Arizona Cardinals at St. Louis Rams--8:20PM (THURS)
Sit--Steven Jackson, RB (STL)
Reason--The Cardinals have yet to give up a 100-yard rusher this season and have allowed just one touchdown on the ground. On the other hand Jackson has yet to rush for more than 100 yards rushing for a total of 195 yards in four games, so this doesn’t look to be a game you want to start him.
Baltimore Ravens at Kansas City Chiefs--1:00PM
Start--Dwayne Bowe, WR (KC)
Reason--This isn’t the best of matchups for Bowe and the rest of the Chiefs, but through the first four games Bowe is tied for the league-lead with 49 targets and is in the top 10 in fantasy points. The Ravens have allowed two touchdowns to opposing wide receivers and are giving up an average of just over 20 fantasy points, so expect a solid game from Bowe.
Miami Dolphins at Cincinnati Bengals--1:00PM
Start--Reggie Bush, RB (MIA)
Reason--Despite playing injured last week, Bush was still productive, even against a solid Cardinals rush defense. This week he is matched up against the Bengals who have allowed four rushing touchdowns through the first four weeks of the season and have also allowed three games of 99 yards or more allowed to opposing running backs.
Cleveland Browns at New York Giants--1:00PM
Sit--Ahmad Bradshaw, RB (NYG)
Reason--The Browns are one of the worst teams in the NFL, but they have yet to give up a rushing touchdown to opposing running backs and that includes holding Ray Rice and LeSean McCoy out of the end zone. The Giants are a pass first team and will likely attack the Browns vulnerable pass defense early and often in this contest, so Bradshaw isn’t much of a play this week.
Green Bay Packers at Indianapolis Colts--1:00PM
Sit--Greg Jennings, WR (GB)
Reason--Jennings was forced to leave the Packers Week 4 game against the Saints early in the first half and never returned. He re-aggravated his groin, which has forced him to miss time already this season and may be out once against in Week 5, so I suggest finding another option in case he is out once again.
Philadelphia Eagles at Pittsburgh Steelers--1:00PM
Sit--Rashard Mendenhall, RB (PIT)
Reason--The Steelers expect to have Mendenhall back in the backfield in Week 5, but this isn’t the best of matchups for his return. The Eagles have been great against the run this season and have allowed just one 100-yard rusher through the first four weeks, so look for a different option here.
Atlanta Falcons at Washington Redskins--1:00PM
Start--Tony Gonzalez, TE (ATL)
Reason--Week 4 was the first week that the Redskins didn’t allow a touchdown to an opposing tight end, but that was because the Buccaneers don’t use their tight ends too often in the passing game. Gonzalez has scored the most fantasy points through the first four weeks and is the fourth-most targeted tight end in the league, so this is looking like a great matchup for him this week.
Chicago Bears at Jacksonville Jaguars--4:05PM
Sit--Jay Cutler, QB (CHI)
Reason--Cutler is coming off of a solid game on Monday night, but will be matched up against a solid Jaguars secondary that can hold their own. The Bears will be able to beat them on the ground, so expect to see a lot of running from the Bears which will limit the production from Cutler and the passing game.
Seattle Seahawks at Carolina Panthers--4:05PM
Sit--DeAngelo Williams, RB (CAR)
Reason--The Seahawks have yet to allow a 100-yard rusher this season and the Panthers running backs have yet to have a big game. Expect this game to follow the trends set by the two teams, which will likely result in a dismal game for Williams and the rest of the Panthers backfield.
Tennessee Titans at Minnesota Vikings--4:25PM
Start--Vikings Defense/Special Teams (MIN)
Reason--The Vikings are 3-1 and a lot of that has to do with the play of their defense. They are causing a lot of turnovers and have stabilized themselves in both the running and passing game making them one of the better units this season. This week they are going up against a backup quarterback with a lot of question marks at the skill positions so this is a great week to start this unit.
Buffalo Bills at San Francisco 49ers--4:25PM
Start--Alex Smith, QB (SF)
Reason--The Bills secondary has allowed nine touchdowns to opposing quarterbacks so far this season and I expect the 49ers to take advantage of the vulnerable defense. This game could get ugly so his passing attempts may be low, but with his efficiency he should do enough early in the game to be a solid start this week.
Denver Broncos at New England Patriots--4:25PM
Start--Jacob Tamme, TE (DEN)
Reason--The Patriots defense has improved significantly from last season, but against opposing tight ends, that’s a different story. They are giving up the second-most fantasy points to opposing tight ends this season and have allowed three touchdowns over the last two weeks. Quarterback Peyton Manning likes to target Tamme so expect the Broncos to exploit this situation making him a solid play for this week.
San Diego Chargers at New Orleans Saints--8:20PM
Sit--Chargers Defense/Special Teams (SD)
Reason--The Saints may be 0-4, but they are still racking up the points through their first four games and have forced not allowed opposing defenses to score much against them in terms of fantasy. The Chargers unit is solid, but this game will likely be a shoot out, which makes them a bad play this week.
Houston Texans at New York Jets--8:30PM (MON)
Sit--Shonn Greene, RB (NYJ)
Reason--Greene has found his way onto this article a few weeks now and mostly as a player to sit. This week the Jets are matched up against a Texans defense that has not allowed a score on the ground this season and with the Jets blocking issues, this could be another bad game for Greene and the rest of the Jets offense.
Week 5 Bye Weeks--Dallas Cowboys, Detroit Lions, Oakland Raiders, Tampa Bay Buccaneers
Matthew Beck is a Fantasy Sports Columnist for Rotoinfo.com. If you have any questions or comments feel free to e-mail him at firstname.lastname@example.org. Also follow him on Twitter @MatthewRBeck for up-to-date Q&A and fantasy information.
Accomplished chef, journalist and dedicated fantasy sports player. When Matt's not in the kitchen, he's preparing the recipe for fantasy sports success. He is...The Fantasy Chef.
All form fields are required.