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Every week presents a new set of challenges in daily fantasy football. Injuries, matchups and weather are just a few of the factors that we have to consider as we build our lineups. Luckily for you, I have spent the entire week consolidating this information down to what you see below. 

These are the optimal DFS NFL Lineups for the two major DFS sites and the two main contest formats. I strongly suggest starting out with 50/50's (double ups) until you are winning a high percentage of those contests. Then and only then it is time to move on to the larger tournaments (GPPs). 

Here are my Optimal DFS Lineups for Week 11:

DRAFT KINGS CASH GAMES (50/50's)

POSPlayerTeamPriceComments
QBDrew BreesSaints8,300Elite production for less than elite price at home
RB1Alfred BlueTexans3,000The key that unlocks all kinds of possibilities
RB2Jamaal CharlesChiefs7,100Charles could touch the ball 30+ times on Sunday
WR1Brandon Marshall Bears5,800Ridiculously low price for top 8 fantasy WR
WR2Jordan MatthewsEagles4,500Sanchez's main WR, priced before MNF breakout
WR3Pierre GarconRedskins4,000Garcon is RGIII's favorite target & will get 5+ rec
TEJimmy GrahamSaints7,000Graham is going to destory the soft Bengals D
FLEXAntonio BrownSteelers7,800The surest thing in fantasy football
DSTTennesseeTitans2,400Cheapest D but still quite respectable 

DRAFT KINGS TOURNAMENTS (GPP's)

POSPlayerTeamPriceComments
QBMark SanchezEagles5,800Remember he has 12 career rushing TD's
RB1Jamaal CharlesChiefs7,100Charles could touch the ball 30+ times on Sunday
RB2Alfred BlueTexans3,000The key that unlocks all kinds of possibilities
WR1A.J. GreenBengals6,000Looking for multi TD ability at value price
WR2Brandon Marshall Bears5,800Ridiculously low price for top 8 fantasy WR
WR3Kelvin BenjaminPanthers4,900Another multi TD WR for cheap
TEJimmy GrahamSaints7,000Graham is going to destory the soft Bengals D
FLEXAntonio BrownSteelers7,800The surest thing in fantasy football
DSTTennesseeTitans2,400Cheapest D but still quite respectable 

FANDUEL CASH GAMES (GPP'S)

POSPlayerTeamPriceComments
QBMark SanchezEagles6,900Price not reflective of MNF performance
RB1Jeremy HillBengals6,500Great price for TD heavy scoring format
RB2Alfred BlueTexans6,400Still a good price for high TD potential
WR1Calvin JohnsonLions9,000Cardinals allow 6th most points to WR's
WR2Brandon MarshallBears7,100Double digit targets very likely
WR3Kelvin BenjaminPanthers6,600Multi TD potential very time out
TEJimmy GrahamSaints7,900Bengals allow 4th most points to TE's
KNick NovakChargers4,500Never pay for a kicker
DSTHoustonTexans5,100J.J. Watt is always fantasy worthy

FANDUEL TOURNAMENTS (GPP'S)

POSPlayerTeamPriceComments
QBRobert Griffin IIIRedskins7,400Bucs defense is atrocious
RB1Frank Gore49ers7,000Giants give up 2nd most points to RB's
RB2Alfred BlueTexans6,400Just impossible to pass up this week
WR1Julio JonesFalcons8,200Panthers D given up 14 TD's to WR's
WR2A.J. GreenBengals8,300Saints give up 5th most points to WR's
WR3Brandon MarshallBears7,100Double digit targets very likely
TETravis KelceChiefs5,900If Fasano is out he'll be an every down TE
KNick NovakChargers4,500Never pay for a kicker
DSTHoustonTexans5,100J.J. Watt is always fantasy worthy