Welcome to the DFS Optimal Lineups for the NFL Week 16 Saturday slate!

Remember, in a two-game slate we stay away from cash games because the player overlap is too great and you get a ton of duplicate lineups which ends up raising the pay-lines and reducing the amount you win if you do cash. We stick to the GPP contests -- single-entry, more specifically -- and try to find ways to mix in the top plays with those low-owned, low-cost options who have strong match-ups and a chance to go off.

SIDE NOTE: The pricing may be off for some of the players on these lineups but I have entered all of these lineups on their respective sites and all salaries fit. The DFS sites have too many different slates for us to get all the pricing specific just to the Saturday slate.

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