the nation. The sophomore wide receiver has 69 catches for 976 yards and nine touchdowns this season and is now third in the Pac-12 in receiving yards behind only Oregon’s Troy Franklin and Washington’s Rome Odunze. McMillan, who is the highest-rated recruit to sign with Arizona during the modern recruiting era, broke out last season with 702 receiving yards and eight touchdowns on only 39 receptions. He has added another level to his game and now gets to face a soft Arizona State defense that is allowing opposing WR1’s to average 22.2 DK points against them. This is the highest price point of the season for McMillan, but it is still entirely too cheap for this matchup.

Brennan Presley- Oklahoma State vs. BYU ($5.9K DK/8.7K FD)

Brennan Presley caught 15 passes last week— the second-most in a game in program history — for a career-high 189 receiving yards in Oklahoma State’s 43-30 win against Houston. His performance earned him a 91.5 PFF grade on the week, the highest among any receiver in the country with at least five passing snaps played. Presley now has 18+ DK points in every game but one since Week 7 and is averaging 21.2 DK points over his last four contests. Now the slot receiver will be facing a BYU defense that is just ordinary and allows WR1’s to score an average of 18 DK points on four receptions and 71 yards. Head coach Mike Gundy should continue to target Presley heavy this week.

Squirrel White- Tennessee vs. Vanderbilt ($5.7K DK)

Dont’e Thornton is done for the season and that gives Squirrel White free reign in the slot on the Volunteer offense. White has scored double digit fantasy points in every game but one since Week 8 when he torched Alabama for a 10-111-1 line (30 DK points). He is averaging six targets a game over the last four and gets to see a bad Vanderbilt pass defense that is allowing 264.2 yards in the air and 5.2 receptions and 65.2 yards to WR1’s. With a 41.75 team total I expect Squirrel White will see plenty of action in the season finale. 

Other Top Wide Receivers:

Marvin Harrison Jr, Ohio State ($9.0K DK/9.5K FD)- Harrison Jr. has put the Buckeyes on his back in some huge spots this season like the 11-catch for 162 yard and touchdown game against Penn State earlier in the year. This season he has seven games where he has recorded 100 yards or more and has also scored in nine of 11 games with 14 total touchdowns.

Rome Odunze, Washington ($8.5K DK/10.4K FD)- Odunze has been Michael Penix’s top target this year as he has 66 catches for 1,206 yards and 11 touchdowns. Like Nabers and Harrison Jr., he is viable in all formats but doesn’t come cheap. 

Devaughn Vele, Utah ($5.0K DK)- Over the last three weeks Vele has scored 24.6, 22.5 and 29.1 DK points with Bryson Barnes at quarterback. He gets another solid matchup against Colorado.

Jordan Moore, Duke ($5.7K DK/8.0K FD)- Moore and Duke quarterback Grayson Loftis are becoming a top ACC combo as the receiver is averaging 11 targets, 7.5 receptions and 103 yards over the last two games. These are elite numbers.

Ramel Keyton, Tennessee ($4.3K DK)- Vanderbilt’s defense is bad and Keyton is cheap to slide in as a value play as he averages three targets and 42 yards over his last four games.

Dalton Carnes, Houston ($3.5K DK/5.7K FD)- The redshirt freshman is seeing more and more time on the field and last week caught three passes for 44 yards against Oklahoma State. 

Moose Muhammad III, Texas A&M ($4.0K DK/4.6K FD)- With Jimbo Fisher gone Muhammad III had four catches for 104 yards and one score against Abilene Christian last week. He’s worth a shot in GPPs as it appears new HC Elijah Robinson will utilize the uber-talented receiver much more.


John Rhys Plumlee, Central Florida

Ollie Gordon Oklahoma State

LJ Johnson (Value), SMU

FANDUEL CORE (Early Games)

John Rhys Plumlee, Central Florida

Ollie Gordon Oklahoma State

Tetairoa McMillan, Arizona