Running Backs

TeamRB1RB2RB3INJ/SUS
Arizona CardinalsKerwynn WilliamsElijhaa PennyD.J. FosterDavid Johnson
Atlanta FalconsDevonta FreemanTevin ColemanTerron Ward 
Baltimore RavensAlex CollinsDanny WoodheadJavorius Allen 
Buffalo BillsLeSean McCoyMike TolbertTravaris Cadet 
Carolina PanthersJonathan StewartChristian McCaffreyFozzy Whittaker 
Chicago BearsJordan HowardTarik CohenBenny Cunningham 
Cincinnati BengalsJoe MixonGiovani BernardBrian HillJeremy Hill
Cleveland BrownsIsaiah CrowellDuke JohnsonMatthew Dayes 
Dallas CowboysEzekiel ElliottRod SmithAlfred Morris 
Denver BroncosC.J. AndersonDevontae BookerJamaal Charles 
Detroit LionsAmeer AbdullahTheo RiddickZach Zenner 
Green Bay PackersJamaal WilliamsAaron Jones Ty Montgomery
Houston TexansLamar MillerAndre EllingtonAlfred BlueD'Onta Foreman
Indianapolis ColtsFrank GoreMarlon MackRobert Turbin 
Jacksonville JaguarsLeonard FournetteChris IvoryT.J. Yeldon 
Kansas City ChiefsKareem HuntCharcandrick WestAkeem HuntSpencer Ware
Los Angeles ChargersMelvin GordonBranden OliverAustin Ekeler 
Los Angeles RamsTodd GurleyMalcolm BrownJustin DavisLance Dunbar
Miami DolphinsKenyan DrakeSenorise PerryDe'Veon SmithDamien Williams
Minnesota VikingsLatavius MurrayJerick McKinnonMack BrownDalvin Cook
New England PatriotsDion LewisMike GillisleeJames WhiteRex Burkhead
New Orleans SaintsMark IngramAlvin KamaraTrey Edmunds 
New York GiantsOrleans DarkwaWayne GallmanShane Vereen 
New York JetsBilal PowellMatt ForteElijah McGuire 
Oakland RaidersMarshawn LynchDeAndre WashingtonJalen Richard 
Philadelphia EaglesJay AjayiLeGarrette BlountWendell SmallwoodDarren Sproles
Pittsburgh SteelersLe'Veon BellFitzgerald ToussaintStevan RidleyJames Conner
San Francisco 49ersCarlos HydeMatt BreidaRaheem Mostert 
Seattle SeahawksMike DavisEddie LacyJ.D. McKissicChris Carson
Tampa Bay BuccaneersPeyton BarberDoug MartinCharles Sims 
Tennessee TitansDeMarco MurrayDerrick HenryDavid Fluellen 
Washington RedskinsSamaje PerineByron MarshallLeShun DanielsRobert Kelley

Top Handcuffs

Mike Gillislee, NE- Gillislee has been inactive for the past few weeks with Rex Burkhead taking his spot however Burkhead suffered an injury in Week 15 that is expected to keep him out of the lineup for the next few weeks.  Gillislee does not offer the pass catching abiltiy that Burkhead possess but he should take over as the short yardage and goal line carries which is a role he had earlier this season when Burkhead was on the shelf.

Peyton Barber, TB- Doug Martin was scratched in Week 15 due to a team rules violation and though he could very well be active in Week 16 against the Saints we have seen Barber average 71 rushing yards per game over the last three weeks while chipping in with a handful of receptions as well.  Though the Saints defense has been much improved this season Barber still holds value.

Elijhaa Penny, ARI- The Cardinals placed Adrian Peterson on IR which lead to Kerwynn Williams as the lead back but he suffered an injury in Week 15 which has him questionable for the team's Week 16 matchup against the Giants.  After the Williams injury the Cardinals turned to Penny and he totaled 45 yards on 10 carries.  If he starts this week he will have a very favorable matchup and could be a decent flex play for those in need of a running back this week.

