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It's easy to put together a DFS lineup. Just pick a bunch of your favorite players and sprinkle in some superstars that you hate and voila! But putting together winning DFS lineups on a consistent basis takes a lot of work. But that is what we do here at the DFS Playbook. We spend hours going over all potential players and selecting the absolute best of the best for our DFS NFL Playbook. Then, we run al of the possible combiations to come up with the absolute best of the best lineups for both cash games (50/50) & tournaments (GPP's) and do so for both Draft Kings and Fanduel.
Here are the optimal DFS lineups for NFL Week 10:
DRAFT KINGS CASH GAMES (50/50'S)
| POS | Player | Team | Price | Comments |
| QB | Ben Roethlisberger | Steelers | 7,500 | Going with hottest QB in NFL for cash games |
| RB1 | DeMarco Murray | Cowboys | 8,600 | Murray is going to rush for 200+ yards |
| RB2 | LeSean McCoy | Eagles | 5,600 | If Polk doesn't steal his TDs last week he's 2k more |
| WR1 | Antonio Brown | Steelers | 8,700 | The surest thing in fantasy football |
| WR2 | Brandon Marshall | Bears | 5,600 | Could grab multi TD's in high scoring game |
| WR3 | Kelvin Benjamin | Panthers | 4,200 | Too much value to pass up, will be highly owned |
| TE | Owen Daniels | Ravens | 3,300 | 12-111-1 in last two games |
| FLEX | James Jones | Raiders | 3,800 | Averages 12.9 PPG on Draft Kings |
| DST | San Francisco | 49ers | 2,700 | Still a strong defensive team |
DRAFT KINGS TOURNAMENTS (GPP'S)
| POS | Player | Team | Price | Comments |
| QB | Mark Sanchez | Eagles | 5,400 | Hard to pass up at this price |
| RB1 | DeMarco Murray | Cowboys | 8,600 | Murray is going to rush for 200+ yards |
| RB2 | Bobby Rainey | Buccnaeers | 4,400 | Especialy if Sims doesn't play Rainey is gold |
| WR1 | Antonio Brown | Steelers | 8,700 | The surest thing in fantasy football |
| WR2 | Brandon Marshall | Bears | 5,600 | Could grab multi TD's in high scoring game |
| WR3 | Kelvin Benjamin | Panthers | 4,200 | Too much value to pass up, will be highly owned |
| TE | Jimmy Graham | Saints | 6,300 | The best TE in the business |
| FLEX | Torrey Smith | Ravens | 3,500 | Has 11-195-4 in 3 of last 4 games |
| DST | Baltimore | Ravens | 3,200 | Experienced D at home Vs rookie QB |
FANDUEL CASH GAMES (50/50'S)
| POS | Player | Team | Price | Comments |
| QB | Ben Roethlisberger | Steelers | 8,300 | The hottest QB in the NFL right now |
| RB1 | DeMarco Murray | Cowboys | 9,300 | Murray is going to rush for 200+ yards |
| RB2 | LeSean McCoy | Eagles | 7,700 | Panthers give up 2nd most points to RB's |
| WR1 | Julio Jones | Falcons | 8,000 | Julio overdue for huge game against lowly Bucs |
| WR2 | Kelvin Benjamin | Panthers | 6,700 | Too much value to pass up, will be highly owned |
| WR3 | James Jones | Raiders | 5,400 | Jones averages 10 PPG on FD |
| TE | Larry Donnell | Giants | 5,300 | Way to attack Seahawks D is via the TE |
| K | Matt Bryant | Falcons | 4,500 | Never pay for a kicker |
| DST | St. Louis | Rams | 4,600 | Quinn/Donald starting to dominate of late |
FANDUEL TOURNAMENTS (GPP'S)
| POS | Player | Team | Price | Comments |
| QB | Mark Sanchez | Eagles | 6,600 | Hard to pass up at this price |
| RB1 | DeMarco Murray | Cowboys | 9,300 | Murray is going to rush for 200+ yards |
| RB2 | Frank Gore | 49ers | 6,800 | 49ers will run the ball a lot this week |
| WR1 | Julio Jones | Falcons | 8,000 | Julio overdue for huge game against lowly Bucs |
| WR2 | Brandon Marshall | Bears | 7,300 | Could grab multi TD's in high scoring game |
| WR3 | Kelvin Benjamin | Panthers | 6,700 | Too much value to pass up, will be highly owned |
| TE | Larry Donnell | Giants | 5,300 | Way to attack Seahawks D is via the TE |
| K | Matt Bryant | Falcons | 4,500 | Never pay for a kicker |
| DST | Baltimore | Ravens | Experienced D at home Vs rookie QB |