Wide Receivers

TeamWR1WR2WR3INJ/SUS
Arizona CardinalsLarry FitzgeraldJohn BrownJ.J. Nelson 
Atlanta FalconsJulio JonesMohamed SanuTaylor Gabriel 
Baltimore RavensMike WallaceJeremy MaclinBreshad Perriman 
Buffalo BillsKelvin BenjaminZay JonesAndre HolmesJordan Matthews
Carolina PanthersDevin FunchessRussell ShepardCurtis Samuel 
Chicago BearsKendall WrightDontrelle InmanJoshua BellamyCameron Meredith
Cincinnati BengalsA.J. GreenBrandon LaFellJohn Ross 
Cleveland BrownsJosh GordonCorey ColemanRicardo Louis 
Dallas CowboysDez BryantCole BeasleyTerrance Williams 
Denver BroncosDemaryius ThomasEmmanuel SandersBennie Fowler III 
Detroit LionsGolden TateMarvin JonesKenny Golladay 
Green Bay PackersDavante AdamsJordy NelsonRandall Cobb 
Houston TexansDeAndre HopkinsWill FullerBraxton MillerBruce Ellington
Indianapolis ColtsT.Y. HiltonDonte MoncriefChester Rogers 
Jacksonville JaguarsMarqise LeeDede WestbrookKeelan ColeAllen Robinson
Kansas City ChiefsTyreek HillChris ConleyAlbert Wilson 
Los Angeles ChargersKeenan AllenTyrell WilliamsTravis Benjamin 
Los Angeles RamsRobert WoodsSammy WatkinsCooper Kupp 
Miami DolphinsJarvis LandryDeVante ParkerKenny Stills 
Minnesota VikingsAdam Thielen Stefon DiggsMichael Floyd 
New England PatriotsBrandin CooksChris HoganDanny AmendolaJulian Edelman
New Orleans SaintsMichael ThomasTed GinnWillie Snead 
New York GiantsSterling ShepardRoger LewisTavarres KingOdell Beckham 
New York JetsRobby AndersonJermaine KearseChad HansenQuincy Enunwa
Oakland RaidersMichael CrabtreeSeth RobertsCordarrelle Patterson 
Philadelphia EaglesAlshon JefferyNelson AgholorTorrey Smith 
Pittsburgh SteelersJuJu Smith-SchusterMartavis BryantEli RogersAntonio Brown
San Francisco 49ersMarquise GoodwinAldrick RobinsonLouis MurphyPierre Garcon
Seattle SeahawksDoug BaldwinPaul RichardsonTyler Lockett 
Tampa Bay BuccaneersMike EvansDeSean JacksonAdam Humphries 
Tennessee TitansRishard MatthewsEric DeckerCorey Davis 
Washington RedskinsJamison CrowderJosh DoctsonRyan Grant 

Top Handcuff

Martavis Bryant, PIT-  Antonio Brown suffered an injury that will cost him the rest of the regular season and with that injury Bryant along with JuJu Smith-Schuster and Eli Rogers will all see increased value given the additional targets in the Steelers passing attack.  Against New England Bryant caught four passes for 59 yards and a touchdown.  He will look to carry that big play ability into Week 16 against a bad Texans defense.

Keelan Cole, JAX-  Cole has scored touchdowns in three straight weeks and in Week 15 he put forth a career game, catching seven passes for 186 yards and a touchdown. With Marqise Lee expected to miss Week 16 due to an ankle injury Cole figures to be a top target of Blake Bortles in a favorable matchup against the 49ers.  Along with Cole fantasy owners should take interest in Jaydon Mickens who caught four passes for 61 yards and two touchdowns.
 

Tight Ends

TeamTE1TE2TE3INJ/SUS
Arizona CardinalsRicky Seals-JonesJermaine GreshamTroy Niklas 
Atlanta FalconsAustin HooperLevine ToiloloEric Saubert 
Baltimore RavensBenjamin WatsonNick BoyleMaxx Williams 
Buffalo BillsCharles ClayNick O'LearyLogan Thomas 
Carolina PanthersGreg OlsenEd DicksonChris Manhertz 
Chicago BearsDion SimsAdam ShaheenDaniel BrownZach Miller
Cincinnati BengalsTyler KroftC.J. Uzomah Tyler Eifert
Cleveland BrownsSeth DeValveDavid NjokuRandall Telfer 
Dallas CowboysJason WittenJames HannaGeoff Swaim 
Denver BroncosA.J. DerbyVirgil GreenJeff Heuerman 
Detroit LionsEric EbronDarren FellsMichael Roberts 
Green Bay PackersLance KendricksRichard Rodgers  
Houston TexansStephen AndersonRyan Griffin C.J. Fiedorowicz
Indianapolis ColtsJack DoyleDarrell DanielsBrandon Williams 
Jacksonville JaguarsMarcedes LewisBen KoyackJames O'Shaughnessy 
Kansas City ChiefsTravis KelceDemetrius HarrisRoss Travis 
Los Angeles ChargersAntonio GatesSean Culkin Hunter Henry
Los Angeles RamsTyler HigbeeGerald EverettDerek Carrier 
Miami DolphinsJulius ThomasAnthony FasanoMarQueis Gray 
Minnesota VikingsKyle RudolphDavid MorganBlake Bell 
New England PatriotsRob GronkowskiDwayne AllenJacob Hollister 
New Orleans SaintsJosh HillMichael Hoomanawanui Coby Fleener
New York GiantsEvan EngramRhett EllisonJerell Adams 
New York JetsAustin Seferian-JenkinsEric TomlinsonNeal Sterling 
Oakland RaidersJared CookLee SmithClive Walford 
Philadelphia EaglesZach ErtzBrent CelekTrey Burton 
Pittsburgh SteelersJesse JamesVance McDonaldXavier Grimble 
San Francisco 49ersGeorge KittleGarrett CelekLogan Paulsen 
Seattle SeahawksJimmy GrahamLuke WillsonNick Vannett 
Tampa Bay BuccaneersCameron BrateO.J. HowardAntony Auclair 
Tennessee TitansDelanie WalkerPhillip SupernawJonnu Smith 
Washington RedskinsVernon DavisNiles PaulJeremy SprinkleJordan Reed

Top Handcuffs

Antonio Gates, LAC- The 37-year old Gates is expected to see a large role in the Chargers offense in Week 16 after starting tight end Hunter Henry was placed on IR due to an injury suffered in Week 15.  Gates caught a touchdown pass in Week 15 to add to his already Hall of Fame resume.  Philip Rivers does like targeting his tight ends and though he is certainly a big risk we could very well see Gates look to end his career on a high note over the final two weeks of the regular season.